Management of Treatment-Resistant Depression: Challenges and Strategies

Voineskos, Daphne, Daskalakis, Zafiris J, Blumberger, Daniel M.·2020·Neuropsychiatric Disease and Treatment

DOI 10.2147/ndt.s198774

Cited by (448)

Items 201–300 of 448

Comparison of effectiveness and side effects of selegiline transdermal system versus oral monoamine oxidase inhibitors and tricyclic antidepressants for treatment-resistant depression
Thomas T. Kim, Colin Xu, Jay D. Amsterdam · 2025 · Journal of Affective Disorders
The antidepressant potential of (2R,6R)-hydroxynorketamine: A detailed review of pre-clinical findings
Isis Rita Anzel Koutrouli, Kristýna Mazochová, Rachel R. Horsley · 2025 · European Journal of Pharmacology
Lack of early reduction in depression severity predicts treatment non-response with 10 Hz and accelerated theta burst repetitive transcranial magnetic stimulation in treatment-resistant depression
Quoc Khoa David Nguyen, Pravik Solanki, Elizabeth H. X. Thomas, Andris Cerins, Lisa Anne Hahn, Cherrie Ann Galletly, Paul Bernard Fitzgerald, Leo Chen · 2025 · Journal of Affective Disorders
Sleep biomarkers for stress-induced vulnerability to depression
Damien Claverie, Chrystel Becker, Antoine Ghestem, Mathieu Coutan, Christophe Bernard, Marion Trousselard, J.J. Benoliel, Frédéric Canini · 2023 · SLEEP
Which clinical factors and biochemical parameters are associated with late-life major depression?
Massimiliano Buoli, Francesca Legnani, Guido Nosari, Anna Pan, Valentina Ciappolino, Cecilia Maria Esposito, Alessandro Ceresa, Martina Di Paolo, Teresa Surace, Anna Maria Auxilia et al. · 2023 · International Journal of Psychiatry in Clinical Practice
Indirect adjusted comparison of 6-month clinical outcomes between esketamine nasal spray and other real-world polypharmacy treatment strategies for treatment resistant depression: results from the ICEBERG study
A. Oliveira-Maia, B. Rive, Joachim Morrens, Y. Godinov, Jedelyn Cabrieto, N. Perualila, S. Mulhern-Haughey · 2023 · Frontiers in Psychiatry
Online mindfulness-based cognitive therapy for treatment-resistant depression: a parallel-arm randomized controlled feasibility trial
Michele Ferreira Rodrigues, Laiana A. Quagliato, José Carlos Appolinário, Antônio Egídio Nardi · 2024 · Frontiers in Psychology
A systematic review and meta-analysis of the preclinical and clinical results of low-field magnetic stimulation in cognitive disorders
Nicholas Mellon, Brett Robbins, Rebekah van Bruggen, Yanbo Zhang · 2024 · Reviews in the Neurosciences
Role of Genetic and Epigenetic Biomarkers in Treatment-Resistant Depression: A Literature Review
Petra Sulić, Andrea Ražić Pavičić, Biljana Đapić Ivančić, Tamara Božina, Nada Božina, Maja Živković · 2025 · Genes
Utilization of psychotherapy, pharmacotherapy, and their combination by individuals with current or residual depression: results from five annual nationally representative German surveys
Louisa Breuer, Andreas Czaplicki, Ulrich Hegerl, Hanna Reich · 2025 · Scientific Reports
Comparison of Effects of Propofol Combined with Different Doses of Esketamine for ECT in the Treatment of Depression: A Randomized Controlled Trial Protocol
Xuemeng Chen, Rui Zhou, Lan Lan, Ling Zhu, Cheng Chen, Xianjie Zhang, Jia Han, Leqiang Xia · 2024 · Neuropsychiatric Disease and Treatment
Antipsychotic therapy and suicide risk in patients with treatment-resistant depression: target trial emulation framework study
Daniel Hsiang‐Te Tsai, Avery Shuei‐He Yang, Zi-Xuan Wong, Albert Tzu-Ming Chuang, Michael Chun‐Yuan Cheng, Chin‐Yao Shen, Shih‐Chieh Shao, Edward Chia‐Cheng Lai · 2025 · The British Journal of Psychiatry
Can ketamine therapy overcome treatment-resistant depression in Alzheimer's disease and older adults? Preclinical and clinical evidence
Altamura Mario, Ivana Leccisotti, Moretti Maria Claudia, Antonello Bellomo, Francesco Panza, Cassano Tommaso, Lozupone Madia · 2025 · Biomedicine & Pharmacotherapy
Long-term outcomes of single-dose psilocybin for U.S. military Veterans with severe treatment-resistant depression – 12-month data from an open-label pilot study
Sara Ellis, Catherine M. Bostian, Anna J. Donnelly, Wendy Feng, Katherine Eisen, Melanie Lean, Elizabeth Conlan, Michael Joshua Ostacher, Scott T. Aaronson, Trisha M Suppes · 2025 · Journal of Affective Disorders
The Role of Fatty Acid Binding Proteins in Neuropsychiatric Diseases: A Narrative Review
Aidan Powell, Noa Yamaguchi, Huy Lu, Ojas Pareek, Igor Elman, Mark S. Gold, Albert Pinhasov, Kenneth Blum, Panayotis K. Thanos · 2025 · Frontiers in Bioscience-Landmark
Mitigating the Risk of Adverse Effects Related to Augmentation Therapy for Resistant Major Depressive Disorder: A Case Report
Collin J. Amundson, Robert Knight, Georgina Ybarra, Jacques Turgeon, Jennifer M. Bingham · 2022 · Medicina
Experience of Stanford neuromodulation therapy in patients with treatment-resistant depression
Alexandra G. Poydasheva, Ilya S. Bakulin, Dmitry O. Sinitsyn, Alfiia Kh. Zabirova, Natalia A. Suponeva, Nikita Maslenikov, Цукарзи Эдуард Эдуардович, Sergey N Mosolov, М. А. Пирадов · 2022 · Bulletin of Russian State Medical University
Salvianolic Acids Alleviate Chronic Mild Stress-Induced Depressive-Like Behaviors in Rats
Fengya Zhen, Lulu Yu, Lan Wang, Shuo Wang, Wenting Lu, Xueyi Wang, Cuixia An · 2023 · Journal of Integrative Neuroscience
Treatment-resistant depression in children and adolescents
Jung-Chi Chang, Hai-Ti-Lin, Yen-Ching Wang, Susan Shur‐Fen Gau · 2023 · Progress in brain research
Evaluation, Treatment, and Referral of Treatment-Resistant Depression in Primary Care
Amit Chopra, James Luccarelli, Jonah N. Cohen, David Mischoulon, Theodore A. Stern · 2023 · The Primary Care Companion For CNS Disorders
ADHD Patients with Suicidal Behaviour: Risk Factors, Comorbidities, and Clinical Profile: A Naturalistic Exploratory Study
Bryan Diaz-Piedra, Joseph R. Sadek · 2024 · Brain Sciences
Treatment Patterns, Acute Healthcare Resource Use, and Costs of Patients with Treatment-Resistant Depression Completing Induction Phase of Esketamine in the United States
Lisa Harding, Kruti Joshi, Maryia Zhdanava, Aditi Shah, Arthur Voegel, Cindy Chen, Dominic Pilon · 2024 · Drugs - Real World Outcomes
Towards New Methodology for Cross-Validation of Clinical Evaluation Scales and Functional MRI in Psychiatry
Diyana Najar, Julian Dichev, Drozdstoy Stoyanov · 2024 · Journal of Clinical Medicine
Neuroprotective Efficacy and Complementary Treatment with Medicinal Herbs: A Comprehensive Review of Recent Therapeutic Approaches in Epilepsy Management
Amit Anand, Aman Shrivastava, Kuldeep Singh, Rakesh Kumar Barik, Devshree Gayakwad, S. Jailani, Shamim Khan, Sumeet Dwivedi · 2024 · CNS & Neurological Disorders - Drug Targets
Neurobiological Mechanisms Underlying Psychological Dysfunction After Brain Injuries
Prashin Unadkat, Tania J Rebeiz, Erum Ajmal, Vincent De Souza, Angela Xia, Julia Jinu, Keren Powell, Chunyan Li · 2025 · Cells
Case report: delayed response after electroconvulsive therapy in a patient with major depressive disorder
Fangyue Chen, Emad Sidhom, Sharon Yang, Eladia Ruiz‐Mendoza, Julius Essem · 2021 · BMC Psychiatry
Deletion or inhibition of prolyl oligopeptidase blocks lithium‐induced phosphorylation of GSK3b and Akt by activation of protein phosphatase 2A
Timo T. Myöhänen, Freke Mertens, Susanna Norrbacka, Hengjing Cui · 2021 · Basic & Clinical Pharmacology & Toxicology
In silico study of dimethyltryptamine analogues against 5-HT1B receptor: Molecular docking, dynamic simulations and ADMET prediction
Neyder Contreras‐Puentes, Antistio Alviz Amador, Isabella Manzur-Villalobos · 2022 · Journal of Herbmed Pharmacology
Ketamine for resistant depression: a scoping review.
Tuta-Quintero Eduardo, Dra. Ángela Acero-González, León Mateo, López-Zuleta Melanie, Prieto-Fernández Valentina, Charry David, Estefanía Collazos, Rojas-Sanchez Natalia, Vargas-Camacho Andrés, Rodríguez-Olarte Angel et al. · 2022 · PubMed Central
Clinical validation of an adapted Eleveld Model for high-dose propofol treatments for depression
Carter Lybbert, J. Huang, Keith G. Jones, Brian J. Mickey, Scott C. Tadler, David H. Odell, Jordan W. Stanford, Kai Kück · 2023 · Journal of Clinical Monitoring and Computing
Understanding the mechanisms of treatment response in depression, focus on electro-convulsive therapy
Elisabeth B. Binder · 2020 · European Archives of Psychiatry and Clinical Neuroscience
Transdiagnostic Symptom Subtypes to Predict Response to Therapeutic Transcranial Magnetic Stimulation in Major Depressive Disorder and Posttraumatic Stress Disorder
Camila Souza Alves Cosmo, Yosef A. Berlow, Katherine A. Grisanzio, Scott L. Fleming, Abdullah P. Rashed Ahmed, McKenna C. Brennan, Linda L. Carpenter, Noah S. Philip · 2022 · Journal of Personalized Medicine
Prediction of individual treatment allocation between electroconvulsive therapy or ketamine using the Personalized Advantage Index
Benjamin Wade, Ryan Pindale, James Luccarelli, Shuang Li, Robert C. Meisner, Stephen J. Seiner, Joan Albert Camprodon, Michael Henry · 2025 · npj Digital Medicine
Vagus nerve stimulation allows to cease maintenance electroconvulsive therapy in treatment-resistant depression: a retrospective monocentric case series
Oumaima Aboubakr, Philippe Domenech, Isabelle Heurtebise, Raphaël Gaillard, Aurore Guy-Rubin, Romain Carron, Philibert Duriez, Philip A. P. M. Gorwood, Fabien Vinckier, Johan Pallud et al. · 2024 · Frontiers in Psychiatry
Role of adjunctive cariprazine for treatment-resistant depression in patients with major depressive disorder: A systematic review and meta-analysis of randomized controlled trials
Eman Ali, Fakhar Latif, Yusra Mashkoor, Ayesha Sheikh, Amna Iqbal, Rabia Owais, Jawad Ahmed, Sadiq Naveed, Abdul Moeed, Irfan Ullah et al. · 2024 · Asian Journal of Psychiatry
Insights for the Next Generation of Ketamine for the Treatment of Depressive Disorder
Allana Cristina Faustino Martins, Bretton Badenoch, Roberto da Silva Gomes · 2025 · Journal of Medicinal Chemistry
Transcranial Magnetic Stimulation in Pregnancy: Efficacy, Safety, and Future Implications for Perinatal Mental Health Care
Serena Angeline, Babangida Tiyatiye, Wọlé Akóṣílè · 2025 · Brain and Behavior
Antidepressant- and anxiolytic-like effects of linezolid in streptozotocin-induced diabetic mice via modulation of brain serotonin and plasma corticosterone activity
Chandan K. Marathe, Vaishnavi G. Thorat, Ishwar Purushottam Kokate, Anil Tukaram Pawar, Shvetank Bhatt · 2025 · Biochemical and Biophysical Research Communications
Moderators of antidepressant augmentation versus switch in the OPTIMUM randomised controlled trial
Helena Kyunghee Kim, Jordan F. Karp, Helen Lavretsky, Daniel M. Blumberger, Patrick J. Brown, Alastair J. Flint, Emily M. Lenard, J. Philip Miller, Charles F. Reynolds, Steven P. Roose et al. · 2025 · The British Journal of Psychiatry
A randomized, double-blind, placebo-controlled, Phase 1 study to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of an immediate-release oral ketamine capsule in healthy volunteers
Mutahira M. Qureshi, Daniel Silman, Romayne Gadelrab, Hans‐Christian Stein, Pietro Carmellini, Graeme Duncan, Mitul Ashok Mehta, Allan Hunter Young, Carmel Reilly, Mário F. Juruena · 2025 · Journal of Psychopharmacology
Long-term treatment with esketamine nasal spray in patients with treatment resistant depression: Results from the ESCAPE-LTE study
Andreas Reif, Yağcıoğlu AE Anıl, István Bitter, Jozefien Buyze, R Frey, Fu DJ, Yordan Godinov, L Haggström, Yerkebulan Kambarov, RE Nielsen et al. · 2026 · European Neuropsychopharmacology
A phase 2 uncontrolled, open-label study of intranasal BPL-003 (5-methoxy- N,N -dimethyltryptamine) in patients with treatment-resistant depression
Claire Roberts, Mathieu Seynaeve, Anna O. Ermakova, Fiona Dunbar, Hattie Wells, Adeep Puri, Catherine Bird, James Rucker · 2026 · Journal of Psychopharmacology
Prevalence and factors associated with polypharmacy among patients treated for psychiatric disorders in Palestine
Suhaib Hattab, Naim Kittana, Layth Qasarweh, Malek Ahmaro, Yazid Atatre, Yasin Tayem · 2023 · Palestinian medical and pharmaceutical journal/Palestinian medical & pharmaceutical journal
Differences in Clinical Presentations of Patients Seeking Care for Treatment-Resistant Depression across Sexual Orientations and Gender Identities
Isabel Benjamin, Rachel Hershenberg, Kate D. Dorrell, Amanda C. Tan, Patricio Riva‐Posse, William Maffitt McDonald, Adriana Patricia Hermida, Andrea L. Crowell, Brian A. Feinstein · 2023 · Annals of Clinical Psychiatry
Real-world case series of maintenance theta burst stimulation therapy following response to acute theta burst stimulation therapy for difficult-to-treat depression
Yoshihiro Noda, Kyoshiro Fujii, Shinichiro Nakajima, Ryosuke Kitahata · 2024 · CNS Spectrums
Brain RFamide Neuropeptides in Stress-Related Psychopathologies
Anita Kovács, Evelin Szabó, Kristóf László, Erika Kertes, Olga Zagorácz, Kitti Mintál, Attila Tóth, Rita Gálosi, Beáta Berta, László Lénárd et al. · 2024 · Cells
Comparison of overall survival and healthcare resource utilization among patients with major depressive disorder with or without psychiatric emergency admission: A real-world study from Hungary
Zoltán Rihmer, Péter Döme, György Szekeres, László Fehér, Péter Kunovszki, Judit Gimesi-Országh, Qian Cai, Antoine C. El Khoury, István Bitter · 2024 · Journal of Affective Disorders
MicroRNA Expression Profile Is Altered by Short-Term and Chronic Lithium Treatment in a Rat Model of Depression
Maria Kachel, Antonina Dola, Mikołaj Kubiak, Wendy Majewska, Joanna Nowakowska, Wojciech Langwiński, Szymon Hryhorowicz, Aleksandra Szczepankiewicz · 2024 · Journal of Molecular Neuroscience
Impact of repetitive transcranial magnetic stimulation on clinical and cognitive outcomes, and brain-derived neurotrophic factor levels in treatment-resistant depression
Enrico Ginelli, Lucia Sanna, Pasquale Paribello, Ulker Isayeva, Giorgio Corona, Clement C.H. Zai, Daniela Manca, Maria Novella Iaselli, Roberto Collu, Federica Pinna et al. · 2025 · Frontiers in Psychiatry
Fixed dose combination dextromethorphan-bupropion: A hope for treatment resistant depression (TRD)
Ranjan Das, Rajarshi Chakravarty, Varaha Venkat Gantait, Subir Bhattacharjee · 2025 · Indian Journal of Psychiatry
Anticonvulsants: The Psychotropic and Medically Protective Drugs of the Future
Michael Raymond Binder · 2021 · American Journal of Clinical and Experimental Medicine
ICEBERG study: an indirect adjusted comparison estimating the long-term benefit of esketamine nasal spray when compared with routine treatment of treatment resistant depression in general psychiatry
Albino Jorge Oliveira-Maia, Joachim Morrens, Benoît Rive, Yordan Godinov, Jedelyn Cabrieto, Nolen Joy Perualila, S. Barbreau, Siobhán Mulhern-Haughey · 2023 · Frontiers in Psychiatry
A Retrospective Case–Control Study on the Differences in the Effectiveness of Theta-Burst Stimulation Therapy for Depression with and without Antidepressant Medication
Haruki Ikawa, Yuya Takeda, Ryota Osawa, Akiko Sato, Hoshimi Mizuno, Yoshihiro Noda · 2024 · Journal of Clinical Medicine
Brain stimulation poised to move from last resort to frontline treatment
Philip Yam · 2024 · Proceedings of the National Academy of Sciences
Comparing the Neurocognitive Effects of Right Unilateral Ultra-Brief Pulse Electroconvulsive Therapy and Magnetic Seizure Therapy for the Treatment of Major Depressive Episode
Shawn M. McClintock, Zhi‐De Deng, Mustafa M. Husain, Vishal J Thakkar, Elisabeth R. Bernhardt, Richard D. Weiner, Bruce M. Luber, Sarah Hollingsworth Lisanby · 2024 · Biological Psychiatry Cognitive Neuroscience and Neuroimaging
A Retrospective Analysis of the Impact of Electroconvulsive Therapy on Anxiety Symptoms in Patients With Treatment-Resistant Depression
Julia Laszcz, Chenyang Wang, Patricio Riva‐Posse, Jonathan Kim, Valeriya Tsygankova, Ally Mandell, Hanna Rice, Adriana Patricia Hermida, Brandon M. Kitay, Andrea L. Crowell et al. · 2025 · Journal of Ect
Differential impact of extracts from distinct Sceletium tortuosum chemotypes on central neurotransmitter concentrations in C57BL/6 mice
Catherine H. Kaschula, Anna‐Mart Engelbrecht, Nokwanda Pearl Makunga, Magriet Muller, André J. de Villiers, Kamano Mochoele Dube, Sarel Jacobus Brand, Jo-Anne Stroebel, Willem A. L. van Otterlo, De Wet Wolmarans · 2025 · Journal of Ethnopharmacology
Digital health monitoring for adults with treatment-resistant depression: Observational feasibility study protocol
Karisa B. Parkington, Reinhard Janssen‐Aguilar, Gyu Hee Lee, Alice Rueda, Fathima Adamsahib, Mohammad Al-Hassan, Stephanie Famuditimi, Perry J. C. Menzies, Qiaowei Lin, Wendy Y. W. Lou et al. · 2025 · PLoS ONE
Efficacy and safety of transcranial direct current stimulation (tDCS) on treatment-resistant depression (TRD): A systematic review and Meta-analysis of randomized clinical trials
Reza Moshfeghinia, Ramtin Naderian, Amirhossein Najibi, Hoorad Mohagheghzadeh, Kiarash Kavari, Saghar Elmi, Armina Torabian, Sanaz Parizan, Saeed Abdollahifard, Konstantin V. Slavin et al. · 2026 · Journal of Affective Disorders
Balancing Evidence and Need: Variation in US Commercial Payer Coverage of Esketamine
Ekwu B. Ochigbo, Molly T. Beinfeld, James D. Chambers · 2024 · Clinical Therapeutics
Real-world demographic and clinical profiles of patients with treatment-resistant depression initiated on esketamine nasal spray
Ludovic Samalin, Lila Mékaoui, Pierre de Maricourt, Anne Sauvaget, M.A. Codet, E. Gaudre-Wattinne, Clotilde Wicart, Maud Rothärmel · 2024 · International Journal of Psychiatry in Clinical Practice
Estimating the benefit of esketamine nasal spray versus real-world treatment on patient-reported functional remission: results from the ICEBERG study
Albino Jorge Oliveira-Maia, Benoît Rive, Yordan Godinov, Siobhán Mulhern-Haughey · 2024 · Frontiers in Psychiatry
Treatment-resistant depression
Leesa A. McBroom, Melissa Timmons · 2024 · The Nurse Practitioner
High-dose Versus Low-dose Oral Ketamine on Control and Relapse of Treatment-resistant Depression: A Randomized, Double-blinded Clinical Trial
Gholamreza Kheirabadi, Shirin Golkar · 2023 · Iranian Journal of Psychiatry and Behavioral Sciences
Opportunities and challenges for the use of deep brain stimulation in the treatment of refractory major depression
Prashin Unadkat, João Quevedo, Jair C. Soares, Albert J. Fenoy · 2024 · Discover Mental Health
A scoping review of the effects of mushroom and fungus extracts in rodent models of depression and tests of antidepressant activity
Catherine K. Wang, Gio Kim, Lily R. Aleksandrova, William J. Panenka, Alasdair M. Barr · 2024 · Frontiers in Pharmacology
Brain-based correlates of depression and traumatic brain injury: a systematic review of structural and functional magnetic resonance imaging studies
Vanessa A. Baltazar, Ilya Demchenko, Vanessa K. Tassone, Rachel L. Sousa-Ho, Tom A. Schweizer, Venkat Bhat · 2024 · Frontiers in Neuroimaging
Recognition and management of treatment-resistant depression
Cyrus Ma, Brittany Strelow · 2024 · JAAPA
Innovative Therapeutic Approaches in Severe Adolescent Depression: Neuroimaging and Pharmacological Insights
Andrei-Gabriel Zanfir, Simona Corina Trifu · 2025 · Balneo and PRM Research Journal
A case of treatment-resistant depression in an older adult and a discussion of treatment options
Emma Pope, Sabarigirivasan Muthukrishnan, James Phillips, Sarah M. Phillips · 2021 · BJPsych Bulletin
Unraveling the Mysteries of Mental Illness With Psilocybin
Robert Sottile, Herpreet Singh, Anne Weisman, Thomas Vida · 2022 · Cureus
Ultrasound applications in the treatment of major depressive disorder (MDD): A systematic review of techniques and therapeutic potentials in clinical trials and animal model studies
Gansheng Tan, Hong Chen, Eric C Leuthardt · 2025 · medRxiv
The effects of chronic desipramine treatment on neurotrophin-3 in the brain of mice with selective depletion of CREB and CREM in noradrenergic neurons
Katarzyna Rafa–Zabłocka, Irena Nalepa, Grzegorz Kreiner · 2024 · Neuroscience
Patient experiences of treatment-resistant depression (TRD): A systematic review and qualitative meta-synthesis
Alexandra Cernat, Manisha Pahwa, Dima Hadid, Katrina Shen, Julia Abelson, Zainab Samaan, Amanda Ramdyal, Meredith G. Vanstone · 2024 · PLOS mental health.
Investigating the effects of group dance movement therapy sessions in adults living with treatment resistant depression: A mixed method case series
Neha Christopher, Jeanette Tamplin, Ella Dumaresq, Sherry W. Goodill · 2025 · The Arts in Psychotherapy
Comparative Efficacy and Functional Outcomes of Psychedelic-Assisted Therapies in Treatment-Resistant Depression: A Systematic Review of Recent Clinical Trials
Ciara S Mimms, Kassandra Sotelo, Abdul Khaliq · 2025 · Cureus
Intravenous Ketamine Treatment for Depression: One-year Retrospective Study from a Tertiary Care Psychiatry Center from India
Ekta Yadav, Bheemsain V. Tekkalaki, Kavita P. Gadadavar, Vishwas Shrishail Yadawad, Sameeran S. Chate, Sandeep Patil, Vinayak Koparde · 2025 · Indian Journal of Psychological Medicine
Effectiveness of fMRI-based Neurofeedback Therapy on Depression: A Systematic Review
Ali Khaleghi, Hannaneh Samiei, Hadi Zarafshan, Shahab Alaedin Baloochi, Mohammad Reza Mohammadi · 2025 · Clinical Psychopharmacology and Neuroscience
Anxiolytic and Antidepressant Effects of Organic Polysulfide, Dimethyl Trisulfide Are Partly Mediated by the Transient Receptor Potential Ankyrin 1 Ion Channel in Mice
Kitti Göntér, Viktória Kormos, Erika Pintér, Gábor Pozsgai · 2025 · Pharmaceutics
Acupressure as a non-pharmacological treatment for depression: Neurophysiological, biochemical, and psychological mechanisms
Cong-Ya Chen, Yi Zhang · 2025 · Journal of Psychiatric Research
Ultrasound Applications in the Treatment of Major Depressive Disorder: A Systematic Review of Techniques and Therapeutic Potentials in Clinical Trials and Animal Model Studies
Gansheng Tan, Hong Chen, Eric C Leuthardt · 2025 · Neuromodulation Technology at the Neural Interface
Real-world analysis of pharmacological treatments to prevent relapse after electroconvulsive therapy for major depressive disorder: A nationwide cohort study
Alexander Kronsell, Axel Nordenskjöld, Robert Bodén, Ellenor Mittendorfer‐Rutz, Johan Reutfors, Marios Rossides, Mikael Tiger · 2025 · Translational Psychiatry
From symptoms to systems: A comprehensive review of the clinical utility of classic and novel approaches to major depression subtyping
Charles W. Beckett, Rebecca P Lawson · 2025 · Journal of Affective Disorders
A Prognostic Theory of Treatment Response for Major Depressive Disorder: A Dynamic Systems Framework for Forecasting Clinical Trajectories
Harold Ngabo-Woods, Larisa Dunai, Isabel Seguí Verdú · 2025 · Applied Sciences
From the gut to the brain: Potential novel avenues for IBD treatment via serotonergic pathways
Sara Ibgui, Daisy Lints, Simon W. F. Milling · 2025 · Pharmacological Research
Accelerated intermittent theta burst stimulation effectively and rapidly reduces suicidal ideation in depression patients: A randomized, sham-controlled study
Lifen Chen, Wei-Chou Chang, Chi-Hsiang Chung, Alexander Thomas Sack, Ching‐En Lin, Hsin-An Chang · 2025 · Psychiatry Research
A Multimodal Framework for Prognostic Modelling of Mental Health Treatment and Recovery Trajectories
Harold Ngabo-Woods, Larisa Dunai, Isabel Seguí Verdú, Liang Sui · 2026 · Applied Sciences
Distinct and common subcortical functional connectivity revealed across three major psychiatric disorders
Wan-Chen Chang, Duan‐Pei Hung, Mu‐Hong Chen, Tung‐Ping Su, Ya‐Mei Bai, You-Yin Chen, Pei‐Chi Tu · 2026 · Psychological Medicine
Advances in non-pharmacological therapies for depressive disorders: A systematic review
Hong Liu, Jiazhen Cai, Lei Mao, Boyang Dai, Yansong Wang, Yue Gao, Qiuyu Gu, Yifei Liu, Ran Jing, Xin Zhou et al. · 2026 · Brain Behavior and Immunity Integrative
Sustaining the benefits of intravenous ketamine with behavioural activation therapy for depression: A case series
Jennifer Lynne Phillips, Pierre Blier, Jeanne D. Talbot · 2023 · Journal of Affective Disorders Reports
Pharmacological treatment of treatment-resistant depression: Towards evidence-based recommendations
Stefan Jerotić, Maja Ivković · 2024 · Medicinska istrazivanja
Response to Intermittent Theta Burst Stimulation in Treatment-Resistant Depression
Mustafa Tonkul, Bernhard Theodor Baune, Erhan Kavakbasi · 2024 · Journal of Ect
Understanding profiles of patients with treatment-resistant depression by stringency of health plan prior authorization criteria for approval of esketamine nasal spray
Lisa Harding, Maryia Zhdanava, Aditi Shah, Jacqueline A. Pesa, Todor I. Totev, Anabelle Tardif‐Samson, Dominic Pilon, Kruti Joshi · 2024 · Current Medical Research and Opinion
Case report: Personalizing the use of trazodone in real-world patients: a study of three cases of depression with comorbidities
Gianluca Rosso, Beatrice Benatti, Mauro Pettorruso, Gaia Sampogna, Carmine Tomasetti · 2024 · Frontiers in Psychiatry
Research hotspots and trends in transcranial magnetic stimulation for cognitive impairment: A bibliometric analysis from 2014 to 2023
Qi Zhang, Peng-Peng Zhu, Lun Yang, Aisong Guo · 2024 · World Journal of Psychiatry
Predictors of dropout from TMS for treatment resistant depression
Robert Hickson, Kayla Huynh, Linden B. Aly, Jerome Albert Yesavage, Noah S. Philip, Frank Andrew Kozel, Michelle R. Madore · 2025 · Transcranial magnetic stimulation .
A computational account of joint SSRI and anti-inflammatory treatment
Melissa Reneaux, Helen S. Mayberg, Karl John Friston, Dimitris A. Pinotsis · 2025 · Frontiers in Immunology
Knowledge and attitudes about the use of psychedelic drugs among psychiatric professionals in Korea
Won-Seok Choi, Jeongwan Hong, Seung-Ho Jang, Jung Goo Lee, InKi Sohn, François Lilienthal, Jeong Seok Seo, Nak-Young Kim, Og-Jin Jang, Duk‐In Jon · 2025 · Journal of Psychedelic Studies
Amygdala subregional functional connectivity in treatment-resistant depression
Sheryl Foster, Ramón Landín-Romero, Sarah Jayne Lewis, Ana Rita Barreiros, Sophie Matis, Anthony W.F. Harris, Mayuresh S. Korgaonkar · 2025 · Journal of Affective Disorders Reports
Precision medicine in psychiatry: Case series on pharmacogenomic solutions for treatment-resistant depression
Gryan Garcia, Christy Cotner, Robert Spano · 2025 · Journal of the American Association of Nurse Practitioners