A first in man phase I trial of the oral immunomodulator, indoximod, combined with docetaxel in patients with metastatic solid tumors
Soliman, Hatem H., Jackson, Erica, Neuger, Tony, Dees, E. Claire, Harvey, R. Donald, Han, Hyo, Ismail-Khan, Roohi, Minton, Susan +4 more·2014·Oncotarget
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- Role of Indoleamine 2,3-Dioxygenase in Acute Myeloid LeukemiaPhilip T. Sobash, Ravindra B Kolhe, Nagla Abdel Karim, Achuta Kumar Guddati, Anand Jillella, Vamsi K Kota · 2020 · Future Oncology
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- Overcoming Therapeutic Resistance by Targeting Cancer InflammationGregory Lawrence Beatty · 2016 · American Society of Clinical Oncology Educational Book
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- Computer‐aided drug design in new druggable targets for the next generation of immune‐oncology therapiesRita C. Acúrcio, Anna Scomparin, Ronit Satchi‐Fainaro, Helena F. Florindo, Rita Cardoso Guedes · 2018 · Wiley Interdisciplinary Reviews Computational Molecular Science
- Indoleamine 2,3-dioxygenase expression in the prognosis of the localized prostate cancerJanaína Mendes Ferreira, Humberto Dellê, Cleber Pinto Camacho, Robson José de Almeida, Sabrina T. Reis, Yves Silva Teles Matos, Amanda M. Ramos Lima, Kátia Ramos Moreira Leite, José Pontes‐Júnior, Miguel Srougi · 2020 · International Urology and Nephrology
- Natural products targeting the metabolism of amino acids: from discovery to synthetic developmentHyun Su Kim, Ahmed H.E. Hassan, Kyuho Moon, Jaehoon Sim · 2025 · Natural Product Reports
- Indoleamine 2,3-dioxygenase 1 in cancer immunotherapy: from small-molecule inhibition to PROTAC-mediated degradationXiuyun Li, Hao Meng, Hefeng Wang, Yujing Zhang, Wanpeng Yu · 2025 · Frontiers in Pharmacology
- Bacterial tryptophan metabolites in cancer and atherosclerosis: insights for a role in immune checkpoint inhibitionThijs Dormans, Jeffrey Kroon, Elena Rampanelli, Max Nieuwdorp, Nick van Es · 2025 · Essays in Biochemistry
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- Medikamentöse Tumortherapie in der Dermato-OnkologieLucie Heinzerling, Anke Hartmann, Martina Hund, Gerold Schuler · 2013 · Springer eBooks
- Indoleamine 2,3-Dioxygenase Activity-Induced Acceleration of Tumor Growth, and Protein Kinases-Related Novel Therapeutics RegimensAyşe Başak Engin, Atilla Engin · 2021 · Advances in experimental medicine and biology
- Design, synthesis and evaluation of tryptophan analogues as tool compounds to study IDO1 activityNicholas J. Cundy, Roseanna K. Hare, Tina Tang, Andrew G. Leach, Thomas A. Jowitt, Omar Qureshi, John C. Gordon, Nicholas M. Barnes, Catherine Brady, Emma Lloyd Raven et al. · 2021 · RSC Chemical Biology
- Comprehensive analysis of the prognostic value and immunological role of IDO1 gene in pan-cancerKaili Lin, Yongfeng Wang, Fangyu Liu, Taifu You, Xiongxiong Liu, Runzhang Liu, Zeyang Li, Chunyu Zhen, Yunxia Zhang, Xingguang Liu et al. · 2024 · European journal of medical research
- Design, Synthesis and Biological Evaluation of Novel 1,2,5-Oxadiazol-3- Carboximidamide Derivatives as Indoleamine 2, 3-Dioxygenase 1 (IDO1) InhibitorsZhifeng Xia, Yanyang Nan, Chang Liu, Guangyu Lin, Kedan Gu, Cheng Chen, Weili Zhao, Dianwen Ju, Xiaochun Dong · 2020 · Anti-Cancer Agents in Medicinal Chemistry
- Metabolic Stress and Immunity: Nutrient-Sensing Kinases and Tryptophan MetabolismJohanna Maria Gostner, Dietmar Fuchs, Katharina Kurz · 2021 · Advances in experimental medicine and biology
- Checkpoint Blockade Immunotherapy for GlioblastomaKatherine A. Riccione, Patrick C. Gedeon, L. Sanchez-Perez, John Howard Sampson · 2017 · Elsevier eBooks
- Combining immunotherapies to treat non-small cell lung cancerAlessia Spagnuolo, Cesare Gridelli · 2019 · Expert Review of Respiratory Medicine
- Indoleamine 2,3-dioxygenaseMichele Coluccia, Daniela Secci, Paolo Guglielmi · 2023 · Elsevier eBooks
- Vaccine Therapy and Immunotherapy for Pancreatic CancerLei Zheng, Elizabeth M. Jaffee · 2018 · Springer eBooks
- Role of Kynurenine Pathway in HIV/AIDSJean‐Pierre Routy, Vikram Mehraj, Kishanda Vyboh · 2015 · Springer eBooks
- Targeting Leukemia Stem Cells and the Immunological Bone Marrow MicroenvironmentCristina Maccalli, Sarah Kathleen Tasian, Sergio Rutella · 2019 · Resistance to targeted anti-cancer therapeutics
- Recent Advancements in Immunotherapy for the Treatment of Metastatic Breast CancerB. Madhu Krishna, Pankaj Garg, Sravani Keerthi Ramisetty, Meera Nair, Sharad S. Singhal · 2025 · Cancer treatment and research
- Modulation of the Kynurenine Pathway: A New Approach for Treating NeurodegenerationJulia K. Banaszkiewicz, Anna Kukiełka, Elżbieta Kudyk, Łucja Justyna Walczak, Katarzyna Wicha-Komsta, Mariola Herbet, Iwona Piątkowska‐Chmiel, Grzegorz Nowicki, Carmen E. Mielnik, Tomasz Kocki · 2026 · Life
- Tryptophan metabolism in tumor immune escape: mechanisms, cellular crosstalk, and therapeutic opportunitiesJingyun Chen, X L Wang, Meiheng Gong, Yufeng Wang, Tingting Yu · 2026 · Frontiers in Immunology
- Clinical Trials Targeting the Kynurenine PathwayMelanie Anne Sheen, Hatem H. Soliman · 2015 · Springer eBooks
- CD4 + T Cells Mediate Dendritic Cell Licensing to Promote Multi‐Antigen Anti‐Leukemic Immune ResponseLuis Gil‐de‐Gómez, Jane Mattei, Jessica Heejong Lee, Stephan A. Grupp, Gregor S. D. Reid, Alix Eden Seif · 2024 · Cancer Medicine
- IDO/TDO Inhibition in CancerGeorge C. Prendergast, William J. Malachowski, Arpita Mondal, Peggy Scherle, Alexander J. Muller · 2017 · Springer eBooks
- Overview of Tumor Immunotherapy based on Indoleamine 2,3 Dioxygenase InhibitorsXiangyu Hao · 2020 · International Conference on Biomedical and Bioinformatics Engineering (ICBBE)
- Checkpoint inhibition in the fight against cancer: NK cells have some to say in itChristian Sordo‐Bahamonde, Seila Lorenzo‐Herrero, Ana Pilar González, Segundo R. Gonzalez · 2021 · Elsevier eBooks
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- Immunothérapie anticancer : les molécules immunomodulatrices en développement cliniqueDelphine Loirat, Christophe Le Tourneau · 2015 · ONCOLOGIE
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- Additional file 1 of Comprehensive analysis of the prognostic value and immunological role of IDO1 gene in pan-cancerLin, Kaili, Wang, Yongfeng, Liu, Fangyu, Taifu You, Liu, Xiongxiong, Runzhang Liu, Li, Zeyang, Zhen, Chunyu, Zhang, Yunxia, Xingguang Liu et al. · 2024 · Figshare
- Additional file 2 of Comprehensive analysis of the prognostic value and immunological role of IDO1 gene in pan-cancerLin, Kaili, Wang, Yongfeng, Liu, Fangyu, Taifu You, Liu, Xiongxiong, Runzhang Liu, Li, Zeyang, Zhen, Chunyu, Zhang, Yunxia, Xingguang Liu et al. · 2024 · Figshare
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- BindingDB Entry 50014283: Design, synthesis and biological evaluation of exiguamine A analogues as IDO1 inhibitors.BindingDB · 2022 · UC San Diego
- BindingDB Entry 50011763: Design, synthesis and biological evaluation of indole-2-carboxylic acid derivatives as IDO1/TDO dual inhibitors.BindingDB · 2022 · UC San Diego
- BindingDB Entry 50014490: Discovery of indoximod prodrugs and characterization of clinical candidate NLG802.BindingDB · 2022 · UC San Diego
- BindingDB Entry 50019139: Recent advances in small molecule based cancer immunotherapy.BindingDB · 2024 · UC San Diego
- BindingDB Entry 50001412: Fragment-based approach to identify IDO1 inhibitor building blocks.BindingDB · 2020 · UC San Diego