The DOI matches its Crossref record.
Mast Cells in Hemangiomas and Vascular Malformations
Abstract
Common pediatric vascular birthmarks, classified as hemangiomas or malformations, were analyzed for the presence of mast cells. Hemangiomas in the proliferative phase contained large numbers of mast cells (27 ± 15 cells/high-power field [HPF]) in comparison with hemangiomas in the involuting phase (2.6 ± 2.9), vascular malformations (1.7 ± 3.2), and normal skin (5.0 ± 1.0). Inasmuch as hemangiomas are characterized by endothelial proliferation and increased numbers of mast cells, these data raise the possibility that mast cells may have an important role in the formation and/or maintenance of these lesions.
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Cited by
Cellular markers that distinguish the phases of hemangioma during infancy and childhood.
Takahashi, K., Mulliken, J. B., Kozakewich, H. P., Rogers, R. A., Folkman, J., & Ezekowitz, R. A. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117241 · Cited by 648
Self-citationTumor interactions with the vasculature: angiogenesis and tumor metastasis
Blood, C. (1990) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/0304-419x(90)90014-r · Cited by 593
Bruckner, A. L., & Frieden, I. J. (2003) · Journal of the American Academy of Dermatology · doi:10.1067/mjd.2003.200 · Cited by 381
Hemangiomas and Vascular Malformations of Infancy and Childhood
Fishman, S. J., & Mulliken, J. B. (1993) · Pediatric Clinics of North America · doi:10.1016/s0031-3955(16)38656-4 · Cited by 307
Self-citationOn Scleroderma: Mast Cells, Endothelial Cells, and Fibroblasts
Claman, H. N. (1989) · JAMA · doi:10.1001/jama.1989.03430090068035 · Cited by 112
Metadata
- Authors
- Glowacki, J., & Mulliken, J. B.
- Venue
- Pediatrics
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 1982-07-01
- Volume
- 70
- Issue
- 1
- Pages
- 48-51
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- OpenAlex
- W4206557022
- Cited by
- 247
- References
- 0
- FWCI
- 8.29
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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