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Cited by 18Poisoning and overdose treatmentsForensic Toxicology and Drug AnalysisHistorical and Scientific Studies

A Three-Year Study on Acute Poisoning Cases Brought for Medico-Legal Autopsy in a North-Eastern City of India

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Goswami, Oli, Mahanta, Putul, Kalita, Deepjyoti, Konwar, Ranjumoni, Yadav, Dhirendra Singh·2021·Open Access Emergency Medicine
DOI 10.2147/oaem.s297083PMC PMC7886380
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Abstract

Purpose: Death due to acute poisoning is one of the significant health challenges to cope-up. It is imperative to know the death victims’ pattern due to acute poisoning to prepare the relevant preventive and remedial measures. Therefore, the present study aimed to assess the pattern of the dead victims of acute poisoning in a tertiary care centre. Materials and Methods: It is a hospital record-based study and conducted in a tertiary care centre. Descriptive statistics to study the distribution of the cases among different age groups, sex, type of poison compounds was computed and analysed using SPSS software version 20. Results: The present study detected poisonous substances in 244 (41.8%) cases out of 584 death cases of suspected acute poisoning with the male preponderance of 62.29%. A higher incidence of acute poisoning was noticed among the young age group 21– 30 years (33.6%) with 48 (31.6%) cases among males and 34 (36.9%) cases of the female. The Organophosphates (OP) was the main compound found in 151 (61.9%) fatal cases, followed by Carbamate in 45 (18.4%) cases. We also observed a maximum, 76 (36.2%) cases of suicidal victims in the age group of 21– 30 years. Children and lower age group were more vulnerable to accidental poisoning as 26.5% cases of accidental death were reported in both the age group of 0– 10 and 11– 20 years respectively, gradually declining and practically found nil in above 60 years group. These differences of frequencies were found statistically significant (p < 0.0001), χ 2 = 55.1. Conclusion: The results suggest due consideration to the young adolescents’ groups without any sexual discrimination to define guidelines for appropriate handling, storage and transportation of the poisonous compounds. Organophosphate’s involvement as the most preferred agent in acute poisoning is to be remembered to help manage poisoning cases. Keywords: organophosphates, socio-demographic variation, nature of poisoning, agriculture poisoning

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  • In India, the most frequently found substances in toxicological analyses were organophosphates (61.9%), followed by carbamates (18.4%) and other organic derivatives.

    “The most frequently found substance in toxicological analyses, carried out using GC-SM methods, were organophosphates (pesticides, 61.9%), followed by insecticides such as carbamates (18.4%) and other organic derivatives.”

    From Toxicological Findings of Self-Poisoning Suicidal Deaths: A Systematic Review by Countries (2022) · cites this paper as [20]

    The Results (Table 2) report organophosphates in 61.9% of detected poisoning cases and carbamates in 18.4%; Materials and Methods says GC-MS was used for confirmation. These figures come from medico-legal autopsies in one north-eastern Indian city, not toxicological analyses across India. Table 2 lists the remaining substances individually rather than grouping them all as “other organic derivatives.” (LLM, conf=0.86)

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  • In India, Goswami et al. found that of 584 suspected poisoning deaths, 41.8% were poisoning and 86% of those were suicides.

    “The retrospective study by Goswami et al. [20] examined autopsies of suspected deaths by poisoning. Of the 584 cases, 41.8% (244) were of poisoning, of which, 86% (210) were cases of suicide.”

    From Toxicological Findings of Self-Poisoning Suicidal Deaths: A Systematic Review by Countries (2022) · cites this paper as [20]

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Research works printed but not linked: 24

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Authors
Goswami, O., Mahanta, P., Kalita, D., Konwar, R., & Yadav, D. S.
Affiliations
  • Gauhati Medical College and Hospital (IN)
  • Assam Medical College (IN)
  • All India Institute of Medical Sciences Rishikesh (IN)
  • Central Forensic Science Laboratory (IN)
Corresponding author
Mahanta, Putul
ORCID
Venue
Open Access Emergency Medicine
Publisher
Informa UK Limited
Published
2021-02
Volume
Volume 13
Pages
45-50
ISSN
1179-1500 (ISSN-L)
DOI
10.2147/oaem.s297083
PMC
PMC7886380
OpenAlex
W3126848621
Cited by
18
References
1
Citations by year
2026: 2 · 2025: 3 · 2024: 1 · 2023: 7 · 2022: 5
FWCI
3.40
Type
journal article
Language
en
Open access
Licence
Locations
  • Open Access Emergency Medicine (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Emergency Medicine › Poisoning and overdose treatments
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Forensic Toxicology and Drug Analysis
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Historical and Scientific Studies
Keywords
acute poisoning, poisoning deaths, organophosphates, carbamates, suicide, socio-demographic patterns, forensic autopsy, poisoning prevention

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