Adherence to oral anti-diabetic drugs among patients attending a Ghanaian teaching hospital
Open accessAbstract
BACKGROUND: The burden of diabetes mellitus, especially Type-2, continues to increase across the world. Medication adherence is considered an integral component in its management. Poor glycemic controls due to medication nonadherence accelerates the development of long-term complications which consequently leads to increased hospitalization and mortality. OBJECTIVE: This study examined the level of adherence to oral antidiabetic drugs among patients who visited the teaching hospital and explored the probable contributory factors to non-adherence. METHODS: A cross-sectional descriptive study using systematic sampling to collect quantitative data was undertaken. Questionnaires were administered to outpatients of the medical department of a teaching hospital in Ghana. Logistic regression was performed with statistical significance determined at p<0.05. RESULTS: A total of 200 diabetic patients participated in the study. Using the Morisky Medication Adherence scale, the level of adherence determined was 38.5%. There were significant correlations between level of adherence and educational level [(OR)=1.508; (CI 0.805-2.825), P=0.019), and mode of payment [(OR)=1.631; (CI 0.997-2.669), P=0.05). CONCLUSION: Adherence in diabetic patients was low among respondents and this can be improved through education, counseling and reinforcement of self-care. There were several possible factors that contributed to the low adherence rate which could benefit from further studies.
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A handful of quantitative studies have identified age, income, education and gender as demographic factors influencing non-adherence to malaria and diabetic drug treatment.
“A handful of quantitative studies have identified age, income, education and gender as demographic factors influencing non-adherence to malaria and diabetic drug treatment [19].”
From Factors influencing long-term medication non-adherence among diabetes and hypertensive patients in Ghana: A qualitative investigation (2018) · cites this paper as [19]
The Results and Discussion report an association between education and adherence to oral anti-diabetic drugs. But the Results table does not show significant associations for age (p=0.229) or income (p=0.060); gender was collected but not reported as an identified factor. This study concerns diabetic medication, not malaria treatment. (LLM, conf=0.89)
Experimental — accuracy not yet measuredAdherence rates in two Ghanaian settings were 38.5% for diabetes patients and 47.7% for hypertensive patients.
“Studies in two different settings, however, found 38.5% adherence rate among diabetes patients [19] and 47.7% for hypertensive patients [20].”
From Factors influencing long-term medication non-adherence among diabetes and hypertensive patients in Ghana: A qualitative investigation (2018) · cites this paper as [19]
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Economic costs of diabetes in the U.S. in 2007
American Diabetes Association (2008) · Diabetes Care · doi:10.2337/dc08-9017 · Cited by 1,323 · see citing works
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Atinga, R. A., Yarney, L., & Gavu, N. M. (2018) · PLoS ONE · doi:10.1371/journal.pone.0193995 · Cited by 113 · see citing works
- Authors
- Bruce, S. P., Acheampong, F., & Kretchy, I.
- Affiliations
- Korle Bu Teaching Hospital (GH)
- University of Ghana (GH)
- Venue
- Pharmacy Practice
- Publisher
- JCFCorp SG PTE LTD
- Published
- 2015-03-13
- Volume
- 13
- Issue
- 1
- Pages
- 533
- ISSN
- 1885-642X (ISSN-L)
- 1886-3655
- PMC
- PMC4384271
- OpenAlex
- W1540196443
- Cited by
- 52
- References
- 1
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 3 · 2023: 5 · 2022: 8 · 2021: 6 · 2020: 4 · 2019: 6 · 2018: 9 · 2017: 1 · 2016: 3
- FWCI
- 5.06
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by-nc-nd
- Locations
- Pharmacy Practice (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-sa)
- PubMed (publishedVersion)
- Dialnet (Universidad de la Rioja) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Redalyc (Universidad Autónoma del Estado de México) (submittedVersion)
- Scientific Electronic library online (Sciences Carlos III Health Institute) (submittedVersion)
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacy and Medical Practices
- Keywords
- medication adherence, oral antidiabetic drugs, type 2 diabetes, non-adherence factors, educational attainment, payment methods, glycemic control, self-care, Morisky Medication Adherence Scale, Ghana
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