Incidence of acne vulgaris in young adult users of protein-calorie supplements in the city of Joao Pessoa-PB
Open accessAbstract
BACKGROUND: Based on personal observations of dermatologists, nutritionists and patients, a new problem emerges in the gyms: development and exacerbation of acne in users of whey protein, which is a protein derived from cow's milk. Whey Protein extract contains growth factors that may be related to acne. Its purity and composition are not fully known and there is no scientific research on its potential to cause acne. OBJECTIVES: Assess the relationship between the use of proteincalorie supplements and onset or exacerbation of acne vulgaris in young adults in the city of João Pessoa. METHODS: Descriptive observational study conducted in gyms and in a dermatology clinic. Each participant was examined for acne on three occasions and followed for 60 days. RESULTS: 30 patients were examined. Onset or exacerbation of acneiform lesions were observed (p <0.0005). The effect was more prominent in females and in individuals without current acne and no family history of acne. CONCLUSION: This study showed the onset of acne with the progressive use of protein-calorie supplementation, in a two-month period. It is suggested that this type of supplementation be discouraged.
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35.7% (10/28) of observational studies exclusively commented on the association between dairy and acne.
“Overall, 35.7% (10/28) exclusively commented on the association between dairy and acne (Table II),24, 25, 26, 27, 28, 29, 30, 31, 32, 33”
From Diet and acne: A systematic review (2022) · cites this paper as [28]
The Introduction identifies whey protein as derived from milk, and the Discussion links protein-calorie supplement use with acne. But the study did not exclusively examine dairy: the Results include participants using other protein supplements. The 35.7% (10/28) figure describes the citing paper’s collection of studies, not a finding attributed to this individual study. (LLM, conf=0.87)
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Research works printed but not linked: 13
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- [3]Thiboutot DM Strauss JS Diet and acne Arch Dermatol 2002 138 1591 1592 12472347
- [5]Zaenglein AL Graber EM Thiboutot DM Strauss JS Acne vulgaris and acneiform eruptions Wolff K Goldsmith LA Katz SI Gilchrest BA Paller AS Leffell DJ Fitzpatrick's Dermatology in General Medicine New York McGraw-Hill Medical 7:609 7:703 2008
- [6]Marshall K Therapeutic Applications of Whey Protein Altern Med Rev 2000 9 136 156 15253675
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- [13]Adebamowo CA Spiegelman D Danby FW Frazier AL Willett WC Holmes MD High school dietary dairy intake and teenage acne J Am Acad Dermatol 2005 52 207 214 15692464
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- [15]Adebamowo CA Spiegelman D Berkey CS Danby FW Rockett HH Colditz GA Willett WC et al Milk consumption and acne in teenaged boys J Am Acad Dermatol 2008 58 787 793 18194824 PMC4391699
- [16]Melnik BC Evidence for acne-promoting effects of milk and other insulinotropic dairy products Nestle Nutr Workshop Ser Pediatr Program 2011 67 131 145 21335995
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Linking diet to acne metabolomics, inflammation, and comedogenesis: an update
Melnik, B. (2015) · Clinical, Cosmetic and Investigational Dermatology · doi:10.2147/ccid.s69135 · Cited by 259 · see citing works
Diet and acne: A systematic review
Meixiong, J., Ricco, C., Vasavda, C., & Ho, B. K. (2022) · JAAD International · doi:10.1016/j.jdin.2022.02.012 · Cited by 108 · see citing works
- Authors
- Pontes, T. D. C., Fernandes Filho, G. M. C., Trindade, A. D. S. P., & Sobral Filho, J. F.
- Affiliations
- Universidade Federal da Paraíba (BR)
- Federal University of Paraiba, Brazil
- Venue
- Anais Brasileiros de Dermatologia
- Publisher
- FapUNIFESP (SciELO)
- Published
- 2013-12
- Volume
- 88
- Issue
- 6
- Pages
- 907-912
- ISSN
- 0365-0596 (ISSN-L)
- PMC
- PMC3900340
- OpenAlex
- W1967387023
- Cited by
- 41
- References
- 0
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 7 · 2023: 2 · 2022: 7 · 2021: 4 · 2020: 3 · 2019: 5 · 2017: 4 · 2016: 3 · 2015: 2
- FWCI
- 1.81
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by-nc
- Locations
- Anais Brasileiros de Dermatologia (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
- Americanae (AECID Library) (submittedVersion, cc-by-nc)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Universidade Federal da Paraíba
- Topics
- Health Sciences › Medicine › Dermatology › Acne and Rosacea Treatments and Effects
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Dermatology › Dermatological and COVID-19 studies
- Keywords
- acne, whey protein, young adults, gym members, acne exacerbation, sex differences, João Pessoa
- MeSH terms
- Whey Proteins, Acne Vulgaris, Adolescent, Adult, Brazil, Dietary Proteins, Epidemiologic Methods, Female, Humans, Male, Middle Aged, Milk Proteins, Severity of Illness Index, Sex Factors, Time Factors, Sex Distribution, Dietary Supplements, Young Adult
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