Prevalence and correlates of depressed mood among youth with diabetes: the SEARCH for Diabetes in Youth study
Abstract
OBJECTIVE.The objective of this study was to determine if depressed mood among youth with diabetes was associated with type and duration of diabetes, mean glycosylated hemoglobin (HbA1c) level, and the frequency of diabetic ketoacidosis (DKA) and hypoglycemic episodes, hospitalizations, and emergency department (ED) visits. METHODS.A total of 2672 youth (aged 10–21 years) who had diabetes for a mean duration of 5 years completed a SEARCH study visit, in which their HbA1c was measured and information about their demographic characteristics, diabetes type and duration, and episodes of DKA, hypoglycemia, hospitalizations, and ED visits over the previous 6 months was collected. Their level of depressed mood was measured using the Center for Epidemiologic Studies Depression Scale (CES-D). RESULTS.Among these youth, 14% had mildly (CES-D 16–23) and 8.6% had moderately or severely (CES-D ≥24) depressed mood. Females had a higher mean CES-D score than males. After adjusting for demographic factors, and duration of diabetes, we found the prevalence of depressed mood to be higher among males with type 2 diabetes than those with type 1 diabetes and to be higher among females with comorbidities than those without comorbidities. Higher mean HbA1c and frequency of ED visits were associated with depressed mood. The prevalence of depressed mood among youth with diabetes was similar to that of published estimates of depressed mood among youth without diabetes. CONCLUSIONS.Physicians and other health care professionals should consider screening youth with diabetes for depressed mood in clinical settings, particularly youth with poor glycemic control, those with a history of frequent ED visits, males with type 2 diabetes, and females with comorbidities.
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Clinically significant psychopathology in people with diabetes varies by diagnostic category, and some diagnoses are much more common than in people without diabetes.
“Prevalence of clinically significant psychopathology in PWD ranges across diagnostic categories, and some diagnoses are considerably more common in PWD than in those without the disease (47–52).”
From Psychosocial care for people with diabetes: a position statement of the American Diabetes Association (2016) · cites this paper as [52]
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References 48 · Cited by 329
- Authors
- Lawrence, J. M., Standiford, D. A., Loots, B., Klingensmith, G. J., Williams, D. E., Ruggiero, A., Liese, A. D., Bell, R. A., Waitzfelder, B. E., McKeown, R. E., & Study, F. T. S. F. D. I. Y.
- Affiliations
- Kaiser Permanente (US)
- Cincinnati Children's Hospital Medical Center (US)
- Seattle Children's Hospital (US)
- Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Denver, Colorado
- Centers for Disease Control and Prevention (US)
- Wake Forest University Health Sciences (US)
- University of South Carolina (US)
- Pacific Health Research and Education Institute (US)
- ORCID
- Venue
- Pediatrics
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 2006-04-01
- Volume
- 117
- Issue
- 4
- Pages
- 1348-1358
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- OpenAlex
- W2105357111
- Cited by
- 329
- References
- 48
- Citations by year
- 2026: 7 · 2025: 6 · 2024: 18 · 2023: 12 · 2022: 18 · 2021: 19 · 2020: 21 · 2019: 22 · 2018: 21 · 2017: 23 · 2016: 12 · 2015: 21 · 2014: 21 · 2013: 17 · 2012: 20
- FWCI
- 9.09
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- PEDIATRICS (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- Centers for Disease Control and Prevention
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- depressive mood, youth with diabetes, type 1 diabetes, type 2 diabetes, glycemic control, HbA1c, diabetic ketoacidosis, hypoglycemia, emergency department visits, hospitalization, depression screening, sex differences, comorbidities, SEARCH for Diabetes in Youth
- MeSH terms
- Adolescent, Adult, Child, Depression, Diabetes Mellitus, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Emergency Service, Hospital, Female, Glycated Hemoglobin, Hospitalization, Humans, Hypoglycemia, Male, Prevalence, Diabetic Ketoacidosis
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