The DOI matches its Crossref record.
IDIOPATHIC HYPERGLYCINEMIA AND HYPERGLYCINURIA: A NEW DISORDER OF AMINO ACID METABOLISM. I
Abstract
Observations are reported of a patient afflicted with a disease previously unknown to us. The outstanding features of the syndrome are: onset in the neonatal period of episodes of vomiting, lethargy and ketosis; neutropenia; periodic thrombocytopenia; hypogammaglobulinemia; hyperglycinemia and hyperglycinuria; developmental retardation; and intolerance of protein of more than approximately 0.5 gm/kg of body weight/day and of protein hydrolysate and of leucine.
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Citations
Cited by
The effects of extracellular pH on immune function
Lardner, A. (2001) · Journal of Leukocyte Biology · doi:10.1189/jlb.69.4.522 · Cited by 864
Glycine cleavage system: reaction mechanism, physiological significance, and hyperglycinemia
KIKUCHI, G., MOTOKAWA, Y., YOSHIDA, T., & HIRAGA, K. (2008) · Proceedings of the Japan Academy, Series B · doi:10.2183/pjab.84.246 · Cited by 375
Head, P. E., Myung, S., Chen, Y., Schneller, J. L., Wang, C., Duncan, N., Hoffman, P., Chang, D., Gebremariam, A., Gucek, M., et al. (2022) · Science Translational Medicine · doi:10.1126/scitranslmed.abn4772 · Cited by 52
Metadata
- Authors
- Childs, B., Nyhan, W. L., Borden, M., Bard, L., & Cooke, R. E.
- Venue
- Pediatrics
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 1961-04-01
- Volume
- 27
- Issue
- 4
- Pages
- 522-538
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- OpenAlex
- W1677893931
- Cited by
- 255
- References
- 0
- FWCI
- 10.19
- Type
- journal article
- Language
- en
- Open access
- closed
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- This page
- CoChat. (2026). Citation check: IDIOPATHIC HYPERGLYCINEMIA AND HYPERGLYCINURIA: A NEW DISORDER OF AMINO ACID METABOLISM. I. https://app.cochat.ai/papers/10.1542/peds.27.4.522
- The paper
- Childs, B., Nyhan, W. L., Borden, M., Bard, L., & Cooke, R. E. (1961). IDIOPATHIC HYPERGLYCINEMIA AND HYPERGLYCINURIA: A NEW DISORDER OF AMINO ACID METABOLISM. I. Pediatrics. https://doi.org/10.1542/peds.27.4.522
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
