Disease-associated tau impairs mitophagy by inhibiting Parkin translocation to mitochondria

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Items 201–267 of 267

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8. Molecular linkages among Aβ, tau, impaired mitophagy, and mitochondrial dysfunction in Alzheimer’s disease
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12. The absence of Parkin in hTau mice leads to synaptic mitochondrial dysfunction, alterations to the synaptic proteome, and increased phosphorylated tau in the Hippocampus
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15. Tau-induced mitochondrial reverse electron transport drives neurodegeneration
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16. Glucose, glycolysis, and neurodegenerative disorders
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17. Re-energising the brain: glucose metabolism, Tau protein and memory in ageing and dementia
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18. MEC-12/alpha tubulin regulates mitochondrial distribution and mitophagy during oxidative stress in C. elegans
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19. PINK1 Deficiency Aggravates the β-amyloid-attenuated Mitophagy-lysosomal Degradation in PC12 Cells
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20. Research Progress of Mitophagy in Alzheimer's Disease
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21. Accumulation of Tau in Extracellular Vesicles Disturbs the Astrocytic Mitochondrial System
    Romain Perbet, Valentin Zufferey, Élodie Leroux, E. Parietti, Jeanne Espourteille, Lucas Culebras, Sylvain Perriot, R. du Pasquier, S. Bégard, V. Deramecourt et al. · 2023 · bioRxiv
22. The Juvenile Parkinson's Disease Mutation C212Y Impairs Mitochondrial Homeostasis in a Caenorhabditis elegans Model
    Eyal Spector, Lirin Michaeli, Anat Nitzan, Hanna Grobe, Gabriel Axel, Ulrike Bening Abu‐Shach, Hen Zinger, Cátia A. Carvalho, Ronen Zaidel‐Bar, Limor Broday · 2025 · The FASEB Journal
23. Genetic factors and comorbid pathologies interact to drive regional mitophagy alterations in Lewy body dementia
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25. Targeting tau-mitochondrial crosstalk in Alzheimer’s disease with an Integrative multi-omics and artificial intelligence driven tools for the development of disease-modifying therapeutics
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26. Mitophagy in cisplatin-induced kidney injury: regulatory mechanisms and therapeutic targets
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27. Tau protein as a regulator of mitochondrial function and dynamics
    Eleni N. Tsakiri, Carlos Campos‐Marques, Christina Ploumi, Kalliopi Skourti, Antonis Roussos, Eirini Mytilinaiou, Anastasia Vamvaka-Iakovou, Ildete L. Ferreira, Chrysoula Dioli, Despoina D. Gianniou et al. · 2026 · Proceedings of the National Academy of Sciences
28. Mitophagy Impairments as Culprit of Alzheimer’s Disease
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29. Assessing mitochondrial number and morphology in a C. elegans model of human tauopathy
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30. Targeted degradation of aberrant Tau for the discovery of Pulsatilla chinensis in Alzheimer’s disease
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31. Astrocytic IGF-1 and IGF-1R Orchestrate Mitophagy in Traumatic Brain Injury
    Ren Dabin, Wei Chen, Shu Liang, Cao Ke, Zhihan Wang, Ping Zheng · 2020
32. Selective Disruption of Drp1-Independent Mitophagy and Mitolysosome Trafficking by an Alzheimer’s Disease Relevant Tau Modification in a Novel C. elegans Model
    Sanjib K Guha, Anson Cheng, Trae Carroll, Dennisha P. King, Shon A. Koren, Sierra Swords, Keith W. Nehrke, Gail V.W. Johnson · 2021 · Research Square
33. Therapeutic and immunomodulatory functions of the translocator protein in Alzheimer's disease
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36. Mitophagy and neurodegenerative disease
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37. Sphingolipid metabolism in the regulation of mitophagy: implications in cancer therapy, immune cell function, and neurodegeneration
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38. Mitochondrial Autophagy in Brain
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39. Temporal Interactome Mapping of Human Tau in Drosophila Reveals Progressive Mitochondrial Engagement and Porin/VDAC1-Dependent Modulation of Toxicity
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40. Additional file 5 of Tauopathy-associated tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic model
    Sanjib K Guha, Fischer, Sarah, Johnson, Gail V. W., Nehrke, Keith · 2020 · Figshare
41. Additional file 6 of P62 accumulates through neuroanatomical circuits in response to tauopathy propagation
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42. Additional file 6 of Tauopathy-associated tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic model
    Sanjib K Guha, Fischer, Sarah, Johnson, Gail V. W., Keith W. Nehrke · 2020 · Figshare
43. Additional file 1 of Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer’s disease
    Vicente Roca Agujetas, Barbero-Camps, Elisabet, Cristina de Dios, Petar Podlesniy, Xenia Abadin, Morales, Albert, Montserrat Marı́, Ramón Trullás, Anna Colell · 2021 · Figshare
44. Additional file 3 of Tauopathy-associated tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic model
    Sanjib K Guha, Fischer, Sarah, Johnson, Gail V. W., Nehrke, Keith · 2020 · Figshare
45. Additional file 2 of Tauopathy-associated tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic model
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46. Additional file 4 of Tauopathy-associated tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic model
    Sanjib K Guha, Fischer, Sarah, Johnson, Gail V. W., Nehrke, Keith · 2020 · Figshare
47. Additional file 1 of Tauopathy-associated tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic model
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50. Dysregulation of a novel autophagosome-mitochondria contact contributes to autophagy dysfunction and neurodegeneration in tauopathy
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51. Étude de la composante neuroinflammatoire dans les DFT/SLA
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