Cited by 26Machine Learning in HealthcareElectronic Health Records SystemsMultimodal Machine Learning Applications

How to leverage the multimodal EHR data for better medical prediction?

Open access
Yang, Bo, Wu, Lijun·2021·Proceedings of the 2021 Conference on Empirical Methods in Natural Language Processing

Abstract

Healthcare is becoming a more and more important research topic recently.With the growing data in the healthcare domain, it offers a great opportunity for deep learning to improve the quality of medical service.However, the complexity of electronic health records (EHR) data is a challenge for the application of deep learning.Specifically, the data produced in the hospital admissions are monitored by the EHR system, which includes structured data like daily body temperature, and unstructured data like free text and laboratory measurements.Although there are some preprocessing frameworks proposed for specific EHR data, the clinical notes that contain significant clinical value are beyond the realm of their consideration.Besides, whether these different data from various views are all beneficial to the medical tasks and how to best utilize these data remain unclear.Therefore, in this paper, we first extract the accompanying clinical notes from EHR and propose a method to integrate these data, we also comprehensively study the different models and the data leverage methods for better medical task prediction.The results on two medical prediction tasks show that our fused model with different data outperforms the state-of-the-art method that without clinical notes, which illustrates the importance of our fusion method and the value of clinical note features.Our code is available at https: //github.com/emnlp-mimic/mimic.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.18653/v1/2021.emnlp-main.329

Cites

5 of 5 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Attention mechanisms such as gated attention, cross-attention, or transformer encoders are increasingly adopted in multimodal AI.

    “attention mechanisms such as gated attention [40,41], cross-attention [42–45], or transformer encoders [20,36,46–49] are increasingly adopted.”

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 25

  1. Edward Choi, Mohammad Taha Bahadori, Andy Schuetz, Walter F Stewart, and Jimeng Sun. 2016. Doctor ai: Predicting clinical events via recurrent neural networks. In Machine learning for health- care conference, pages 301-318.
  2. PMLR.
  3. Jia Deng, Wei Dong, Richard Socher, Li-Jia Li, Kai Li, and Li Fei-Fei. 2009. Imagenet: A large-scale hier- archical image database. In 2009 IEEE Conference on Computer Vision and Pattern Recognition, pages 248-255. IEEE Computer Society.
  4. Qipeng Guo, Xipeng Qiu, Pengfei Liu, Yunfan Shao, Xiangyang Xue, and Zheng Zhang. 2019. Star- transformer. In Proceedings of the 2019 Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies, Volume 1 (Long and Short Papers), pages 1315-1325, Minneapolis, Minnesota. Associ- ation for Computational Linguistics. · DOI
  5. Sepp Hochreiter and Jürgen Schmidhuber. 1997. Long short-term memory. Neural computation, 9(8):1735-1780.
  6. Kexin Huang, Jaan Altosaar, and Rajesh Ranganath. 2019. Clinicalbert: Modeling clinical notes and pre- dicting hospital readmission. arXiv:1904.05342. · arXiv
  7. Alistair EW Johnson, Tom J Pollard, Lu Shen, H Lehman Li-Wei, Mengling Feng, Moham- mad Ghassemi, Benjamin Moody, Peter Szolovits, Leo Anthony Celi, and Roger G Mark. 2016. Mimic- iii, a freely accessible critical care database. Scien- tific data, 3(1):1-9.
  8. Yann LeCun, Léon Bottou, Yoshua Bengio, and Patrick Haffner. 1998. Gradient-based learning applied to document recognition. Proceedings of the IEEE, 86(11):2278-2324.
  9. Zhun Liu, Ying Shen, Varun Bharadhwaj Lakshmi- narasimhan, Paul Pu Liang, AmirAli Bagher Zadeh, and Louis-Philippe Morency. 2018. Efficient low- rank multimodal fusion with modality-specific fac- tors. In Proceedings of the 56th Annual Meeting of the Association for Computational Linguistics (Vol- ume 1: Long Papers), pages 2247-2256, Melbourne, Australia. Association for Computational Linguis- tics. · DOI · Paper page
  10. Matouš Macháček and Ondřej Bojar. 2014. Results of the wmt14 metrics shared task. In Proceedings of the Ninth Workshop on Statistical Machine Transla- tion, pages 293-301.
  11. Zhi Qiao, Xian Wu, Shen Ge, and Wei Fan. 2019. Mnn: Multimodal attentional neural networks for diagno- sis prediction. In Proceedings of the Twenty-Eighth International Joint Conference on Artificial Intel- ligence, IJCAI-19, pages 5937-5943. International Joint Conferences on Artificial Intelligence Organi- zation. · DOI
  12. Wasifur Rahman, Md Kamrul Hasan, Sangwu Lee, Amir Zadeh, Chengfeng Mao, Louis-Philippe Morency, and Ehsan Hoque. 2020. Integrating mul- timodal information in large pretrained transformers. In Proceedings of the conference. Association for Computational Linguistics. Meeting, volume 2020, page 2359. NIH Public Access.
  13. Junyuan Shang, Shenda Hong, Yuxi Zhou, Meng Wu, and Hongyan Li. 2018. Knowledge guided multi- instance multi-label learning via neural networks in medicines prediction. In Asian Conference on Ma- chine Learning, pages 831-846.
  14. PMLR.
  15. Junyuan Shang, Cao Xiao, Tengfei Ma, Hongyan Li, and Jimeng Sun. 2019. Gamenet: Graph augmented memory networks for recommending medication combination. In proceedings of the AAAI Confer- ence on Artificial Intelligence, volume 33, pages 1126-1133.
  16. Bonggun Shin, Julien Hogan, Andrew B Adams, Ray- mond J Lynch, Rachel E Patzer, and Jinho D Choi. 2019. Multimodal ensemble approach to incorpo- rate various types of clinical notes for predicting readmission. In 2019 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI), pages 1-4. IEEE.
  17. Shengpu Tang, Parmida Davarmanesh, Yanmeng Song, Danai Koutra, Michael W Sjoding, and Jenna Wiens. 2020. Democratizing ehr analyses with fiddle: a flexible data-driven preprocessing pipeline for struc- tured clinical data. Journal of the American Medical Informatics Association, 27(12):1921-1934.
  18. Ashish Vaswani, Noam Shazeer, Niki Parmar, Jakob Uszkoreit, Llion Jones, Aidan N Gomez, Łukasz Kaiser, and Illia Polosukhin. 2017. Attention is all you need. In Advances in neural information pro- cessing systems, pages 5998-6008.
  19. Ruoxi Wang, Rakesh Shivanna, Derek Zhiyuan Cheng, Sagar Jain, Dong Lin, Lichan Hong, and Ed Chi. 2021. DCN V2: improved deep & cross network and practical lessons for web-scale learning to rank systems. In WWW '21: The Web Conference 2021, Virtual Event / Ljubljana, Slovenia, April 19-23, 2021, pages 1785-1797. ACM / IW3C2. · DOI
  20. Shirly Wang, Matthew BA McDermott, Geeticka Chauhan, Marzyeh Ghassemi, Michael C Hughes, and Tristan Naumann. 2020. Mimic-extract: A data extraction, preprocessing, and representation pipeline for mimic-iii. In Proceedings of the ACM Conference on Health, Inference, and Learning, pages 222-235.
  21. Yansen Wang, Ying Shen, Zhun Liu, Paul Pu Liang, Amir Zadeh, and Louis-Philippe Morency. 2019. Words can shift: Dynamically adjusting word repre- sentations using nonverbal behaviors. In Proceed- ings of the AAAI Conference on Artificial Intelli- gence, volume 33, pages 7216-7223.
  22. Yonghui Wu, Mike Schuster, Zhifeng Chen, Quoc V Le, Mohammad Norouzi, Wolfgang Macherey, Maxim Krikun, Yuan Cao, Qin Gao, Klaus Macherey, et al. 2016. Google's neural machine translation system: Bridging the gap between hu- man and machine translation. arXiv preprint arXiv:1609.08144. · arXiv
  23. Yanbo Xu, Siddharth Biswal, Shriprasad R Deshpande, Kevin O Maher, and Jimeng Sun. 2018. Raim: Re- current attentive and intensive model of multimodal patient monitoring data. In Proceedings of the 24th ACM SIGKDD international conference on Knowl- edge Discovery & Data Mining, pages 2565-2573.
  24. Jinsung Yoon, Yao Zhang, James Jordon, and Mihaela van der Schaar. 2020. Vime: Extending the success of self-and semi-supervised learning to tabular do- main. In Advances in Neural Information Process- ing Systems, volume 33, pages 11033-11043.
  25. Amir Zadeh, Minghai Chen, Soujanya Poria, Erik Cam- bria, and Louis-Philippe Morency. 2017. Tensor fusion network for multimodal sentiment analysis. In Proceedings of the 2017 Conference on Empiri- cal Methods in Natural Language Processing, pages 1103-1114, Copenhagen, Denmark. Association for Computational Linguistics. · DOI · Paper page

Cited by

Sorted by citations

Authors
Yang, B., & Wu, L.
Affiliations
Microsoft Research Asia (China) (CN)
Corresponding author
Wu, Lijun
Venue
Proceedings of the 2021 Conference on Empirical Methods in Natural Language Processing
Published
2021
Pages
4029-4038
OpenAlex
W4205464244
Cited by
26
References
5
Citations by year
2026: 2 · 2025: 10 · 2024: 8 · 2023: 3 · 2022: 3
FWCI
1.62
Type
conference paper
Language
en
Open access
Licence
cc-by
Locations
Conference on Empirical Methods in Natural Language Processing (EMNLP) (publishedVersion, cc-by)
Funders
National Natural Science Foundation of China (U1711263)
Topics
  • Physical Sciences › Computer Science › Artificial Intelligence › Machine Learning in Healthcare
  • Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
  • Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Multimodal Machine Learning Applications
Keywords
electronic health records, multimodal fusion, clinical notes, clinical text extraction, medical prediction, hospital admission data, structured and unstructured data, MIMIC dataset

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review