Influence of strict sperm morphology on the results of classic in vitro fertilization
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OBJECTIVE: To determine the influence of the concentration of oval spermatozoa according to the strict morphology criterion in men with normal sperm concentration following the World Health Organization criteria on the results of classic IVF. MATERIALS AND METHODS: Based on review of patient charts, this study included infertile couples presenting with female causes for infertility or unexplained infertility, in whom men presented with normal spermogram values for sperm concentration, sperm motility, volume of ejaculate and total sperm count after semen processing greater than 20 million. Based on the value obtained in strict sperm morphology, patients were divided into three groups: in Group A, patients with values between 0 % and 4 %; in group B, between 5 % and 14 %, and in group C, patients with sperm morphology greater than 14 %. The outcomes analyzed were oocyte fertilization rate, biochemical pregnancy rate, clinical pregnancy rate and rate of liveborns. RESULTS: A total of 244 cases met the inclusion criteria, 27 of them in group A, 165 in group B, and 52 in group C. The mean fertilization rate and the rate of liveborns were, respectively: 71.9 % and 33.3 % in group A; 80.9 % and 24.2 % in group B, and 78.8 % and 28.8 % in group C. There was no statistical difference among the groups in any of the outcomes analyzed. CONCLUSION: The values of strict sperm morphology, as proposed by Kruger and adopted by the World Health Organization, had no infl uence on the results of classic in vitro fertilization in the studied sample.
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Semen parameters have traditionally been used as an indicator for oocyte fertilization and attainment of pregnancy.
“Among the many factors that influence the outcomes of IVF, semen parameters have traditionally been used as an indicator for oocyte fertilization and attainment of pregnancy in addition to the quality of the oocyte.20”
From Men with a complete absence of normal sperm morphology exhibit high rates of success without assisted reproduction (2017) · cites this paper as [20]
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Research works printed but not linked: 22
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Smith, R., Kovac, J., Cajipe, M., Lamb, D., & Lipshultz, L. (2017) · Asian Journal of Andrology · doi:10.4103/1008-682x.189211 · Cited by 66 · see citing works
- Authors
- Ghirelli-Filho, M., Mizrahi, F. E., Pompeo, A. C. L., & Glina, S.
- Affiliations
- Sao Paulo and Faculdade de Medicina do ABC, Brazil
- Faculdade de Medicina do ABC (BR)
- ORCID
- Glina, Sidney
- Venue
- International braz j urol
- Publisher
- FapUNIFESP (SciELO)
- Published
- 2012-08
- Volume
- 38
- Issue
- 4
- Pages
- 519-528
- ISSN
- 1677-5538 (ISSN-L)
- OpenAlex
- W2141106070
- Cited by
- 14
- References
- 0
- Citations by year
- 2020: 2 · 2019: 1 · 2018: 2 · 2017: 3 · 2016: 3 · 2015: 1 · 2014: 2
- FWCI
- 1.12
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by-nc
- Locations
- International braz j urol (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
- Americanae (AECID Library) (submittedVersion, cc-by-nc)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
- Keywords
- sperm morphology, IVF outcomes, oocyte fertilization rate, biochemical pregnancy, clinical pregnancy rate, live birth rate, male infertility, unexplained infertility
- MeSH terms
- Adult, Age Factors, Female, Fertilization in Vitro, Humans, Male, Pregnancy, Reference Values, Sperm Count, Spermatozoa, World Health Organization, Chi-Square Distribution, Pregnancy Rate
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