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A Simple Estimate of Glomerular Filtration Rate in Children Derived From Body Length and Plasma Creatinine
Abstract
Based on statistical analysis of data in 186 children, a formula was derived which allows accurate estimation of glomerular filtration rate (GFR) from plasma creatinine and body length (GFR (ml/min/1.73 sq m) = 0.55 length (cm)/Pcr (mg/dl). Its application to clearance data in a separate group of 223 children reveals excellent agreement with GFR estimated by the Ccr (r = .935) or Cin (r = .905). This formula should be useful for adjusting dosages of drugs excreted by the kidney and detecting significant changes in renal function.
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Citations
Cited by
Epidemiology of Acute Kidney Injury in Critically Ill Children and Young Adults
Kaddourah, A., Basu, R. K., Bagshaw, S. M., & Goldstein, S. L. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1611391 · Cited by 1,075
Cystatin C as a marker of GFR—history, indications, and future research
Filler, G., Bökenkamp, A., Hofmann, W., Le Bricon, T., Martínez-Brú, C., & Grubb, A. (2005) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2004.09.025 · Cited by 734
The definition of acute kidney injury and its use in practice
Thomas, M. E., Blaine, C., Dawnay, A., Devonald, M. A. J., Ftouh, S., Laing, C., Latchem, S., Lewington, A., Milford, D. V., & Ostermann, M. (2015) · Kidney International · doi:10.1038/ki.2014.328 · Cited by 722
Calzavacca, P., Licari, E., & Bellomo, R. (2010) · Surgical Intensive Care Medicine · doi:10.1007/978-0-387-77893-8_38 · Cited by 533
Johnson, T. N., Rostami-Hodjegan, A., & Tucker, G. T. (2006) · Clinical Pharmacokinetics · doi:10.2165/00003088-200645090-00005 · Cited by 530
Metadata
- Authors
- Schwartz, G. J., Haycock, G. B., Edelmann, C. M., & Spitzer, A.
- Venue
- Pediatrics
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 1976-08-01
- Volume
- 58
- Issue
- 2
- Pages
- 259-263
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- OpenAlex
- W1960255425
- Cited by
- 2,379
- References
- 0
- FWCI
- 5.37
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Schwartz, G. J., Haycock, G. B., Edelmann, C. M., & Spitzer, A. (1976). A Simple Estimate of Glomerular Filtration Rate in Children Derived From Body Length and Plasma Creatinine. Pediatrics. https://doi.org/10.1542/peds.58.2.259
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
