The DOI matches its Crossref record; 70 of the 70 references it cites were found in a registry or an index.
Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Statement for Health Professionals From the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association
Abstract
Background. Kawasaki disease is an acute self-limited vasculitis of childhood that is characterized by fever, bilateral nonexudative conjunctivitis, erythema of the lips and oral mucosa, changes in the extremities, rash, and cervical lymphadenopathy. Coronary artery aneurysms or ectasia develop in ∼15% to 25% of untreated children and may lead to ischemic heart disease or sudden death. Methods and Results. A multidisciplinary committee of experts was convened to revise the American Heart Association recommendations for diagnosis, treatment, and long-term management of Kawasaki disease. The writing group proposes a new algorithm to aid clinicians in deciding which children with fever for ≥5 days and ≤4 classic criteria should undergo electrocardiography, receive intravenous gamma globulin (IVIG) treatment, or both for Kawasaki disease. The writing group reviews the available data regarding the initial treatment for children with acute Kawasaki disease, as well for those who have persistent or recrudescent fever despite initial therapy with IVIG, including IVIG retreatment and treatment with corticosteroids, tumor necrosis factor-α antagonists, and abciximab. Long-term management of patients with Kawasaki disease is tailored to the degree of coronary involvement; recommendations regarding antiplatelet and anticoagulant therapy, physical activity, follow-up assessment, and the appropriate diagnostic procedures to evaluate cardiac disease are classified according to risk strata. Conclusions. Recommendations for the initial evaluation, treatment in the acute phase, and long-term management of patients with Kawasaki disease are intended to assist physicians in understanding the range of acceptable approaches for caring for patients with Kawasaki disease. The ultimate decisions for case management must be made by physicians in light of the particular conditions presented by individual patients.
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Citations
Cites
The Treatment of Kawasaki Syndrome with Intravenous Gamma Globulin
Newburger, J. W., Takahashi, M., Burns, J. C., Beiser, A. S., Chung, K. J., Duffy, C. E., Glode, M. P., Mason, W. H., Reddy, V., Sanders, S. P., et al. (1986) · New England Journal of Medicine · doi:10.1056/nejm198608073150601 · Cited by 1,419
Self-citationCyclooxygenase Inhibitors and the Antiplatelet Effects of Aspirin
Catella-Lawson, F., Reilly, M. P., Kapoor, S. C., Cucchiara, A. J., DeMarco, S., Tournier, B., Vyas, S. N., & FitzGerald, G. A. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa003199 · Cited by 1,394
Long-term Consequences of Kawasaki Disease: A 10- to 21-Year Follow-up Study of 594 Patients
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Peters, R. J. G., Mehta, S. R., Fox, K. A. A., Zhao, F., Lewis, B. S., Kopecky, S. L., Diaz, R., Commerford, P. J., Valentin, V., & Yusuf, S. (2003) · Circulation · doi:10.1161/01.cir.0000091201.39590.cb · Cited by 706
Pathology of the Heart in Kawasaki Disease
Fujiwara, H., & Hamashima, Y. (1978) · Pediatrics · doi:10.1542/peds.61.1.100 · Cited by 554
Diagnosis and therapy of Kawasaki disease in children.
Dajani, A. S., Taubert, K. A., Gerber, M. A., Shulman, S. T., Ferrieri, P., Freed, M., Takahashi, M., Bierman, F. Z., Karchmer, A. W., & Wilson, W. (1993) · Circulation · doi:10.1161/01.cir.87.5.1776 · Cited by 526
Self-citationDurongpisitkul, K., Gururaj, V. J., Park, J. M., & Martin, C. F. (1995) · PEDIATRICS · doi:10.1542/peds.96.6.1057 · Cited by 443
Time from symptom onset to treatment and outcomes after thrombolytic therapy
Newby, L. K., Rutsch, W. R., Califf, R. M., Simoons, M. L., Aylward, P. E., Armstrong, P. W., Woodlief, L. H., Lee, K. L., Topol, E. J., & de Werf, F. V. (1996) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(96)00053-8 · Cited by 411
Cited by
EULAR/PReS endorsed consensus criteria for the classification of childhood vasculitides
Ozen, S., Ruperto, N., Dillon, M. J., Bagga, A., Barron, K., Davin, J. C., Kawasaki, T., Lindsley, C., Petty, R. E., Prieur, A. M., et al. (2006) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2005.046300 · Cited by 846
Henderson, L. A., Canna, S. W., Friedman, K. G., Gorelik, M., Lapidus, S. K., Bassiri, H., Behrens, E. M., Ferris, A., Kernan, K. F., Schulert, G. S., et al. (2020) · Arthritis & Rheumatology · doi:10.1002/art.41454 · Cited by 531
Medical Conditions Affecting Sports Participation
Rice, S. G., & and the Council on Sports Medicine and Fitness (2008) · Pediatrics · doi:10.1542/peds.2008-0080 · Cited by 474
Bluemke, D. A., Achenbach, S., Budoff, M., Gerber, T. C., Gersh, B., Hillis, L. D., Hundley, W. G., Manning, W. J., Printz, B. F., Stuber, M., et al. (2008) · Circulation · doi:10.1161/circulationaha.108.189695 · Cited by 461
Henderson, L. A., Canna, S. W., Friedman, K. G., Gorelik, M., Lapidus, S. K., Bassiri, H., Behrens, E. M., Ferris, A., Kernan, K. F., Schulert, G. S., et al. (2021) · Arthritis & Rheumatology · doi:10.1002/art.41616 · Cited by 412
Metadata
- Authors
- Newburger, J. W., Takahashi, M., Gerber, M. A., Gewitz, M. H., Tani, L. Y., Burns, J. C., Shulman, S. T., Bolger, A. F., Ferrieri, P., Baltimore, R. S., Wilson, W. R., Baddour, L. M., Levison, M. E., Pallasch, T. J., Falace, D. A., & Taubert, K. A.
- Venue
- Pediatrics
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 2004-12-01
- Volume
- 114
- Issue
- 6
- Pages
- 1708-1733
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- OpenAlex
- W2101554991
- Cited by
- 1,431
- References
- 70
- FWCI
- 33.32
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Statement for Health Professionals From the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. https://app.cochat.ai/papers/10.1542/peds.2004-2182
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- Newburger, J. W., Takahashi, M., Gerber, M. A., Gewitz, M. H., Tani, L. Y., Burns, J. C., Shulman, S. T., Bolger, A. F., Ferrieri, P., Baltimore, R. S., Wilson, W. R., Baddour, L. M., Levison, M. E., Pallasch, T. J., Falace, D. A., & Taubert, K. A. (2004). Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Statement for Health Professionals From the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Pediatrics. https://doi.org/10.1542/peds.2004-2182
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
