The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Size-dependent antimicrobial properties of CuO nanoparticles against Gram-positive and -negative bacterial strains
Open accessAbstract
BACKGROUND: CuO is one of the most important transition metal oxides due to its captivating properties. It is used in various technological applications such as high critical temperature superconductors, gas sensors, in photoconductive applications, and so on. Recently, it has been used as an antimicrobial agent against various bacterial species. Here we synthesized different sized CuO nanoparticles and explored the size-dependent antibacterial activity of each CuO nanoparticles preparation. METHODS: CuO nanoparticles were synthesized using a gel combustion method. In this approach, cupric nitrate trihydrate and citric acid were dissolved in distilled water with a molar ratio of 1:1. The resulting solution was stirred at 100°C, until gel was formed. The gel was allowed to burn at 200°C to obtain amorphous powder, which was further annealed at different temperatures to obtain different size CuO nanoparticles. We then tested the antibacterial properties using well diffusion, minimum inhibitory concentration, and minimum bactericidal concentration methods. RESULTS: XRD spectra confirmed the formation of single phase CuO nanoparticles. Crystallite size was found to increase with an increase in annealing temperature due to atomic diffusion. A minimum crystallite size of 20 nm was observed in the case of CuO nanoparticles annealed at 400°C. Transmission electron microscopy results corroborate well with XRD results. All CuO nanoparticles exhibited inhibitory effects against both Gram-positive and -negative bacteria. The size of the particles was correlated with its antibacterial activity. CONCLUSION: The antibacterial activity of CuO nanoparticles was found to be size-dependent. In addition, the highly stable minimum-sized monodispersed copper oxide nanoparticles synthesized during this study demonstrated a significant increase in antibacterial activities against both Gram-positive and -negative bacterial strains.
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Cited by
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Akintelu, S. A., Folorunso, A. S., Folorunso, F. A., & Oyebamiji, A. K. (2020) · Heliyon · doi:10.1016/j.heliyon.2020.e04508 · Cited by 482
RetractedKhezerlou, A., Alizadeh-Sani, M., Azizi-Lalabadi, M., & Ehsani, A. (2018) · Microbial Pathogenesis · doi:10.1016/j.micpath.2018.08.008 · Cited by 404
Antibacterial Activity of TiO2 Nanoparticles Prepared by One-Step Laser Ablation in Liquid
Khashan, K. S., Sulaiman, G. M., Abdulameer, F. A., Albukhaty, S., Ibrahem, M. A., Al-Muhimeed, T., & AlObaid, A. A. (2021) · Applied Sciences · doi:10.3390/app11104623 · Cited by 182
Antibacterial Activity of TiO2- and ZnO-Decorated with Silver Nanoparticles
Nguyen, V., Vu, V., Nguyen, T., Nguyen, T., Tran, V., & Nguyen-Tri, P. (2019) · Journal of Composites Science · doi:10.3390/jcs3020061 · Cited by 144
Metadata
- Authors
- Azam, A.
- Venue
- International Journal of Nanomedicine
- Publisher
- Informa UK Limited
- Published
- 2012-07
- Volume
- 7
- Pages
- 3527
- ISSN
- 1176-9114 (ISSN-L)
- 1178-2013
- OpenAlex
- W2020458316
- Cited by
- 870
- References
- 19
- FWCI
- 10.14
- Type
- journal article
- Language
- en
- Open access
- gold
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