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Deep Learning and Its Applications in Computational Pathology
Open accessPreprint — published as 10.3390/biomedinformatics2010010 · Paper page
Abstract
Deep learning techniques, such as convolutional neural networks (CNN), generative adversarial networks (GAN), and graph neural networks (GNN), have over the past decade changed the ac-curacy of prediction in many diverse fields. In recent years, the application of deep learning tech-niques in computer vision tasks in pathology demonstrated extraordinary potential in assisting clinicians, automating diagnosis, and reducing costs for patients. Formerly unknown pathologi-cal evidence, such as morphological features related to specific biomarkers, copy number varia-tions, and other molecular features, were also able to be captured by deep learning models. In this paper, we review popular deep learning methods and some recent publications about their appli-cations in pathology.
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Cites
Highly accurate protein structure prediction with AlphaFold
Jumper, J., Evans, R., Pritzel, A., Green, T., Figurnov, M., Ronneberger, O., Tunyasuvunakool, K., Bates, R., Žídek, A., Potapenko, A., et al. (2021) · Nature · doi:10.1038/s41586-021-03819-2 · Cited by 43,764
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Metadata
- Authors
- Hong, R., & Fenyö, D.
- Affiliations
- New York University (US)
- Corresponding author
- Hong, Runyu
- Fenyö, David
- Venue
- BioMedInformatics
- Publisher
- MDPI AG
- Published
- 2022-01-17
- Volume
- 2
- Issue
- 1
- Pages
- 159-168
- ISSN
- 2673-7426 (ISSN-L)
- OpenAlex
- W4225488857
- Cited by
- 13
- References
- 1
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 2 · 2023: 5 · 2022: 1
- FWCI
- 0.82
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- BioMedInformatics (publishedVersion, cc-by)
- Preprints.org (acceptedVersion, cc-by)
- Funders
- National Institutes of Health
- National Cancer Institute (U24CA210972)
- Topics
- Physical Sciences › Computer Science › Artificial Intelligence › AI in cancer detection
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiomics and Machine Learning in Medical Imaging
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Keywords
- deep learning, computational pathology, convolutional neural networks, generative adversarial networks, graph neural networks, automated diagnosis, biomarker detection, copy number variation, computer-aided diagnosis, histopathology image analysis
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