The DOI matches its Crossref record.
Severe hypokalemia secondary to abuse of β-adrenergic agonists in a pediatric patient: Case report
Open accessAbstract
ABSTRACT This study reports a case of a 13-year-old male with a 3-year history of severe and intermittent hypokalemia episodes of unknown origin, requiring admission to the intensive care unit (ICU) for long QT syndrome (LQTS), finally diagnosed of redistributive hypokalemia secondary to the abuse of β-adrenergic agonists in the context of a probable factitious disorder.
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“Although such bronchodilators can be therapeutically useful—for example, in promoting alveolar fluid clearance in acute respiratory distress syndrome—because of their effects on sodium ion transport [27,28], their inappropriate use or overuse in susceptible individuals can lead to profound hypokalemia and paralysis [43].”
From Thyrotoxic Hypokalemic Periodic Paralysis: Pathophysiological Mechanisms (2025) · cites this paper as [43]
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Research works printed but not linked: 16
- Singhi S, 1996, Hypokalemia in a pediatric intensive care unit, Indian Pediatr, 33, 9
- Somers M, 2018, Hypokalemia in children, UpToDate
- Wills BK, 2015, Recalcitrant Supraventricular Tachycardia: Occult Albuterol Toxicity Due to a Factitious Disorder, J Emerg Med, 49, 436, 10.1016/j.jemermed.2015.05.007 · DOI
- Daly K, 2013, Hypokalemia and Hyperkalemia in Infants and Children: Pathophysiology and Treatment, J Pediatr Health Care, 27, 486, 10.1016/j.pedhc.2013.08.003 · DOI
- De Sequera Ortíz P, 2019, Trastornos del potasio
- Cummings BM, 2014, Potassium abnormalities in a pediatric intensive care unit: frequency and severity, J Intensive Care Med, 29, 269, 10.1177/0885066613491708 · DOI
- Mount DB, 2007, Disorders of potassium balance, 547
- Schaefer TJ, 2005, Disorders of potassium, Emerg Med Clin North Am, 23, 723, 10.1016/j.emc.2005.03.016 · DOI
- Glatstein MM, 2013, Unintentional oral beta agonist overdose: case report and review of the literature, Am J Ther, 20, 311, 10.1097/MJT.0b013e3182002f2d · DOI
- Hoikka MH, 2013, Acute poisoning in children under the age of six: a two-decade study of hospital admissions and trends, Acta Paediatr, 102, e329, 10.1111/apa.12238 · DOI
- Martínez Mengual L, 2005, Taquicardia paroxística supraventricular por sobreingesta de salbutamol, Bol Pediatr, 45, 70
- Yates GP, 2016, Factitious disorder: A systematic review of 455 cases in the professional literature, Gen Hosp Psychiatry, 41, 20, 10.1016/j.genhosppsych.2016.05.002 · DOI
- Marzuillo P, 2016, From oliguria to urinary incontinence: a case of Munchausen's syndrome in an adolescent boy, Int J Adolesc Med Health, 30, 10.1515/ijamh-2016-0039 · DOI
- Bolat N, 2017, Factitious Disorder Presenting with Stuttering in Two Adolescents: The Importance of Psychoeducation, Noro Psikiyatri Ars, 54, 87, 10.5152/npa.2017.12349 · DOI
- Abeln B, 2018, An Overview of Munchausen Syndrome and Munchausen Syndrome by Proxy, Nurs Clin North Am, 53, 375, 10.1016/j.cnur.2018.04.005 · DOI
- Tozzo P, 2018, Munchausen Syndrome by Proxy: balancing ethical and clinical challenges for healthcare professionals Ethical consideration in factitious disorders, Clin Ter, 169, e129
Cited by
Sorted by citations
Thyrotoxic Hypokalemic Periodic Paralysis: Pathophysiological Mechanisms
Qing, G., Zakaria, W. N. A., Rom, F. Z. M., Nik, W. N. F. H. W., Zulkeflee, H. A., & Rahim, S. N. A. (2025) · Endocrinology and Metabolism · doi:10.3803/enm.2025.2554 · Cited by 5
“In general, hypokalemia can be categorized into three mechanisms: renal potassium wasting, extrarenal losses (e.g., diarrhea), and transcellular redistribution [38,43].”
Metadata
- Authors
- Aliaga, C. A., Arizon, L. F. D., Bermúdez, R. M., Castán, J. A. B., & Santandreu, A. V.
- Affiliations
- Fundació Puigvert, España
- Puigvert Foundation (ES)
- Venue
- Brazilian Journal of Nephrology
- Publisher
- FapUNIFESP (SciELO)
- Published
- 2020-06
- Volume
- 42
- Issue
- 2
- Pages
- 250-253
- ISSN
- 0101-2800 (ISSN-L)
- 2175-8239
- PMC
- PMC7427655
- OpenAlex
- W2947000693
- Cited by
- 5
- References
- 0
- Citations by year
- 2025: 1 · 2022: 2 · 2021: 1 · 2020: 1
- FWCI
- 0.74
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- Locations
- Brazilian Journal of Nephrology (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Americanae (AECID Library) (publishedVersion, other-oa)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Nephrology › Potassium and Related Disorders
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Pharmacological Effects and Assays
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Sedative Agents
- Keywords
- hypokalemia, beta-adrenergic agonists, drug abuse, long QT syndrome, factitious disorder, pediatric patients, electrolyte imbalance
- MeSH terms
- Adolescent, Adrenergic beta-Agonists, Albuterol, Factitious Disorders, Humans, Hypokalemia, Long QT Syndrome, Male, Potassium, Recurrence, Drug Overdose
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