Testosterone replacement therapy of opioid-induced male hypogonadism improved body composition but not pain perception: a double-blind, randomized, and placebo-controlled trial

Glintborg, Dorte; Vaegter, Henrik Bjarke; Christensen, Louise Lehmann; Bendix, Emma; Graven-Nielsen, Thomas; Andersen, Per Grünwald; Andersen, Marianne

doi:10.1530/eje-19-0979

Testosterone replacement therapy of opioid-induced male hypogonadism improved body composition but not pain perception: a double-blind, randomized, and placebo-controlled trial

Background Hypogonadism is prevalent during opioid treatment, but the effect of testosterone replacement treatment (TRT) on body composition, pain perception, and adrenal function is unclear. Purpose To measure changes in body composition, pain perception, quality of life, and adrenal function af…