18F‐AV‐1451 and CSF T‐tau and P‐tau as biomarkers in Alzheimer's disease

Mattsson, Niklas; Schöll, Michael; Strandberg, Olof; Smith, Ruben; Palmqvist, Sebastian; Insel, Philip S; Hägerström, Douglas; Ohlsson, Tomas; Zetterberg, Henrik; Jögi, Jonas; Blennow, Kaj; Hansson, Oskar

doi:10.15252/emmm.201707809

18F‐AV‐1451 and CSF T‐tau and P‐tau as biomarkers in Alzheimer's disease

To elucidate the relationship between cerebrospinal fluid (CSF) total‐tau (T‐tau) and phosphorylated tau (P‐tau) with the tau PET ligand 18 F‐AV‐1451 in Alzheimer's disease (AD), we examined 30 cognitively healthy elderly (15 with preclinical AD), 14 prodromal AD, and 39 AD dementia patients. CSF…