The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Association of Bone Activity, Calcium Load, Aortic Stiffness, and Calcifications in ESRD
Open accessAbstract
An inverse relationship between arterial calcifications and bone activity has been documented in patients with ESRD. Calcium overload is associated with arterial calcification, which is associated with arterial stiffening. Whether bone activity interacts with calcium load, aortic stiffness, or arterial calcification is unknown. This study assessed the impact of bone activity on the relationships between the dosage of calcium-containing phosphate binders and aortic stiffness (measured by pulse wave velocity) or abdominal aorta calcification score. Aortic stiffness and calcification were both positively associated with calcium load and negatively associated with bone activity. A significant interaction was found between dosage of calcium-containing phosphate binders and bone activity such that calcium load had a significantly greater influence on aortic calcifications and stiffening in the presence of adynamic bone disease. Independent of any other factor, including dosage of calcium-containing phosphate binders, adynamic bone was associated with greater aortic stiffening, suggesting cross-talk between the bone and arterial walls.
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Cites
Endocrine regulation of energy metabolism by the skeleton
Lee, N. K., Sowa, H., Hinoi, E., Ferron, M., Ahn, J. D., Confavreux, C., Dacquin, R., Mee, P. J., McKee, M. D., Jung, D. Y., et al. (2007) · Cell · doi:10.1016/j.cell.2007.05.047 · Cited by 2,554
Cited by
Vascular Smooth Muscle Cells and Arterial Stiffening: Relevance in Development, Aging, and Disease
Lacolley, P., Regnault, V., Segers, P., & Laurent, S. (2017) · Physiological Reviews · doi:10.1152/physrev.00003.2017 · Cited by 734
Metadata
- Authors
- London, G. A. A. M., Marchais, S. J., Gue[Combining Acute Accent]rin, A. P., Boutouyrie, P., Me[Combining Acute Accent]tivier, F., & de Vernejoul, M.-C.
- Venue
- Journal of the American Society of Nephrology
- Published
- 2008-09
- Volume
- 19
- Issue
- 9
- Pages
- 1827-1835
- ISSN
- 1046-6673 (ISSN-L)
- OpenAlex
- W2151434420
- Cited by
- 296
- References
- 1
- FWCI
- 20.88
- Type
- journal article
- Language
- en
- Open access
- green
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- London, G. A. A. M., Marchais, S. J., Gue[Combining Acute Accent]rin, A. P., Boutouyrie, P., Me[Combining Acute Accent]tivier, F., & de Vernejoul, M.-C. (2008). Association of Bone Activity, Calcium Load, Aortic Stiffness, and Calcifications in ESRD. Journal of the American Society of Nephrology. https://doi.org/10.1681/asn.2007050622
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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