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PreprintCited by 16Venomous Animal Envenomation and StudiesMarine Biology and Ecology ResearchMarine Invertebrate Physiology and Ecology

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Coordinated adaptations define the ontogenetic shift from worm- to fish-hunting in a venomous cone snail

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Rogalski, Aymeric, S.W.A., Himaya, Lewis, Richard·2022·Nature Communications
DOI 10.21203/rs.3.rs-2153130/v1PMC PMC10264353

Preprint — published as 10.1038/s41467-023-38924-5

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Abstract

Marine cone snails have attracted researchers from all disciplines but early life stages have received limited attention due to difficulties accessing or rearing juvenile specimens. Here, we document for the first time the culture of Conus magus from eggs through metamorphosis to reveal dramatic shifts in predatory feeding behaviour between post-metamorphic juveniles and adult specimens. Adult C. magus capture fish using a set of paralytic venom peptides combined with a hooked radular tooth used to tether envenomed fish. In contrast, early juveniles feed exclusively on polychaete worms using a unique “sting-and-stalk” foraging behaviour facilitated by short, unbarbed radular teeth and a distinct venom repertoire that induces hypoactivity in prey. Our results demonstrate how coordinated morphological, behavioural and molecular changes facilitate the shift from worm- to fish-hunting in C. magus, and showcase juvenile cone snails as a rich and unexplored source of novel venom peptides for ecological, evolutionary and biodiscovery studies.

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Metadata

Authors
Rogalski, A., S.W.A., H., & Lewis, R.
Affiliations
  • The University of Queensland (AU)
  • The University of Queensland
Corresponding author
Lewis, Richard
ORCID
Venue
Nature Communications
Publisher
Springer Science and Business Media LLC
Published
2022-10-18
Volume
14
Issue
1
Pages
3287-3287
ISSN
2041-1723 (ISSN-L)
DOI
10.21203/rs.3.rs-2153130/v1
PMC
PMC10264353
OpenAlex
W4380480295
Cited by
16
References
1
Citations by year
2026: 4 · 2025: 5 · 2024: 6 · 2023: 1
FWCI
2.65
Type
journal article
Language
en
Open access
Licence
Locations
  • Nature Communications (publishedVersion, cc-by)
  • Research Square (acceptedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • RePEc: Research Papers in Economics (submittedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • University of Queensland
  • Department of Education and Training (DP200103087)
  • Australian Research Council (DP200103087)
Topics
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Venomous Animal Envenomation and Studies
  • Physical Sciences › Earth and Planetary Sciences › Oceanography › Marine Biology and Ecology Research
  • Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Marine Invertebrate Physiology and Ecology
Keywords
Conus magus, Conidae, ontogenetic shifts, venom peptides, radular teeth, Polychaeta, fish predation, juvenile development, metamorphosis, prey capture, venom evolution, marine gastropods
MeSH terms
Acclimatization, Animals, Eggs, Biological Evolution, Fishes, Metamorphosis, Biological, Predatory Behavior, Hepatophyta

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