Plain Radiography and Magnetic Resonance Imaging Diagnostics in Osteoarthritis: Validated Staging and Scoring
Abstract
Osteoarthritis is the most common joint disorder worldwide, and it has an enormous socioeconomic impact both in the United States and throughout the world. Conventional radiography is the simplest and least expensive imaging method for assessing osteoarthritis of the knee. Radiography is able to directly visualize osseous features of osteoarthritis, including marginal osteophytes, subchondral sclerosis, and subchondral cysts, and it is used in clinical practice to confirm the diagnosis of osteoarthritis and to monitor progression of the disease. However, the assessment of joint-space width provides only an indirect estimate of cartilage thickness and meniscal integrity. Magnetic resonance imaging, with its unique ability to examine the joint as a whole organ, holds great promise with regard to the rapid advancement of knowledge about the disease and the evaluation of novel treatment approaches. Magnetic resonance imaging has been applied widely in quantitative morphometric cartilage assessment, and compositional measures have been introduced that evaluate chondral integrity. In addition, magnetic resonance imaging-based validated semiquantitative whole-organ scoring methods have been applied for cross-sectional and longitudinal joint evaluation. This review describes currently applied radiographic and magnetic resonance imaging staging and scoring methods for the assessment of osteoarthritis of the knee and focuses on the strengths and weaknesses of the two modalities with re…
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Traditional diagnostic techniques depend on radiography results that become evident only after significant tissue damage has occurred.
“Often, in cases where treatment procedures have limited effectiveness, traditional diagnostic techniques depend on radiography results that become evident only after significant tissue damage has occurred [5].”
From Biomarker-Guided Imaging and AI-Augmented Diagnosis of Degenerative Joint Disease (2025) · cites this paper as [5]
Early diagnosis of degenerative joint disease poses a significant clinical challenge because of its gradual onset and symptom overlap with other musculoskeletal disorders.
“Degenerative joint disease remains a leading cause of global disability, with early diagnosis posing a significant clinical challenge due to its gradual onset and symptom overlap with other musculoskeletal disorders.”
From Biomarker-Guided Imaging and AI-Augmented Diagnosis of Degenerative Joint Disease (2025) · cites this paper as [5]
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Glyn-Jones, S., Palmer, A. J. R., Agricola, R., Price, A. J., Vincent, T. L., Weinans, H., & Carr, A. J. (2015) · The Lancet · doi:10.1016/s0140-6736(14)60802-3 · Cited by 3,151 · see citing works
Biomarker-Guided Imaging and AI-Augmented Diagnosis of Degenerative Joint Disease
Kumar, R., Sporn, K., Borole, A., Khanna, A., Gowda, C., Paladugu, P., Ngo, A., Jagadeesan, R., Zaman, N., & Tavakkoli, A. (2025) · Diagnostics · doi:10.3390/diagnostics15111418 · Cited by 10 · see citing works
“Often, in cases where treatment procedures have limited effectiveness, traditional diagnostic techniques depend on radiography results that become evident only after significant tissue damage has occurred [5].”
- Authors
- Guermazi, A., Hunter, D. J., & Roemer, F. W.
- Affiliations
- Boston Medical Center (US)
- New England Baptist Hospital (US)
- Venue
- Journal of Bone and Joint Surgery
- Published
- 2009-02-01
- Volume
- 91
- Issue
- Supplement_1
- Pages
- 54-62
- ISSN
- 0021-9355 (ISSN-L)
- 1535-1386
- OpenAlex
- W2152628528
- Cited by
- 81
- References
- 0
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 9 · 2023: 4 · 2022: 1 · 2021: 3 · 2020: 1 · 2019: 3 · 2018: 3 · 2017: 4 · 2015: 4 · 2014: 7 · 2013: 8 · 2012: 6
- FWCI
- 5.90
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Bone and Joint Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Rheumatology › Osteoarthritis Treatment and Mechanisms
- Health Sciences › Medicine › Surgery › Knee injuries and reconstruction techniques
- Health Sciences › Medicine › Surgery › Hip disorders and treatments
- Keywords
- knee osteoarthritis, radiography, magnetic resonance imaging, cartilage assessment, joint space width, subchondral sclerosis, osteophytes, subchondral cysts, cartilage thickness, disease progression
- MeSH terms
- Humans, Magnetic Resonance Imaging, Radiography, Osteoarthritis, Knee
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