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Component-Based Allergen-Microarray: Der p 2 and Der f 2 Dust Mite Sensitization Is More Common in Patients With Severe Asthma
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In the citing paper
“One factor strongly associated with severe asthma in children and adolescents is allergic sensitization (82–87).”
From Epidemiology of Asthma in Children and Adults (2019) · cites this paper as [87]
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Epidemiology of Asthma in Children and Adults
Dharmage, S. C., Perret, J. L., & Custovic, A. (2019) · Frontiers in Pediatrics · doi:10.3389/fped.2019.00246 · Cited by 1,200
EAACI Guidelines on Allergen Immunotherapy: House dust mite‐driven allergic asthma
Agache, I. O., Lau, S., Akdiş, C. A., Smolińska, S., Bonini, M., Cavkaytar, Ö., Flood, B., Gajdanowicz, P., Izuhara, K., Kalaycı, Ö., et al. (2019) · Allergy · doi:10.1111/all.13749 · Cited by 325
“Substantial evidence associates allergic conditions such as asthma, allergic rhinitis (AR), atopic dermatitis (AD) with exposure to HDM, or other indoor allergens.(23-30) Data from longitudinal investigations suggest that the development of sensitization to HDM occurs before polysensitization.”
BackgroundA WAO—ARIA—GA2LEN Consensus Document on Molecular-Based Allergy Diagnosis (PAMD@): Update 2020
Ansotegui, I. J., Melioli, G., Canonica, G. W., Gómez, R. M., Jensen-Jarolim, E., Ebisawa, M., Luengo, O., Caraballo, L., Passalacqua, G., Poulsen, L. K., et al. (2020) · World Allergy Organization Journal · doi:10.1016/j.waojou.2019.100091 · Cited by 122
“Others have reported the specific impact of Der p 2 and Der f 2 allergens on severe asthma.(126) Cysteine proteases, such as Der p 1 and papain, may have a percutaneous sensitization capacity, in addition to the described capacity to disrupt bronchial epithelial barriers.”
BackgroundDel Giacco, S. R., Bakirtas, A., Bel, E., Custovic, A., Diamant, Z., Hamelmann, E., Heffler, E., Kalayci, Ö., Saglani, S., Sergejeva, S., et al. (2017) · Allergy · doi:10.1111/all.13072 · Cited by 130
“Sensitization to mite allergens Der p 2 and Der f 2 has been reported to be more common in severe asthma (39).”
BackgroundJiménez‐Feijoo, R., Pascal, M., Moya, R., Riggioni, C., Domínguez, O., Lózano, J., Álvaro-Lozano, M., Piquert, M., Machinena, A., Folqué, M. D. M., et al. (2019) · Journal of Investigational Allergology and Clinical Immunology · doi:10.18176/jiaci.0431 · Cited by 56
Component-Resolved Diagnosis in Allergic Rhinitis and Asthma
Eiringhaus, K., Renz, H. E., Matricardi, P. M., & Skevaki, C. L. (2018) · The Journal of Applied Laboratory Medicine · doi:10.1373/jalm.2018.026526 · Cited by 37
Der f 35: An MD ‐2‐like house dust mite allergen that cross‐reacts with Der f 2 and Pso o 2
Fujimura, T., Aki, T., Isobe, T., et al. (2017) · Allergy · doi:10.1111/all.13192 · Cited by 26
“In another report, high rates of sensitivity to group 2 HDM allergens were observed in patients with severe asthma; and patients with severe persistent asthma were more highly sensitized to HDM allergens, especially to those of group 2.(19) Taken together, these results indicate that group 2 HDM allergens are clinical…”
BackgroundA Case of Hypocomplementemic Urticarial Vasculitis Syndrome Successfully Treated With Omalizumab
Nucera, E., Basta, F., Buonomo, A., et al. (2017) · Journal of Investigational Allergology and Clinical Immunology · doi:10.18176/jiaci.0191 · Cited by 16
Dual inhibition of airway inflammation and fibrosis by common β cytokine receptor blockade
Wang, H., Yip, K. H., Keam, S. P., Vlahos, R., Nichol, K., Wark, P. A. B., Toubia, J., Kral, A., Cildir, G., Pant, H., et al. (2023) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2023.10.021 · Cited by 17
González‐Pérez, R., Guedes, P. P., Pineda, F., Forstenlechner, P., Castillo, M., Mederos‐Luis, E., Aumayr, M., Matheu, V. M., Álava‐Cruz, C., & Sánchez‐Machín, I. (2020) · International Archives of Allergy and Immunology · doi:10.1159/000510118 · Cited by 15
Larco-Rojas, X., González‐Gutiérrez, M. L., Vázquez‐Cortés, S., et al. (2017) · Journal of Investigational Allergology and Clinical Immunology · doi:10.18176/jiaci.0195 · Cited by 13
Caraballo, L. R. (2017) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2017.1292132 · Cited by 13
“addition to Der p 1 and Der p 2 [24], but also could show that not”
BackgroundComponent‐specific clusters for diagnosis and prediction of allergic airway diseases
Howard, R., Fontanella, S., Simpson, A., Murray, C. S., Čustović, A., & Rattray, M. (2024) · Clinical & Experimental Allergy · doi:10.1111/cea.14468 · Cited by 12
“The association we describe here between the ‘Group 2’ (Der p 2, Der f 2) pattern in HDM cluster and asthma was also seen in another cohort, 36 raising the question of whether properties Der FIGURE 3 Odds ratios and 95% CIs from univariable logistic regression for the associations between the…”
BackgroundErfurt-Berge, C. S., & Mahler, V. (2017) · Journal of Investigational Allergology and Clinical Immunology · doi:10.18176/jiaci.0188 · Cited by 11
Gellrich, D., Högerle, C., Becker, S., & Gröger, M. (2018) · Journal of Investigational Allergology and Clinical Immunology · doi:10.18176/jiaci.0299 · Cited by 11
“This result contrasts with those reported by Sylvestre et al [34], who had found higher titers of Der p 2 in patients with severe atopic asthma.”
de Souza, T. M. O., Fernandes, J. S., Santana, C. V. N., Lessa, M. M., & Cruz, Á. A. (2023) · Brazilian Journal of Otorhinolaryngology · doi:10.1016/j.bjorl.2023.101351 · Cited by 10
How In Vitro Assays Contribute to Allergy Diagnosis
Casset, A., Khayath, N., & Frederic de, B. L. A. Y. (2016) · Current Allergy and Asthma Reports · doi:10.1007/s11882-016-0659-9 · Cited by 8
Self-citationEremija, J., & Carr, T. F. (2022) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0042-1749454 · Cited by 8
Cluster analysis of indoor environmental factors associated with symptoms of mite allergy
Virot, E., Godet, J., Khayath, N., Ott, M., Dazy, A., & Frederic de, B. L. A. Y. (2019) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2019.05.020 · Cited by 7
Self-citationWang, W., An, G., Li, Y., et al. (2020) · Cellular Immunology · doi:10.1016/j.cellimm.2020.104038 · Cited by 6
Akashi, M., & Sato, S. (2017) · Journal of Investigational Allergology and Clinical Immunology · doi:10.18176/jiaci.0190 · Cited by 5
The Epidemiology of Severe Childhood Asthma
Čustović, A., & Martínez, F. D. (2019) · Springer eBooks · doi:10.1007/978-3-030-27431-3_1 · Cited by 2
Roxbury, C. R., & Lin, S. Y. (2020) · Current Otorhinolaryngology Reports · doi:10.1007/s40136-020-00268-9 · Cited by 1
Marcot, C., Migueres, N., Ott, M., Khayath, N., & Frederic de, B. L. A. Y. (2023) · Revue des Maladies Respiratoires · doi:10.1016/j.rmr.2023.06.001 · Cited by 3
Self-citationХоха, Р. Н., Парамонова, Н. С., & Zavodnik, L. B. (2022) · Allergology and Immunology in Pediatrics · doi:10.53529/2500-1175-2022-1-39-41 · Cited by 1
Marqueurs de sévérité et marqueurs prédictifs de réponse au traitement dans l’asthme sévère
Sésé, L., Mahay, G., Barnig, C., Guibert, N. M., Leroy, S., & Guilleminault, L. (2022) · Revue des Maladies Respiratoires · doi:10.1016/j.rmr.2022.08.009 · Cited by 1
Self-citationUkleja-Sokołowska, N., Lis, K., Bartuzi, M., et al. (2023) · Advances in Dermatology and Allergology · doi:10.5114/ada.2023.132071 · Cited by 1
“This relationship was particularly strongly expressed in the case of allergy to Der p 2 and Der f 2 [27].”
BackgroundSposato, B., Scalese, M., Milanese, M., et al. (2017) · Journal of Investigational Allergology and Clinical Immunology · doi:10.18176/jiaci.0196
Ceballos, M., Castro, C. D., Gabriel, M. F., et al. (2017) · Journal of Investigational Allergology and Clinical Immunology · doi:10.18176/jiaci.0198
Sensibilization to the allergens of domestic dust mites in children. Part 1
Zavodnik, L. B., Хоха, Р. Н., & Khokha, A. M. (2020) · Vestnik of Vitebsk State Medical University · doi:10.22263/2312-4156.2020.5.17
Sunki nealerginė astma: ar visada nealerginė?
Malinauskienė, L., Griguola, L., Černiauskas, K., & Chomičienė, A. (2021) · Pulmonology and allergology · doi:10.37499/pia.757
Specific immunoglobulin E profiles in sensitized Swedish and Spanish children with severe asthma
Martí‐Garrido, J., Konradsen, J. R., Hedlin, G., van Hage, M., Nieto, A., Nieto, M., Uixera, S., & Mazón, Á. (2023) · doi:10.37349/eaa.2023.00019
10.1016/b978-0-323-54427-6.00013-4
(2000) · Time to knit · doi:10.1016/b978-0-323-54427-6.00013-4
Urrego, J., Aglas, L., Huber, S., Belitardo, E. M. M. D. A., Briza, P., Cruz, Á. A., Salazar-Garcés, L. F., Cooper, P. J., Zakzuk, J. A., Caraballo, L. R., et al. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1815807
“These fi ndings were similar to previous studies associating Der p 2 sensitization with asthma and its severe phenotype (94, 95).”
Metadata
- Authors
- Sylvestre, L., Jégu, J., Metz-Favre, C., Barnig, C., Qi, S., & de Blay, F.
- Affiliations
- Hôpitaux Universitaires de Strasbourg (FR)
- Venue
- Journal of Investigational Allergology and Clinical Immunology
- Publisher
- Esmon Publicidad, SA
- Published
- 2016-04-01
- Volume
- 26
- Issue
- 2
- Pages
- 141-143
- ISSN
- 1018-9068 (ISSN-L)
- OpenAlex
- W2405022541
- Cited by
- 35
- References
- 0
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 5 · 2022: 4 · 2021: 1 · 2020: 6 · 2019: 5 · 2018: 2 · 2017: 8 · 2016: 2
- FWCI
- 5.34
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Investigational Allergology and Clinical Immunology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Immunology and Allergy › Allergic Rhinitis and Sensitization
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Keywords
- allergen microarray, Der p 2, Der f 2, house dust mite allergens, severe asthma, allergen sensitization, asthma phenotypes
- MeSH terms
- Adolescent, Adult, Aged, Allergens, Animals, Asthma, Female, Humans, Immunoglobulin E, Male, Middle Aged, Severity of Illness Index, Antigens, Dermatophagoides, Protein Array Analysis, Arthropod Proteins
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