The DOI matches its Crossref record; 105 of the 105 references it cites were found in a registry or an index.
Animal Models for Medical Countermeasures to Radiation Exposure
Open accessAbstract
Since September 11, 2001, there has been the recognition of a plausible threat from acts of terrorism, including radiological or nuclear attacks. A network of Centers for Medical Countermeasures against Radiation (CMCRs) has been established across the U.S.; one of the missions of this network is to identify and develop mitigating agents that can be used to treat the civilian population after a radiological event. The development of such agents requires comparison of data from many sources and accumulation of information consistent with the "Animal Rule" from the Food and Drug Administration (FDA). Given the necessity for a consensus on appropriate animal model use across the network to allow for comparative studies to be performed across institutions, and to identify pivotal studies and facilitate FDA approval, in early 2008, investigators from each of the CMCRs organized and met for an Animal Models Workshop. Working groups deliberated and discussed the wide range of animal models available for assessing agent efficacy in a number of relevant tissues and organs, including the immune and hematopoietic systems, gastrointestinal tract, lung, kidney and skin. Discussions covered the most appropriate species and strains available as well as other factors that may affect differential findings between groups and institutions. This report provides the workshop findings.
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Cited by
Riehl, T. E., Alvarado, D., Ee, X., Zuckerman, A., Foster, L., Kapoor, V., Thotala, D., Ciorba, M. A., & Stenson, W. F. (2019) · Gut · doi:10.1136/gutjnl-2018-316226 · Cited by 228
Jalili-Firoozinezhad, S., Prantil-Baun, R., Jiang, A., Potla, R., Mammoto, T., Weaver, J. C., Ferrante, T. C., Kim, H. J., Cabral, J. M. S., Levy, O., et al. (2018) · Cell Death & Disease · doi:10.1038/s41419-018-0304-8 · Cited by 209
Limitations in predicting the space radiation health risk for exploration astronauts
Chancellor, J. C., Blue, R. S., Cengel, K. A., Auñón-Chancellor, S. M., Rubins, K. H., Katzgraber, H. G., & Kennedy, A. R. (2018) · npj Microgravity · doi:10.1038/s41526-018-0043-2 · Cited by 183
Animal models for acute radiation syndrome drug discovery
Singh, V. K., Newman, V. L., Berg, A. N., & MacVittie, T. J. (2015) · Expert Opinion on Drug Discovery · doi:10.1517/17460441.2015.1023290 · Cited by 139
Self-citationSingh, V. K., & Seed, T. M. (2021) · International Journal of Radiation Biology · doi:10.1080/09553002.2021.1969054 · Cited by 88
Metadata
- Authors
- Williams, J. P., Brown, S. L., Georges, G. E., Hauer-Jensen, M., Hill, R. P., Huser, A. K., Kirsch, D. G., MacVittie, T. J., Mason, K. A., Medhora, M. M., Moulder, J. E., Okunieff, P., Otterson, M. F., Robbins, M. E., Smathers, J. B., & McBride, W. H.
- Venue
- Radiation Research
- Publisher
- Radiation Research Society
- Published
- 2010-04
- Volume
- 173
- Issue
- 4
- Pages
- 557-578
- ISSN
- 0033-7587 (ISSN-L)
- 1938-5404
- OpenAlex
- W2130927464
- Cited by
- 423
- References
- 105
- FWCI
- 16.15
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Williams, J. P., Brown, S. L., Georges, G. E., Hauer-Jensen, M., Hill, R. P., Huser, A. K., Kirsch, D. G., MacVittie, T. J., Mason, K. A., Medhora, M. M., Moulder, J. E., Okunieff, P., Otterson, M. F., Robbins, M. E., Smathers, J. B., & McBride, W. H. (2010). Animal Models for Medical Countermeasures to Radiation Exposure. Radiation Research. https://doi.org/10.1667/rr1880.1
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
