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Cited by 420

The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.

Exercise in Patients on Dialysis: A Multicenter, Randomized Clinical Trial

Open access
Manfredini, Fabio, Mallamaci, Francesca, D’Arrigo, Graziella, Baggetta, Rossella, Bolignano, Davide, Torino, Claudia, Lamberti, Nicola, Bertoli, Silvio, Ciurlino, Daniele, Rocca-Rey, Lisa, Barillà, Antonio, Battaglia, Yuri, Rapanà, Renato Mario, Zuccalà, Alessandro, Bonanno, Graziella, Fatuzzo, Pasquale, Rapisarda, Francesco, Rastelli, Stefania, Fabrizi, Fabrizio, Messa, Piergiorgio, De Paola, Luciano, Lombardi, Luigi, Cupisti, Adamasco, Fuiano, Giorgio, Lucisano, Gaetano, Summaria, Chiara, Felisatti, Michele, Pozzato, Enrico, Malagoni, Anna Maria, Castellino, Pietro, Aucella, Filippo, Abd ElHafeez, Samar, Provenzano, Pasquale Fabio, Tripepi, Giovanni, Catizone, Luigi, Zoccali, Carmine·2017·Journal of the American Society of Nephrology
DOI 10.1681/asn.2016030378
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Abstract

Previous studies have suggested the benefits of physical exercise for patients on dialysis. We conducted the Exercise Introduction to Enhance Performance in Dialysis trial, a 6-month randomized, multicenter trial to test whether a simple, personalized walking exercise program at home, managed by dialysis staff, improves functional status in adult patients on dialysis. The main study outcomes included change in physical performance at 6 months, assessed by the 6-minute walking test and the five times sit-to-stand test, and in quality of life, assessed by the Kidney Disease Quality of Life Short Form (KDQOL-SF) questionnaire. We randomized 296 patients to normal physical activity (control; n=145) or walking exercise (n=151); 227 patients (exercise n=104; control n=123) repeated the 6-month evaluations. The distance covered during the 6-minute walking test improved in the exercise group (mean distance±SD: baseline, 328±96 m; 6 months, 367±113 m) but not in the control group (baseline, 321±107 m; 6 months, 324±116 m; P<0.001 between groups). Similarly, the five times sit-to-stand test time improved in the exercise group (mean time±SD: baseline, 20.5±6.0 seconds; 6 months, 18.2±5.7 seconds) but not in the control group (baseline, 20.9±5.8 seconds; 6 months, 20.2±6.4 seconds; P=0.001 between groups). The cognitive function score (P=0.04) and quality of social interaction score (P=0.01) in the kidney disease component of the KDQOL-SF improved significantly in the exercise arm compared with the control arm. Hence, a simple, personalized, home-based, low-intensity exercise program managed by dialysis staff may improve physical performance and quality of life in patients on dialysis.

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Metadata

Authors
Manfredini, F., Mallamaci, F., D’Arrigo, G., Baggetta, R., Bolignano, D., Torino, C., Lamberti, N., Bertoli, S., Ciurlino, D., Rocca-Rey, L., Barillà, A., Battaglia, Y., Rapanà, R. M., Zuccalà, A., Bonanno, G., Fatuzzo, P., Rapisarda, F., Rastelli, S., Fabrizi, F., Messa, P., De Paola, L., Lombardi, L., Cupisti, A., Fuiano, G., Lucisano, G., Summaria, C., Felisatti, M., Pozzato, E., Malagoni, A. M., Castellino, P., Aucella, F., Abd ElHafeez, S., Provenzano, P. F., Tripepi, G., Catizone, L., & Zoccali, C.
Venue
Journal of the American Society of Nephrology
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2016-12-01
Volume
28
Issue
4
Pages
1259-1268
ISSN
  • 1046-6673 (ISSN-L)
  • 1533-3450
DOI
10.1681/asn.2016030378
OpenAlex
W2559119607
Cited by
420
References
33
FWCI
21.93
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Exercise in Patients on Dialysis: A Multicenter, Randomized Clinical Trial. https://app.cochat.ai/papers/10.1681/asn.2016030378
The paper
Manfredini, F., Mallamaci, F., D’Arrigo, G., Baggetta, R., Bolignano, D., Torino, C., Lamberti, N., Bertoli, S., Ciurlino, D., Rocca-Rey, L., Barillà, A., Battaglia, Y., Rapanà, R. M., Zuccalà, A., Bonanno, G., Fatuzzo, P., Rapisarda, F., Rastelli, S., Fabrizi, F., . . . Zoccali, C. (2017). Exercise in Patients on Dialysis: A Multicenter, Randomized Clinical Trial. Journal of the American Society of Nephrology. https://doi.org/10.1681/asn.2016030378

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.