Disease-Related Stigma, Stigmatizers, Causes, and Consequences: A Systematic Review
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Background: Stigma is a sociological concept that is important in medicine and health because it threatens health as much as the disease itself. We aimed to explore the causes, stigmatizers, consequences and coping strategies related to the stigma of diseases by systematically analyzing relevant literature. Methods: This systematic review examined 65 articles on Disease-Related Stigma by searching Noormags, Magiran, SID, Google Scholar, and PubMed databases. The articles were published in Persian and English between 2001 and 2022 and conducted in Iran. We used a three-step systematic review process to select articles that met the research criteria. Results: Conflict in society, lack of knowledge, specific characteristics of the disease, and the contagious nature of disease are the main causes of stigma, leading to stigmatization by different groups such as significant others, generalized others, institutional others, and macro others. Patients experiencing stigma face various psychological, physical, and social complications, and they may use concealment as a coping strategy, which can pose a potential threat to society's general health. Conclusion: By knowing the causes and stigmatizers of disease-related, it is possible to reduce stigma with less cost and time.
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Internalized stigma is associated with feeling shame regarding one's stigmatized condition.
“Internalized stigma, where an individual identifies with a stigmatized group (such as a chronic illness population), is associated with feeling shame regarding one's stigmatized condition (Akbari, Mohammadi, and Hosseini 2023;Earnshaw et al. 2022;Luoma et al. 2008; The Public Health Agency of Sweden 2024).”
From Illness Stigma and Shame in People With Chronic Illnesses vs. SARS‐CoV‐2 Survivors: Associations With Psychological Distress Through Psychological Flexibility and Self‐Compassion. (2024) · cites this paper as Akbari, Mohammadi, and Hosseini 2023
The Results section, “Consequences of disease-related stigma,” identifies shame as a consequence of stigma and says these effects persist while patients perceive themselves as inferior. It does not specifically identify internalized stigma as the form associated with shame. (LLM, conf=0.82)
Experimental — accuracy not yet measuredShame is a part of internalized stigma.
“because shame is a part of internalized stigma (Akbari, Mohammadi, and Hosseini 2023)”
From Illness Stigma and Shame in People With Chronic Illnesses vs. SARS‐CoV‐2 Survivors: Associations With Psychological Distress Through Psychological Flexibility and Self‐Compassion. (2024) · cites this paper as Akbari, Mohammadi, and Hosseini 2023
The Results section, “Consequences of disease-related stigma” (page unavailable), identifies shame as a psychological consequence of stigma. It does not identify shame as a component of internalized stigma, which is the more specific relationship the citing sentence asserts. (LLM, conf=0.84)
Experimental — accuracy not yet measuredThe large direct effect of stigma on shame in the path model is in line with previous research where illness-related stigma was found to lead to shame.
“Stigma had a large direct effect on shame in the path model, which is in line with previous research where illness-related stigma was found to lead to shame (Akbari, Mohammadi, and Hosseini 2023).”
From Illness Stigma and Shame in People With Chronic Illnesses vs. SARS‐CoV‐2 Survivors: Associations With Psychological Distress Through Psychological Flexibility and Self‐Compassion. (2024) · cites this paper as Akbari, Mohammadi, and Hosseini 2023
Stigma often stems from value conflicts with societal norms, limited knowledge about diseases, and misconceptions about specific disease traits, which increases hesitation to seek medical help.
“Stigma often stems from value conflicts with societal norms, limited knowledge about diseases, and misconceptions about specific disease traits [75], which increases hesitation to seek medical help [76,77,78].”
From Toward Safer Diagnoses: A SEIPS-Based Narrative Review of Diagnostic Errors (2026) · cites this paper as [75]
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- Authors
- Akbari, H., Mohammadi, M., & Hosseini, A.
- Affiliations
- Ferdowsi University of Mashhad (IR)
- Corresponding author
- Akbari, Hossein
- Venue
- Iranian Journal of Public Health
- Publisher
- Knowledge E DMCC
- Published
- 2023-10-14
- Volume
- 52
- Issue
- 10
- Pages
- 2042-2054
- ISSN
- 0304-4556 (ISSN-L)
- 2251-6093
- 2251-6085
- PMC
- PMC10612557
- OpenAlex
- W4387654929
- Cited by
- 26
- References
- 46
- Citations by year
- 2026: 8 · 2025: 16 · 2024: 2
- FWCI
- 7.70
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by-nc
- Locations
- Iranian Journal of Public Health (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Health Sciences › Health Professions › Pharmacy › Obesity and Health Practices
- Keywords
- coping strategies, concealment, lack of knowledge, stigma reduction
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