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Protein C-mannosylation: facts and questions.

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Furmanek, A, Hofsteenge, J·2000·Acta Biochimica Polonica

Abstract

Among the posttranslational modifications of proteins, glycosylation is probably the most abundant one. Two main types of protein glycosylation have been known for several years, namely N-glycosylation and O-glycosylation. Their biochemical properties, structure and biosynthesis, have been described extensively. Their biological functions are also known for a number of proteins, although in many cases the function remains speculative despite continuous efforts. A few years ago, a new type of protein glycosylation was found, which is different from the above-mentioned ones. It was called C-glycosylation, since the sugar is linked to the protein through a carbon-carbon bond. This article reviews the biochemistry of C-glycosylation, the biosynthetic pathway and structural requirements. Possible biological functions of this modification are also discussed.

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Metadata

Authors
Furmanek, A., & Hofsteenge, J.
Venue
Acta Biochimica Polonica
Published
2000-09-30
Volume
47
Issue
3
Pages
781-789
ISSN
  • 0001-527X (ISSN-L)
  • 1734-154X
OpenAlex
W1978351897
Cited by
167
References
0
FWCI
0.68
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Protein C-mannosylation: facts and questions. https://app.cochat.ai/papers/10.18388/abp.2000_3996
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Furmanek, A., & Hofsteenge, J. (2000). Protein C-mannosylation: facts and questions. Acta Biochimica Polonica. https://doi.org/10.18388/abp.2000_3996

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