Clostridium difficile Infection in Infants and Children

Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA)

Cohen, S. H., Gerding, D. N., Johnson, S., Kelly, C. P., Loo, V. G., McDonald, L. C., Pépin, J., & Wilcox, M. H. (2010) · Infection Control and Hospital Epidemiology · doi:10.1086/651706 · Cited by 2,931

A Predominantly Clonal Multi-Institutional Outbreak ofClostridium difficile–Associated Diarrhea with High Morbidity and Mortality

Loo, V. G., Poirier, L., Miller, M. A., Oughton, M., Libman, M., Michaud, S., Bourgault, A., Nguyen, T., Frenette, C. H., Kelly, M., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa051639 · Cited by 1,962

A Comparison of Vancomycin and Metronidazole for the Treatment of Clostridium difficile-Associated Diarrhea, Stratified by Disease Severity

Zar, F. A., Bakkanagari, S. R., Moorthi, K. M. L. S. T., & Davis, M. B. (2007) · Clinical Infectious Diseases · doi:10.1086/519265 · Cited by 1,247

Comparison of Vancomycin, Teicoplanin, Metronidazole, and Fusidic Acid for the Treatment of Clostridium difficile--Associated Diarrhea

Wenisch, C., Parschalk, B., Hasenhundl, M., Hirschl, A. M., & Graninger, W. B. (1996) · Clinical Infectious Diseases · doi:10.1093/clinids/22.5.813 · Cited by 500

The Intestinal Microflora of Infants: Composition of Fecal Flora in Breast‐Fed and Bottle‐Fed Infants

Benno, Y., Sawada, K., & MITSUOKA, T. (1984) · Microbiology and Immunology · doi:10.1111/j.1348-0421.1984.tb00754.x · Cited by 432

European Society of Clinical Microbiology and Infectious Diseases (ESCMID): Data review and recommendations for diagnosing Clostridium difficile-infection (CDI)

Crobach, M. J. T., Dekkers, O. M., Wilcox, M. H., & Kuijper, E. J. (2009) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2009.03098.x · Cited by 409

Isolation rates and toxigenic potential of Clostridium difficile isolates from various patient populations

Viscidi, R. P., Willey, S., & Bartlett, J. G. (1981) · Gastroenterology · doi:10.1016/0016-5085(81)90644-2 · Cited by 404

Epidemiological Features of Clostridium difficile-Associated Disease Among Inpatients at Children's Hospitals in the United States, 2001–2006

Kim, J., Smathers, S. A., Prasad, P. A., Leckerman, K. H., Coffin, S. E., & Zaoutis, T. E. (2008) · PEDIATRICS · doi:10.1542/peds.2008-0469 · Cited by 319

Asymptomatic Colonization by Clostridium difficile in Infants: Implications for Disease in Later Life

Jangi, S., & LaMont, J. T. (2010) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e3181d29767 · Cited by 306

Severe Clostridium difficile-Associated Disease in Populations Previously at Low Risk: Four States, 2005

&NA; (2006) · The Pediatric Infectious Disease Journal · doi:10.1097/01.inf.0000202057.19407.4d · Cited by 271

Bacterial Infections of the Small and Large Intestine

Bernard, R., & Nicholson, M. R. (2021) · Springer eBooks · doi:10.1007/978-3-030-80068-0_15 · Cited by 2

High Prevalence of Chemical and Microbiological Drinking Water Contaminants in Households with Infants Enrolled in a Birth Cohort—Piura, Peru, 2016

Delahoy, M. J., Hubbard, S., Mattioli, M. C. M., Culquichicón, C., Knee, J., Brown, J. M., Cabrera, L. Z., Barr, D. B., Ryan, P. B., Lescano, A. G., et al. (2022) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.22-0098 · Cited by 4

A Comparison of Pathogen Detection and Risk Factors among Symptomatic Children with Gastroenteritis Compared with Asymptomatic Children in the Post-rotavirus Vaccine Era

Lee, B. R., Harrison, C. J., Hassan, F., Sasidharan, A., Moffatt, M. E., Weltmer, K., Payne, D. C., Wikswo, M. E., Parashar, U. D., & Selvarangan, R. (2023) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2023.113551 · Cited by 2

Probiotics for the prevention of pediatric antibiotic-associated diarrhea: Summary of a Cochrane review

Bethel, M. (2019) · EXPLORE · doi:10.1016/j.explore.2019.07.001 · Cited by 2

Bacterial, Viral, and Toxic Causes of Diarrhea, Gastroenteritis, and Anorectal Infections

Cohen, M. B. (2015) · Wiley eBooks · doi:10.1002/9781118512074.ch62 · Cited by 2

C. difficile-infection and microbyota in newborns: resolved and outstanding issues

Mazankova, L. N., Perlovskaya, S. G., & Rubalchenko, O. V. (2021) · CHILDREN INFECTIONS · doi:10.22627/2072-8107-2021-20-3-39-47 · Cited by 1

An Evaluation of Enteropathogen-Specific Disease Severity and Duration in Children With Acute Gastroenteritis

Roskind, C. G., Schnadower, D., Rogers, A. J., Casper, T. C., Tarr, P. I., Levine, A. C., Bhatt, S. R., Gouin, S., Mahajan, P., Vance, C., et al. (2025) · Pediatric Emergency Care · doi:10.1097/pec.0000000000003459 · Cited by 1

Impact of gastrointestinal multiplex PCR on the diagnosis, clinical correlation, and antimicrobial stewardship in pediatric acute gastroenteritis

AlHazimi, A., AlQahtani, A., Alsahli, A. A., AlOtaibi, A., Sheikho, M., Alzighaibi, R., & Qadrah, B. H. A. (2026) · Frontiers in Pediatrics · doi:10.3389/fped.2026.1735228 · Cited by 1

Clostridium difficile Bacteremia in a Neonate

Bergamo, D. F. (2016) · Clinical Pediatrics · doi:10.1177/0009922816664068 · Cited by 1

Detection of toxigenic Clostridium difficile in paediatric patients

Falces‐Romero, I., Troyano-Hernáez, P., Bujalance, S. G., Baquero‐Artigao, F., Mellado, M. J., & García‐Rodríguez, J. (2018) · Enfermedades infecciosas y microbiologia clinica (English ed ) · doi:10.1016/j.eimce.2018.04.006 · Cited by 1

Approach to the Diagnosis and Management of Gastrointestinal Tract Infections

Yi, J., & Shane, A. L. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-40181-4.00055-4 · Cited by 2

Detection of Clostridioides difficile toxin B gene: benefits of identifying gastrointestinal pathogens by mPCR assay in the diagnosis of diarrhea in pediatric patients

Byun, J., Yong, D., & Kim, H. (2022) · BMC Infectious Diseases · doi:10.1186/s12879-022-07104-z · Cited by 1

Diarrhea

Gurram, B. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-76174-1.00014-6 · Cited by 2

Effect of Metronidazole in Infants with Bowel Habit Change: Irrelative to theClostridium difficileColonization

Kim, E. J., Lee, S. H., Tchah, H., & Ryoo, E. (2017) · Pediatric Gastroenterology Hepatology & Nutrition · doi:10.5223/pghn.2017.20.1.47 · Cited by 1

Application of a Multiplex Polymerase Chain Reaction Test for Diagnosing Bacterial Enteritis in Children in a Real-Life Clinical Setting

Lee, H. W., Han, S. B., & Rhim, J. W. (2021) · Children · doi:10.3390/children8070538 · Cited by 1

No Small Thing: Clinical Implications of Rapid Syndromic Panel-Based Diagnostic Testing in Children

NGUYEN, S., & Same, R. (2021) · Clinical Microbiology Newsletter · doi:10.1016/j.clinmicnews.2021.08.001 · Cited by 1

Anti-Acid Drugs: Adverse Effects

Levy, E. I., Kindt, S., Simon, M., & Vandenplas, Y. (2022) · Springer eBooks · doi:10.1007/978-3-030-99067-1_23 · Cited by 1

The microbiota as target for therapeutic intervention in pediatric intestinal diseases

Vecchio, A. L., & Guarino, A. (2016) · Wiley eBooks · doi:10.1002/9781118982907.ch31 · Cited by 1

Rzekomobłoniaste zapalenie jelit u dzieci

Mielniczuk, K., & Czerwionka‐Szaflarska, M. (2014) · Pediatria Polska · doi:10.1016/j.pepo.2014.12.001

Clostridium difficile Infection Among US Children

(2014) · AAP Grand Rounds · doi:10.1542/gr.32-2-20

Epidemiology of Infection Caused by Clostridium difficile

Štěpánová, J., & Tomášková, H. (2014) · Hygiena · doi:10.21101/hygiena.a1283

Probiotics Use in Infectious Disease (Respiratory, Diarrhea, and Antibiotic-Associated Diarrhea)

Guandalini, S., & Sansotta, N. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804024-9.00033-1

The importance of probiotics in antibiotic associated diarrhea

Duman, M., & Çağlar, A. (2017) · Journal of Dr Behcet Uz Children s Hospital · doi:10.5222/buchd.2017.001

Early success seen with fecal microbiota transplantation for C. difficile infections

Schutze, G. E., & Maldonado, Y. (2014) · AAP News · doi:10.1542/aapnews.2014357-18

Update in Pediatric Infectious Disease

Chatterjee, A., & Gogoi, M. (2018) · Springer eBooks · doi:10.1007/978-3-319-58027-2_13

C. difficile Infection in Children: What’s New?

Hellmann, J., & Mallon, D. P. (2018) · Current Treatment Options in Pediatrics · doi:10.1007/s40746-018-0124-1

Peer Review #3 of "Applying fecal microbiota transplantation (FMT) to treat recurrent Clostridium difficile infections (rCDI) in children (v0.1)"

(2018) · PeerJ · doi:10.7287/peerj.4663v0.1/reviews/3

Peer Review #2 of "Applying fecal microbiota transplantation (FMT) to treat recurrent Clostridium difficile infections (rCDI) in children (v0.1)"

(2018) · PeerJ · doi:10.7287/peerj.4663v0.1/reviews/2

Peer Review #2 of "Applying fecal microbiota transplantation (FMT) to treat recurrent Clostridium difficile infections (rCDI) in children (v0.2)"

(2018) · PeerJ · doi:10.7287/peerj.4663v0.2/reviews/2

Acute Onset Rectal Prolapse with a Pseudomembranous Covering

Tomioka, Y., Okata, Y., Bitoh, Y., Tsugawa, J., & Nishijima, E. (2019) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2019.08.044

Response to

Kociolek, L. K., Davidovics, Z. H., Kahn, S. A., & Kellermayer, R. (2019) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000002388

Impact of the 3‐day rule for stool culture in a children's hospital

Taniyama, Y., Shoji, K., Hashimoto, M., Ishuguro, A., & Miyairi, I. (2020) · Pediatrics International · doi:10.1111/ped.14100

Clinical and therapeutical aspects of antibiotic-associated diarrhea

Disciplina Pediatrie, U. D. M. Ş. F. „. T. P., Ignat, A., Mucenica, I. M., Disciplina Pediatrie, U. D. M. Ş. F. „. T. P., Druică, A., Disciplina Pediatrie, U. D. M. Ş. F. „. T. P., Miron, O. T., Disciplina Pediatrie, U. D. M. Ş. F. „. T. P., Duceac, L. D., Dragan, F., et al. (2016) · Romanian Medical Journal · doi:10.37897/rmj.2016.1.5

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Peer Review #1 of "Applying fecal microbiota transplantation (FMT) to treat recurrent Clostridium difficile infections (rCDI) in children (v0.1)"

(2018) · PeerJ · doi:10.7287/peerj.4663v0.1/reviews/1

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Clostridioides-difficile-Infektion bei Kindern

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Clostridioides difficile infection in children hospitalised in Motol University Hospital

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Infezione da Clostridioides difficile nel neonato e nel lattante: una malattia... “difficile”!

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Clinical impact of toxin detection in children with PCR-confirmed Clostridioides difficile infection

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Age-related clinical and therapeutic differences during a hospital outbreak of Clostridioides difficile infection in Colombia

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Factores de riesgo asociados a infección por Clostridioides difficile en pacientes pediátricos

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Decreasing treatment for postoperative Clostridioides difficile infection in Pediatric Surgery patients

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Clinical Characteristics of Pediatric Clostridioides difficile Infection at a Children's Hospital

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Прогностическая значимость полуколичественного уровня токсинов A/B у детей с Clostridioides difficile-ассоциированной инфекцией

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Clostridioides difficile infections and beyond: molecular epidemiology, One Health transmission chains, under-surveilled regions, and the next generation of diagnostics, therapeutics, and vaccines

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Policy offers recommendations on managing C. difficile infections in pediatric patients

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Clinical Guideline Highlights for the Hospitalist: Clostridium difficile Infections in Children

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Clostridium difficile Infection

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Clostridioides difficile Infection in Children—An Update

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Clostridium difficile in paediatric populations

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