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Cited by 12Fibromyalgia and Chronic Fatigue Syndrome ResearchPsychosomatic Disorders and Their TreatmentsMusculoskeletal pain and rehabilitation

Evaluating the Effect of Delayed Diagnosis on Disease Outcome in Fibromyalgia: A Multi-Center Cross-Sectional Study

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Moshrif, Abdelhfeez, Mosallam, Ahmed, Abu-Zaid, Mohammed Hassan, Gouda, Wesam·2023·Journal of Pain Research
DOI 10.2147/jpr.s381314PMC PMC10132293
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Abstract

Background: The impact of delayed diagnosis (DD) on fibromyalgia (FM) patients' symptomatology and disease outcome has not yet been systematically studied. Objective: To analyze the predictors of DD and the influence of DD on FM aggravation and disease evaluation measures. Methods: 370 FM patients were interviewed prospectively for this study. The following information was obtained: DD, widespread pain index (WPI), symptom severity scale (SSS), polysymptomatic distress scale (PDS) scale (SSS + WPI), and tender points. We identified three groups of patients: early diagnosis (ED: 2 years; 83 patients), late diagnosis (LD: > 2-7 years; 198 patients), and very late diagnosis (VLD: > 7 years; 89 patients). Results: The patients' average age was 33.9 (9.8) years, and 79% were female. The SSS, PDS, and tender point means were 7.8 (1.6), 16.46 (4.1), and 14.31 (2.3), respectively. The correlation between DD and SSS (r = 0.14), the PDS scale (r = 0.37), and FM tender points (r = 0.16) was significant, but not with WPI (r = 0.06). When the three groups were examined, the SSS mean was 7.54 (1.6), 7.73 (1.4), and 8.25 (1.7), respectively (P 0.008), while the PDS mean was 15 (3.8), 15.95 (3.8), and 18.96 (4.4), respectively (P 0.008). (P 0.001). Conclusion: Early FM diagnosis is associated with lower SSS, total severity scale, and FM tender points, indicating a less severe condition.

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Cited by

Sorted by citations

Authors
Moshrif, A., Mosallam, A., Abu-Zaid, M. H., & Gouda, W.
Affiliations
  • Al-Azhar University (EG)
  • Tanta University (EG)
Corresponding author
Moshrif, Abdelhfeez
ORCID
Venue
Journal of Pain Research
Publisher
Informa UK Limited
Published
2023-04
Volume
Volume 16
Pages
1355-1365
ISSN
1178-7090 (ISSN-L)
DOI
10.2147/jpr.s381314
PMC
PMC10132293
OpenAlex
W4366769542
Cited by
12
References
3
Citations by year
2026: 3 · 2025: 4 · 2024: 5
FWCI
2.44
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Pain Research (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • Dove Medical Press (Taylor and Francis Group) (submittedVersion, cc-by-nc)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
  • Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
  • Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
Keywords
fibromyalgia, delayed diagnosis, disease outcome, symptom severity, tender points, Widespread Pain Index, symptom severity scale, early diagnosis

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