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The multiple effects of amino acids on the early stages of calcium carbonate crystallization
Open accessAbstract
Proteins have found their way into many of Nature’s structures due to their structural stability, diversity in function and composition, and ability to be regulated as well as be regulators themselves. In this study, we investigate the constitutive amino acids that make up some of these proteins which are involved in CaCO 3 mineralization – either in nucleation, crystal growth, or inhibition processes. By assaying all 20 amino acids with vapor diffusion and in situ potentiometric titration, we have found specific amino acids having multiple effects on the early stages of CaCO 3 crystallization. These same amino acids have been independently implicated as constituents in liquid-like precursors that form mineralized tissues, processes believed to be key effects of biomineralization proteins in several biological model systems.
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“Aspartic acids in particular were shown to modify calcite crystal morphology by altering the surface energy at certain crystallographic facies.36,42−44”
From Organic Controls over Biomineral Ca-Mg Carbonate Compositions and Morphologies (2023) · cites this paper as [36]
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“Despite extensive works on the effects of amino acids on the calcium carbonate system,33−36 the effects of amino acids and chitins on Ca–Mg carbonate crystallization are poorly constrained.”
From Organic Controls over Biomineral Ca-Mg Carbonate Compositions and Morphologies (2023) · cites this paper as [36]
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Metadata
- Authors
- Picker, A., Kellermeier, M., Seto, J., Gebauer, D., & Cölfen, H.
- Affiliations
- University of Konstanz (DE)
- Venue
- Zeitschrift für Kristallographie - Crystalline Materials
- Publisher
- Walter de Gruyter GmbH
- Published
- 2012-10-15
- Volume
- 227
- Issue
- 11
- Pages
- 744-757
- ISSN
- 2194-4946 (ISSN-L)
- OpenAlex
- W2143726201
- Cited by
- 103
- References
- 67
- Citations by year
- 2026: 14 · 2025: 7 · 2024: 11 · 2023: 9 · 2022: 9 · 2021: 6 · 2020: 6 · 2019: 5 · 2018: 4 · 2017: 6 · 2016: 9 · 2015: 6 · 2014: 8 · 2013: 3
- FWCI
- 2.20
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Zeitschrift für Kristallographie - Crystalline Materials (publishedVersion)
- KOPS (University of Konstanz) (submittedVersion)
- eSpace (Curtin University) (submittedVersion)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Calcium Carbonate Crystallization and Inhibition
- Physical Sciences › Materials Science › Materials Chemistry › Crystallization and Solubility Studies
- Physical Sciences › Environmental Science › Environmental Engineering › Microbial Applications in Construction Materials
- Keywords
- amino acids, calcium carbonate crystallization
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