Neonatal drug withdrawal
Abstract
Maternal drug use during pregnancy may result in neonatal withdrawal. This statement presents current information about the clinical presentation, differential diagnosis, therapeutic options, and outcome for the offspring associated with intrauterine drug exposure.
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Nicotine has one of the shortest half-lives of drugs used during pregnancy.
“The half-life of nicotine is approximately 2.5 hours in adults15 and 9–11 hours in newborns,16--one of the shortest half-lives of drugs used during pregnancy17.”
From Maternal Smoking during Pregnancy and Newborn Neurobehavior: Effects at 10 to 27 Days (2009) · cites this paper as [17]
Neonatal withdrawal from drugs with longer half-lives (e.g., caffeine) typically lasts less than 10 days.
“Further, neonatal withdrawal from drugs with longer half-lives (e.g., caffeine) typically last less than 10 days17.”
From Maternal Smoking during Pregnancy and Newborn Neurobehavior: Effects at 10 to 27 Days (2009) · cites this paper as [17]
The citation lists haven’t been fetched yet
References 97 · Cited by 234
- Authors
- Committee on Drugs
- Corresponding author
- Committee on Drugs
- Venue
- PEDIATRICS
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 1998-06-01
- Volume
- 101
- Issue
- 6
- Pages
- 1079-1088
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- OpenAlex
- W4205138644
- Cited by
- 234
- References
- 97
- Citations by year
- 2025: 2 · 2024: 1 · 2023: 2 · 2022: 7 · 2021: 2 · 2020: 6 · 2019: 10 · 2018: 3 · 2017: 4 · 2016: 7 · 2015: 6 · 2014: 15 · 2013: 11 · 2012: 18
- FWCI
- 5.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- PEDIATRICS (publishedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy and Medication Impact
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- neonatal drug withdrawal, prenatal drug exposure, drug use in pregnancy, clinical features, differential diagnosis, treatment options, neonatal outcomes
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