The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Dissolution profile evaluation of solid pharmaceutical forms containing chloramphenicol marketed in Brazil
Open accessAbstract
The dissolution profile for solid pharmaceutical forms containing chloramphenicol 250 mg available in Brazil was determined using a method from the American Pharmacopoeia (United States Pharmacopoeia, 2004) and then compared. Two different methods of dissolution profile comparison were used: ANOVA, and an independent model. Differences between the formulations were reflected in the dissolution profiles. The presence of metastable polymorphs or amorphous forms of chloramphenicol palmitate might be responsible for variations in the concentration of the drug observed within formulations.
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“For that reason, the importance of dissolution tests and dissolution profile for the establishment of pharmaceutical equivalence must be highlighted 3, 4 .”
From Evaluation and comparison of in-vitro dissolution profiles for different brands of amoxicillin capsules (2013) · cites this paper as [4]
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“The presences of generic products that are not interchangeable with that of the innovator and/or with each others have been reported 4, 6, 8-10 .”
From Evaluation and comparison of in-vitro dissolution profiles for different brands of amoxicillin capsules (2013) · cites this paper as [4]
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“However different reported studies over the last years revealed that marketed products with the same amount of active ingredient exhibit marked differences in their therapeutic responses.”
From Evaluation and comparison of in-vitro dissolution profiles for different brands of amoxicillin capsules (2013) · cites this paper as [4]
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Citations
Cites
Dissolution Testing as a Prognostic Tool for Oral Drug Absorption: Immediate Release Dosage Forms
Dressman, J. B., Amidon, G. L., Reppas, C., & Shah, V. P. (1998) · Pharmaceutical Research · doi:10.1023/a:1011984216775 · Cited by 1,097
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Cited by
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Kassaye, L., & Genete, G. (2013) · African Health Sciences · doi:10.4314/ahs.v13i2.25 · Cited by 80
Metadata
- Authors
- Ferraz, H. G., Carpentieri, L. N., & Watanabe, S. P.
- Affiliations
- Universidade de São Paulo (BR)
- Universidade de Brasília, Brasil
- Venue
- Brazilian Archives of Biology and Technology
- Publisher
- FapUNIFESP (SciELO)
- Published
- 2007-01
- Volume
- 50
- Issue
- 1
- Pages
- 57-65
- ISSN
- 1516-8913 (ISSN-L)
- OpenAlex
- W2104593902
- Cited by
- 18
- References
- 1
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 2 · 2021: 3 · 2018: 1 · 2017: 1 · 2013: 3 · 2012: 5
- FWCI
- 0.26
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by-nc
- Locations
- Brazilian Archives of Biology and Technology (publishedVersion, cc-by-nc)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
- Americanae (AECID Library) (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, other-oa)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Drug Solubulity and Delivery Systems
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical Methods in Pharmaceuticals
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pharmaceutical Quality and Counterfeiting
- Keywords
- chloramphenicol, chloramphenicol palmitate, dissolution profile, dissolution profile comparison, polymorphism, amorphous drug, pharmaceutical quality control
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