In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers
Open accessPublished version of a preprint
Abstract
Aging | doi:10.18632/aging.204701. Parinya Samakkarnthai, Dominik Saul, Lei Zhang, Zaira Aversa, Madison L. Doolittle, Jad G. Sfeir, Japneet Kaur, Elizabeth J. Atkinson, James R. Edwards, Graham G. Russell, Robert J. Pignolo, James L. Kirkland, Tamar Tchkonia, Laura J. Niedernhofer, David G. Monroe, Nathan K. Lebrasseur, Joshua N. Farr, Paul D. Robbins, Sundeep Khosla
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References 78 · Cited by 34
Research works printed but not linked: 1
- [73]Nowicka M, Krieg C, Crowell HL, Weber LM, Hartmann FJ, Guglietta S, Becher B, Levesque MP, Robinson MD. CyTOF workflow: differential discovery in high-throughput high-dimensional cytometry datasets. F1000Res. 2017; 6: 748. 10.12688/f1000research.11622.3 28663787 PMC5473464 · DOI
- Authors
- Samakkarnthai, P., Saul, D., Zhang, L., Aversa, Z., Doolittle, M. L., Sfeir, J. G., Kaur, J., Atkinson, E. J., Edwards, J. R., Russell, G. G., Pignolo, R. J., Kirkland, J. L., Tchkonia, T., Niedernhofer, L. J., Monroe, D. G., Lebrasseur, N. K., Farr, J. N., Robbins, P. D., & Khosla, S.
- Affiliations
- Mayo Clinic (US)
- University of Minnesota (US)
- University of Oxford (GB)
- Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, OX3 7FY, UK
- Corresponding author
- Khosla, Sundeep
- ORCID
- Venue
- Aging
- Publisher
- Impact Journals, LLC
- Published
- 2023-05-07
- Volume
- 15
- Issue
- 9
- Pages
- 3331-3355
- ISSN
- 1945-4589 (ISSN-L)
- PMC
- PMC10449299
- OpenAlex
- W4372405249
- Cited by
- 34
- References
- 78
- Citations by year
- 2026: 3 · 2025: 11 · 2024: 15 · 2023: 5
- FWCI
- 6.04
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- Aging (publishedVersion, cc-by)
- bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- White Rose Research Online (University of Leeds, The University of Sheffield, University of York) (acceptedVersion)
- PubMed Central (submittedVersion)
- Greater South Information System
- Funders
- Glenn Foundation for Medical Research
- UK Research and Innovation
- Noaber Foundation
- Deutsche Forschungsgemeinschaft (413501650)
- Fondation pour la Recherche Médicale
- National Institutes of Health (AG13925, AG062413)
- Research England
- National Institute on Aging (R01AG063707, R01AG013925, R21AG065868, R37AG013925, U19AG056278, P01AG062413, R01AG076515, R01AG055529)
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK128552)
- Topics
- Health Sciences › Medicine › Physiology › Telomeres, Telomerase, and Senescence
- Health Sciences › Medicine › Oncology › Bone health and treatments
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bone Metabolism and Diseases
- Keywords
- zoledronic acid, cellular senescence, senescence-associated secretory phenotype, bisphosphonates, bone resorption, osteoporosis, in vitro and in vivo effects
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