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Mortality of intravenous drug users in Rome: a cohort study.

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Perucci, C A, Davoli, M, Rapiti, E, Abeni, D D, Forastiere, F·1991·American Journal of Public Health

Abstract

A historical cohort study was carried out in Rome to examine overall and cause-specific mortality among intravenous drug users (IVDUs). A total of 4200 IVDUs (3411 men and 789 women) enrolled in methadone treatment centers between 1980 and 1988 were studied. There were 239 deaths during the follow-up period. The overall SMR was 10.10 in the entire cohort (95% confidence interval, 8.86-11.47), 9.30 in males and 18.07 in females. A large excess of mortality in both sexes was found for infectious, circulatory, respiratory, and digestive diseases as well as for violence, overdose, AIDS, and unknown or ill-defined causes. Tumors and suicide were excessive only in males. Deaths due to drug overdose, violence or trauma, and cirrhosis accounted for 63.6%, AIDS for 7.1%, endocarditis and other bacterial infections for 7.1%, and neoplasms for 3.8% of total mortality. These findings document serious health consequences of drug abuse in Italy.

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Metadata

Authors
Perucci, C. A., Davoli, M., Rapiti, E., Abeni, D. D., & Forastiere, F.
Venue
American Journal of Public Health
Published
1991-10
Volume
81
Issue
10
Pages
1307-1310
ISSN
  • 0090-0036 (ISSN-L)
  • 1541-0048
OpenAlex
W2080330936
Cited by
158
References
0
FWCI
5.92
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Mortality of intravenous drug users in Rome: a cohort study. https://app.cochat.ai/papers/10.2105/ajph.81.10.1307
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Perucci, C. A., Davoli, M., Rapiti, E., Abeni, D. D., & Forastiere, F. (1991). Mortality of intravenous drug users in Rome: a cohort study. American Journal of Public Health. https://doi.org/10.2105/ajph.81.10.1307

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.