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Cited by 44Cardiac Imaging and DiagnosticsLung Cancer Diagnosis and TreatmentMedical Imaging and Pathology Studies

Coronary artery calcification in lung cancer screening

Open access
Ravenel, James G., Nance, John W.·2018·Translational Lung Cancer Research
DOI 10.21037/tlcr.2018.05.05PMC PMC6037959
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Abstract

Lung cancer screening has been shown in the National Lung Screening Trial (NLST) to result in a statistically significant decrease in lung cancer specific mortality. Also within that trial there was shown to be a 7% decrease in all-cause mortality. While the reasons for this benefit are not entirely clear, it may relate to the detection and treatment of other important findings. Smokers not only have a higher risk of lung cancer, but also increased risk of atherosclerosis. The latter can be detected by the discovery of aortic and/or coronary artery calcium on unenhanced CT. As coronary artery calcium scoring can be used as a screening tool to detect asymptomatic coronary artery atherosclerosis, its detection on lung cancer screening exams has the potential to provide both a teachable moment and treatment aimed at the reduction of major coronary artery events and mortality. In this review we will discuss the use of coronary artery calcium scoring for the detection of atherosclerotic disease and its potential application to lung cancer screening populations.

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  • Showing patients their coronary calcium provides a teachable moment to empower informed decisions and improve long-term compliance for preventative therapy and lifestyle changes including smoking cessation.

    “Additionally, showing patients their coronary calcium provides a “teachable moment” to empower them to make informed, individualized decisions, and to improve long-term compliance for preventative therapy and lifestyle changes including smoking cessation11,12.”

    From Deep convolutional neural networks to predict cardiovascular risk from computed tomography (2021) · cites this paper as [11]

    The Introduction describes coronary-risk counselling as a teachable moment that can lead to lifestyle changes or improved pharmacological management. The Conclusions and recommendations also call for discussing CT findings with patients. Neither passage establishes that showing patients their calcium improves long-term adherence to preventive therapy or smoking cessation. (LLM, conf=0.87)

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Cited by

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Authors
Ravenel, J. G., & Nance, J. W.
Affiliations
Medical University of South Carolina (US)
Corresponding author
Ravenel, James G.
ORCID
Nance, John W.
Venue
Translational Lung Cancer Research
Publisher
AME Publishing Company
Published
2018-06
Volume
7
Issue
3
Pages
361-367
ISSN
  • 2218-6751 (ISSN-L)
  • 2226-4477
DOI
10.21037/tlcr.2018.05.05
PMC
PMC6037959
OpenAlex
W2806160584
Cited by
44
References
0
Citations by year
2026: 4 · 2025: 6 · 2024: 4 · 2023: 3 · 2022: 4 · 2021: 11 · 2020: 8 · 2019: 3 · 2018: 1
FWCI
0.90
Type
journal article
Language
en
Open access
Licence
cc-by-nc-nd
Locations
  • Translational Lung Cancer Research (publishedVersion, cc-by-nc-nd)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Lung Cancer Diagnosis and Treatment
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Medical Imaging and Pathology Studies
Keywords
coronary artery calcification, coronary artery calcium scoring, lung cancer screening, atherosclerosis, smokers, National Lung Screening Trial, all-cause mortality, coronary artery disease

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