Integrative molecular bioinformatics study of human adrenocortical tumors: microRNA, tissue-specific target prediction, and pathway analysis

Tömböl, Zsófia, Szabó, Peter M, Molnár, Viktor, Wiener, Zoltán, Tölgyesi, Gergely, Horányi, János, Riesz, Peter, Reismann, Peter, Patócs, Attila, Likó, István, Gaillard, Rolf-Christian, Falus, András, Rácz, Károly, Igaz, Peter·2009·Endocrine Related Cancer
DOI 10.1677/erc-09-0096

Cited by (175)

Items 101–175 of 175

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  2. Analysis of Circulating MicroRNAs In Vivo following Administration of Dexamethasone and Adrenocorticotropin
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  4. miR-375 negatively regulates the synthesis and secretion of catecholamines by targeting Sp1 in rat adrenal medulla
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  5. MECHANISMS OF ENDOCRINOLOGY: Cell cycle regulation in adrenocortical carcinoma
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  6. CCNB2 and AURKA overexpression may cause atypical mitosis in Japanese cortisol-producing adrenocortical carcinoma with TP53 somatic variant
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  7. C-MYC modulation induces responsiveness to paclitaxel in adrenocortical cancer cell lines
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  8. Pediatric adrenocortical tumors: diagnosis, management and advancements in the understanding of the genetic basis and therapeutic implications
    Sonir Roberto Rauber Antonini, Letícia Ferro Leal, Marcelo M Cavalcanti · 2014 · Expert Review of Endocrinology & Metabolism
  9. Vitamin D receptor hypermethylation as a biomarker for pediatric adrenocortical tumors
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  10. Molecular markers and targeted therapies for adrenocortical carcinoma
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  11. Essential Role of the 14q32 Encoded miRNAs in Endocrine Tumors
    Lilla Krokker, Attila Patócs, Henriett Butz · 2021 · Genes
  12. Amplification of theInsulin-Like Growth Factor 1 ReceptorGene Is a Rare Event in Adrenocortical Adenocarcinomas: Searching for Potential Mechanisms of Overexpression
    T.C. Ribeiro, Alexander A.L. Jorge, Madson Queiroz Almeida, Beatriz M. P. Mariani, Mirian Yumie Nishi, Berenice Bilharinho Mendonca, Maria Candida Barisson Villares Fragoso, Ana Cláudia Latronico · 2014 · BioMed Research International
  13. MicroRNAs and Adrenocortical Tumors: Where do we Stand on Primary Aldosteronism?
    Zsófia Tömböl, Péter István Turai, Ábel Decmann, Péter Igaz · 2020 · Hormone and Metabolic Research
  14. Introduction to microRNAs: Biogenesis, Action, Relevance of Tissue microRNAs in Disease Pathogenesis, Diagnosis and Therapy—The Concept of Circulating microRNAs
    Zsolt Nagy, Péter Igaz · 2015 · Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions
  15. 5th International ACC Symposium: Classification of Adrenocortical Cancers from Pathology to Integrated Genomics: Real Advances or Lost in Translation?
    Ronald R. de Krijger, Jerome Yves Bertherat · 2015 · Hormones and Cancer
  16. Szlaki molekularne w raku kory nadnercza — od wiedzy o sygnalizacji komórkowej do metod diagnostyki i leczenia
    Paulina Szyszka, Ashley Barry Grossman, Salvador J. Díaz‐Cano, Dorota Dworakowska B · 2015 · Endokrynologia Polska
  17. Identification of Dysregulated Expression of G Protein Coupled Receptors in Endocrine Tumors by Bioinformatics Analysis: Potential Drug Targets?
    Valentine Suteau, Mathilde Munier, Rym Ben Boubaker, Méline Wery, Daniel Henrion, Patrice Rodien, Claire Briet · 2022 · Cells
  18. Suggested roles for microRNA in tumors
    Pál Perge, Zsolt Nagy, Iván Igaz, Péter Igaz · 2015 · BioMolecular Concepts
  19. MicroRNAs and Long Non-Coding RNAs in Adrenocortical Carcinoma
    Mario Detomas, Claudia Pivonello, Bianca Pellegrini, Laura‐Sophie Landwehr, Silviu Sbiera, Rosario Pivonello, Cristina Lucia Ronchi, Annamaria Colao, Barbara Altieri, Maria Cristina De Martino · 2022 · Cells
  20. MiR-486-3p was downregulated at microRNA profiling of adrenals of multiple endocrine neoplasia type 1 mice, and inhibited human adrenocortical carcinoma cell lines
    Su‐Chen Li, Azita Monazzam, Masoud Razmara, Xia Chu, Peter L. H. Stalberg, Britt M. Skogseid · 2021 · Scientific Reports
  21. Wnt-Signaling Regulated by Glucocorticoid-Induced miRNAs
    Henriett Butz, Katalin Viola Mészáros, István Likó, Attila Patócs · 2021 · International Journal of Molecular Sciences
  22. MicroRNA expression profile predicts prognosis of pediatric adrenocortical tumors
    Luciana Chain Veronez, Paola Fernanda Fedatto, Carolina Alves Pereira Corrêa, Régia Caroline Peixoto Lira, Mirella Baroni, Keteryne Rodrigues da Silva, Paula Santos, David Santos Marco Antônio, Rosane Gomes de Paula Queiróz, Sonir Roberto Rauber Antonini et al. · 2021 · Pediatric Blood & Cancer
  23. Vitamin D receptor activation is a feasible therapeutic target to impair adrenocortical tumorigenesis
    Ana Carolina Bueno, Candy Bellido More, Junier Marrero-Gutiérrez, Danillo C. Almeida-e-Silva, Letícia Ferro Leal, Ana Paula Montaldi, Fernando Silva Ramalho, Ricardo Z. N. Vêncio, Margaret de Castro, Sonir Roberto Rauber Antonini · 2022 · Molecular and Cellular Endocrinology
  24. Why is microRNA action tissue specific? A putative defense mechanism against growth disorders, tumor development or progression mediated by circulating microRNA?
    Iván Igaz, Péter Igaz · 2015 · Medical Hypotheses
  25. MicroRNA Era: The Importance for Diagnosis and Prognosis of Adrenocortical Tumors
    João Evangelista Bezerra Neto, Ana Cláudia Latronico · 2014 · BioMed Research International
  26. The Diagnostic, Prognostic and Therapeutic Role of miRNAs in Adrenocortical Carcinoma: A Systematic Review
    Chrysoula Mytareli, Danae Anastasia Delivanis, Fani Athanasouli, Vassiliki Kalotychou, Marina Mantzourani, Eva N. Kassi, Anna G. Angelousi · 2021 · Biomedicines
  27. Pathogenesis of adrenocortical cancer
    Diána Rita Szabó, Adrienn Zsippai, Melinda R Bendes, Zsófia Tömböl, Péter Márton Szabó, Kàroly Rácz, Péter Igaz · 2010 · Orvosi Hetilap
  28. Adrenocortical Growth and Cancer
    Lucile Lefèvre, Jerome Yves Bertherat, Bruno Ragazzon · 2014 · Comprehensive physiology
  29. Circulating microRNAs in adrenal tumors
    Péter Igaz · 2019 · Current Opinion in Endocrinology Diabetes and Obesity
  30. Identification of Seven Aberrantly Methylated and Expressed Genes in Adrenocortical Carcinoma
    He Xiao, Weixiang He, Ping Chen, Deqiang Xu, Guang Zeng, Zhuo Ya Li, Mingliu Huang, Xinghuan Wang, Michael E. DiSanto, Xinhua Zhang · 2019 · Frontiers in Endocrinology
  31. Molecular landscape and biomarker discovery in adrenocortical carcinoma: An integrative review of bioinformatics and translational insights
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  32. MicroRNAs in Genitourinary Malignancies: An Exciting Frontier of Cancer Diagnostics and Therapeutics
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  33. Therapeutic potential of targeting the FLNA‐regulated Wee1 kinase in adrenocortical carcinomas
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  34. Current and evolving treatment options in adrenocortical carcinoma: where do we stand and where do we want to go?
    Cristina Lucia Ronchi, Matthias Kroiß, Silviu Sbiera, Timo Deutschbein, Martin Faßnacht · 2014
  35. Proteome analysis of adrenal cortical tumors
    Hye Min Kim, Yu Kyung Lee, Ja Seung Koo · 2016 · Expert Review of Proteomics
  36. Tumores adrenocorticais na criança: da abordagem clínica à avaliação molecular
    Sonir Roberto Rauber Antonini, Leandro Machado Colli, Leticia Ferro, Lívia M. Mermejo, Margaret de Castro · 2011 · Arquivos Brasileiros de Endocrinologia & Metabologia
  37. MEN1 and microRNAs: The link between sporadic pituitary, parathyroid and adrenocortical tumors?
    Zsolt Nagy, Péter Szabó, Vince Kornél Grolmusz, Pál Perge, Iván Igaz, Attila Patócs, Péter Igaz · 2016 · Medical Hypotheses
  38. Differences in MicroRNA Expression Profiles of Adrenocortical Tumors – Letter
    Zsófia Tömböl, Péter Márton Szabó, Attila Patócs, Kàroly Rácz, Péter Igaz · 2010 · Clinical Cancer Research
  39. Bioinformatics Analysis and Experimental Identification of Immune-Related Genes and Immune Cells in the Progression of Retinoblastoma
    Shuilian Chen, Xi Chen, Ping Zhang, Shuxia Chen, Xiao Wang, Qian Luo, Zedu Cui, Yuke Huang, Linxi Wan, Xiangtao Hou et al. · 2022 · Investigative Ophthalmology & Visual Science
  40. Effect of retinoic acid on human adrenal corticosteroid synthesis
    Antonella Sesta, Maria Francesca Cassarino, Laura Tapella, Luigi Castelli, Francesco Cavagnini, Francesca Pecori Giraldi · 2016 · Life Sciences
  41. Toward a pathway-centered approach for the treatment of adrenocortical carcinoma
    Kimberly J. Bussey, Michael J. Demeure · 2010 · Current Opinion in Oncology
  42. MicroRNA-149-3p expression correlates with outcomes of adrenocortical tumor patients and affects proliferation and cell cycle progression of H295A adrenocortical cancer cell line
    Keteryne Rodrigues da Silva, Luciana Chain Veronez, Carolina Alves Pereira Corrêa, Régia Caroline Peixoto Lira, Mirella Baroni, Rosane Gomes de Paula Queiróz, Sonir Roberto Rauber Antonini, José Andrés Yunes, Sílvia Regina Brandalise, Luíz Gonzaga Tone et al. · 2022 · Human Cell
  43. A mikro-RNS-ek patogenetikai és diagnosztikai szerepe mellékvesekéreg-carcinomában
    Zsolt Nagy, Ábel Decmann, Pál Perge, Péter Igaz · 2018 · Orvosi Hetilap
  44. Updates on WHO 5th edition classification, molecular characteristics and tumor microenvironment of adrenocortical carcinomas
    Yuto Yamazaki, Yuta Tezuka, Yoshikiyo Ono, Fumitoshi Satoh, Hironobu Sasano, Takashi Suzuki · 2024 · Endocrine Journal
  45. Gene Expression and Regulation in Adrenocortical Tumorigenesis
    Annabelle L. Fonseca, James Michael Healy, John W. Kunstman, Reju M. Korah, Tobias Carling · 2012 · Biology
  46. Analysis of Differentially Expressed Genes That Aggravate Metabolic Diseases in Depression
    Sukanta Bhadra, Siyu Chen, Chang Liu · 2021 · Life
  47. The role of microRNAs in the adrenocortical carcinomas
    Yu Xin, Zheng Li · 2015 · Tumor Biology
  48. MicroRNAs in Aldosterone Production and Action
    Scott Mackay MacKenzie, Josie C. van Kralingen, Hannah Martin, Eleanor Davies · 2019 · IntechOpen eBooks
  49. In silico analysis of pathways affected by differentially expressed microRNA in adrenocortical tumors.
    Adrienn Zsippai, Péter Márton Szabó, Dorottya Szabó, Zsolt Nagy, Attila Patócs, Kàroly Rácz, Péter Igaz · 2013 · PubMed
  50. Significance of microRNA expression in body fluids in the diagnosis of gastrointestinal tumors
    Iván Igaz, Lajos Topa · 2013 · Orvosi Hetilap
  51. Long noncoding RNA PAGBC contributes to nitric oxide (NO) production by sponging miR‐511 in airway hyperresponsiveness upon intubation
    Lingxia Li, Yuan‐Jun Li, Jia‐Xuan He · 2018 · Journal of Cellular Biochemistry
  52. Exploratory Circular RNA Profiling in Adrenocortical Tumors
    Péter István Turai, Gábor Nyírő, Katalin Borka, Tamás Micsík, István Likó, Attila Patócs, Péter Igaz · 2022 · Cancers
  53. Comprehensive Multiomics Analysis Reveals Potential Diagnostic and Prognostic Biomarkers in Adrenal Cortical Carcinoma
    Xiunan Li, Jiayi Li, Leizuo Zhao, Zicheng Wang, Peizhi Zhang, Yingkun Xu, Guangzhen Wu · 2022 · Computational and Mathematical Methods in Medicine
  54. Can microRNA be used as a Biomarker in Adrenocortical Cancer?
    Péter Igaz · 2015 · International Journal of Endocrine Oncology
  55. Clinical and functional aspects of microRNA regulation in human cancers
    Stefano Caramuta · 2012 · Figshare
  56. Papel do LIN28, uma proteína ligadora de RNAs, na tumorigênese adrenocortical
    André Murad Faria · 2014
  57. Análise da expressão e do silenciamento do receptor tipo 1 do fator de crescimento semelhante à insulina em tumores adrenocorticais humanos
    T.C. Ribeiro · 2015 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  58. Análise do perfil de expressão de microRNAs em tumores adrenocorticais benignos e malignos humanos
    João Evangelista Bezerra Neto · 2014
  59. Could miRNA Replacement be a Novel Therapy for Adrenocortical Carcinoma?
    Anthony Robert Glover, Nunki Hassan, Lauren Jin Suk Joo, G. Kwok, Jing Zhao, Stan B. Sidhu · 2016 · International Journal of Endocrine Oncology
  60. Análise dos genes DICER1 e TARBP2 em tumores do córtex da suprarrenal de crianças e adultos
    Gabriela Resende Vieira de Sousa · 2015
  61. Genome-Wide Studies in Adrenocortical Neoplasia
    Thomas J. Giordano · 2009 · Springer eBooks
  62. Genetics of Adrenocortical Cancers
    Guillaume Assié, Jerome Yves Bertherat · 2016 · Springer eBooks
  63. Caratterizzazione genomica del carcinoma surrenalico
    Letizia Canu, Roberta Armignacco, Giada Poli, Giulia Cantini, Tonino Ercolino, Massimo Mannelli, Michaela Luconi · 2016 · L Endocrinologo
  64. Update on microRNA as Biomarkers of Adrenocortical Cancer: Perspective on Circulating microRNA
    Péter Igaz · 2017 · International Journal of Endocrine Oncology
  65. Role of MIR-29B-1 and MIR-29A in endocrine-resistant breast cancer.
    Penn Muluhngwi · 2017
  66. A expressão dos marcadores de células-tronco, SF1 e DAX1 no desenvolvimento do córtex adrenal humano e sua associação com a via Wnt/beta-catenina na tumorigênese adrenocortical
    Marcelo M Cavalcanti · 2018 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  67. Non-Coding RNAS and Steroidogenesis
    Kenji Ohe · 2018 · Biomedical Journal of Scientific & Technical Research
  68. Adrenocortical Carcinoma
    Bruno Allolio, Martin Faßnacht · 2015 · Elsevier eBooks
  69. Análise do perfil de expressão do miR-483-3p e do miR-630 em tumores adrenocorticais e o efeito dessa modulação na tumorigênese da adrenal
    Carolina Alves Pereira Corrêa · 2020
  70. Avaliação dos miR-214-3p, miR-150-5p, miR-142-5p, miR-708-5p, miR-34a-5p e miR-139-3p em tumores adrenocorticais da infância: correlação com achados clínicos e biológicos
    Cecília Fernandes Lorea · 2021
  71. Multi-Omics Analysis Reveals the Mechanism of Exosome-Related Genes in Adrenocortical Carcinogenesis
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  72. Adrenocortical carcinoma: Genetics and molecular markers
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  73. Progression tumorale dans un modèle murin de carcinogénèse surrénalienne ciblée induite par antigène T de SV 40 : Recherche de cibles thérapeutiques pour le corticosurrénalome.
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