Untreated depression in the first trimester of pregnancy leads to postpartum depression: high rates from a natural follow-up study
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BACKGROUND: This is a natural follow-up study that presents the postpartum results of women who experienced depression during pregnancy. METHODS: This study involved 78 women diagnosed with depression in the first trimester of pregnancy. All patients were diagnosed using the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) in the first trimester and all were referred to a psychiatric center for treatment. Of the 78, 73 were contacted postpartum and reassessed by SCID-I. Treatment anamnesis was evaluated retrospectively. RESULTS: The women were divided into two groups at the postpartum evaluation according to anamnesis of psychiatric treatment. Twenty-one of the 73 (28.7%) had received treatment during pregnancy (treated group). Fifty-two women had not been treated (untreated group). In the treated group, no postpartum depression was determined (0%). In the untreated group, 92% (n=48) of women had a depressive disorder postpartum (P<0.01). In addition, scores regarding depression, functionality, and perceived social support were worse postpartum for the untreated group. CONCLUSION: Untreated depression during pregnancy is an important predictor of postpartum depression. This natural follow-up study is important because it presents very striking rates of postpartum depression. Referral of patients with depression during pregnancy to psychiatric treatment should be provided and is strongly encouraged.
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Untreated depression during pregnancy is an important predictor for postpartum depression.
“However, untreated depression during pregnancy is an important predictor for postpartum depression.74”
From Effects of bright light therapy for depression during pregnancy: a randomised, double-blind controlled trial (2020) · cites this paper as [74]
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References 30 · Cited by 67
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- Authors
- Yazici, E., Kirkan, T. S., Akcali aslan, P., Aydın, N., & Yazici, A. B.
- Affiliations
- Bakırköy Psychiatric Hospital (TR)
- ORCID
- Aydın, Nazan
- Venue
- Neuropsychiatric Disease and Treatment
- Publisher
- Informa UK Limited
- Published
- 2015-02
- Volume
- 11
- Pages
- 405
- ISSN
- 1176-6328 (ISSN-L)
- 1178-2021
- PMC
- PMC4344179
- OpenAlex
- W2103756535
- Cited by
- 67
- References
- 30
- Citations by year
- 2026: 6 · 2025: 6 · 2024: 3 · 2023: 18 · 2021: 4 · 2020: 6 · 2019: 2 · 2018: 7 · 2017: 8 · 2016: 5 · 2015: 2
- FWCI
- 7.86
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Neuropsychiatric Disease and Treatment (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Sakarya Üniversitesi Kurumsal Açık Akademik Arşivi (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Dove Medical Press (Taylor and Francis Group) (submittedVersion, cc-by-nc)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy-related medical research
- Keywords
- postpartum depression, antenatal depression, first trimester, untreated depression, social support, functional disability
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