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Biomedical applications of functionalized fullerene-based nanomaterials
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Biomedical applications of functionalized fullerene-based nanomaterials Ranga Partha, Jodie L ConyersCenter for Translational Injury Research, The University of Texas Health Science Center, Houston, TX 77030, USAAbstract: Since their discovery in 1985, fullerenes have been investigated extensively due to their unique physical and chemical properties. In recent years, studies on functionalized fullerenes for various applications in the field of biomedical sciences have seen a significant increase. The ultimate goal is towards employing these functionalized fullerenes in the diagnosis and therapy of human diseases. Functionalized fullerenes are one of the many different classes of compounds that are currently being investigated in the rapidly emerging field of nanomedicine. In this review, the focus is on the three categories of drug delivery, reactive oxygen species quenching, and targeted imaging for which functionalized fullerenes have been studied in depth. In addition, an exhaustive list of the different classes of functionalized fullerenes along with their applications is provided. We will also discuss and summarize the unique approaches, mechanisms, advantages, and the aspect of toxicity behind utilizing functionalized fullerenes for biomedical applications.Keywords: fullerenes, functionalized fullerenes, nanomedicine, drug delivery, buckysomes, radiation protection
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Kroto, H. W., Allaf, A. W., & Balm, S. P. (1991) · Chemical Reviews · doi:10.1021/cr00006a005 · Cited by 1,088
Cited by
Georgakilas, V., Perman, J. A., Tucek, J., & Zboril, R. (2015) · Chemical Reviews · doi:10.1021/cr500304f · Cited by 2,147
Biju, V. (2014) · Chem. Soc. Rev. · doi:10.1039/c3cs60273g · Cited by 1,186
Nanomedicine(s) under the Microscope
Duncan, R., & Gaspar, R. (2011) · Molecular Pharmaceutics · doi:10.1021/mp200394t · Cited by 981
Controlled drug release from pharmaceutical nanocarriers
Lee, J. H., & Yeo, Y. (2015) · Chemical Engineering Science · doi:10.1016/j.ces.2014.08.046 · Cited by 628
Targeted therapy using nanotechnology: focus on cancer
Sechi, M., Sanna, V., & Pala, N. (2014) · International Journal of Nanomedicine · doi:10.2147/ijn.s36654 · Cited by 493
Metadata
- Authors
- Conyers, J.
- Venue
- International Journal of Nanomedicine
- Publisher
- Informa UK Limited
- Published
- 2009-11
- Volume
- 4
- Pages
- 261
- ISSN
- 1176-9114 (ISSN-L)
- 1178-2013
- OpenAlex
- W2079464363
- Cited by
- 274
- References
- 1
- FWCI
- 9.26
- Type
- journal article
- Language
- en
- Open access
- gold
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