Metabotropic Glutamate Receptor 8-Expressing Nerve Terminals Target Subsets of GABAergic Neurons in the Hippocampus

Ferraguti, Francesco; Klausberger, Thomas; Cobden, Philip; Baude, Agnes; Roberts, J. David B.; Szucs, Peter; Kinoshita, Ayae; Shigemoto, Ryuichi; Somogyi, Peter; Dalezios, Yannis

doi:10.1523/jneurosci.2547-05.2005

Metabotropic Glutamate Receptor 8-Expressing Nerve Terminals Target Subsets of GABAergic Neurons in the Hippocampus

Presynaptic metabotropic glutamate receptors (mGluRs) show a highly selective expression and subcellular location in nerve terminals modulating neurotransmitter release. We have demonstrated that alternatively spliced variants of mGluR8, mGluR8a and mGluR8b, have an overlapping distribution in th…