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Neutrophil Infiltration and Chemokines
Abstract
Neutrophil infiltration is mainly mediated by ELR+ CXC chemokines and is regulated through interactions between various stimulants and cells, which are perhaps more complex than previously thought. In this review, I describe the current view of the roles of neutrophil-selective chemokines such as IL-8, MIP-2, and KC by choosing several in vivo models. I also illustrate how these three chemokines are induced and how they are involved in neutrophil infiltration. Finally, I introduce synthetic compounds with high efficacy in the prevention of ischemia reperfusion injury.
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Citations
Cited by
Tumor-associated neutrophils: friend or foe?
Fridlender, Z. G., & Albelda, S. M. (2012) · Carcinogenesis · doi:10.1093/carcin/bgs123 · Cited by 699
An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action
Gibbs, J., Ince, L., Matthews, L., Mei, J., Bell, T., Yang, N., Saer, B., Begley, N., Poolman, T., Pariollaud, M., et al. (2014) · Nature Medicine · doi:10.1038/nm.3599 · Cited by 455
Sun, D., Novotny, M., Bulek, K., Liu, C., Li, X., & Hamilton, T. (2011) · Nature Immunology · doi:10.1038/ni.2081 · Cited by 232
Bachman, M. A., Miller, V. L., & Weiser, J. N. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000622 · Cited by 186
Metadata
- Authors
- Kobayashi, Y.
- Venue
- Critical Reviews™ in Immunology
- Publisher
- Begell House
- Published
- 2006
- Volume
- 26
- Issue
- 4
- Pages
- 307-316
- ISSN
- 0197-3355 (ISSN-L)
- 2162-6472
- OpenAlex
- W2016667273
- Cited by
- 176
- References
- 0
- FWCI
- 7.75
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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