Metabolite Fingerprinting and Profiling of the Medicinal Grass Eleusine indica Based on HPLC-DAD, UPLC-DAD-MS/MS and NMR Analyses
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Aqueous preparations of the grass Eleusine indica are used for treating malaria and lung infections.Despite its widespread occurrence and therapeutic potential, little is known about its chemical composition.This study reports a common chemical pattern for aqueous extracts of E. indica samples from four different localities, separated from each other by approximately 75 to 1340 km, in a wide variety of abiotic and biotic factors.High-performance liquid chromatography with diode array detection (HPLC-DAD), ultra-performance liquid chromatography with diode array detection and mass spectrometry (UPLC-DAD-MS/MS), and nuclear magnetic resonance (NMR) were the analytical techniques applied to characterize substances from E. indica, from each locality.Principal component analysis (PCA) confirmed that E. indica specimens came from four different localities.However, all of the four populations showed a common peaks pattern.This is the first chemical profile report of E. indica.Moreover, p-coumaric acid and isoschaftoside were characterized for the first time in this species.
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A recent metabolite fingerprinting and profiling on E. indica extract characterized p-coumaric acid and isoschaftoside along with a series of primary metabolites and amino acids.
“A recent metabolite fingerprinting and profiling on the plant extract has characterized two more phytochemicals known as p -coumaric acid and isoschaftoside along with a series of primary metabolites and amino acids (Peñaloza et al. 2018).”
From Eleusine Indica for Food and Medicine (2021) · cites this paper as Peñaloza et al. 2018
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Adoho, A. C. C., Zinsou, F. T., Olounlade, P. A., Azando, E. V. B., Hounzangbe-Adote, M. S., & Gbangboche, A. B. (2021) · Journal of Pharmacognosy and Phytochemistry · doi:10.22271/phyto.2021.v10.i3a.14060 · Cited by 19 · see citing works
“Aerial parts Lyophilized extract acid p-coumarique [26]”
BackgroundInfluentialEleusine Indica for Food and Medicine
Zakri, Z. H. M., Suleiman, M., Ng, S. Y., Ngaini, Z., Maili, S., & Salim, F. (2021) · Journal of Agrobiotechnology · doi:10.37231/jab.2021.12.2.260 · Cited by 10 · see citing works
(2021) · Acta Medica Philippina · doi:10.47895/amp.vi0.3262 · Cited by 1 · see citing works
- Authors
- Peñaloza, E., Casanova, L., Leal, I., de Aguiar, P., & Costa, S.
- Affiliations
- Universidade Federal do Rio de Janeiro (BR)
- Corresponding author
- Costa, Sônia
- Venue
- Journal of the Brazilian Chemical Society
- Published
- 2018
- ISSN
- 0103-5053 (ISSN-L)
- 1678-4790
- OpenAlex
- W2868568121
- Cited by
- 14
- References
- 0
- Citations by year
- 2024: 2 · 2023: 1 · 2022: 5 · 2021: 6
- FWCI
- 1.33
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- other-oa
- Locations
- Journal of the Brazilian Chemical Society (publishedVersion, other-oa)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
- Americanae (AECID Library) (submittedVersion, cc-by)
- Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Universidade Federal do Rio de Janeiro
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry Medicinal Plant Applications
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant chemical constituents analysis
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
- Keywords
- Eleusine indica, metabolic fingerprinting, chemical profiling, medicinal grass, aqueous plant extract, p-coumaric acid, isoschaftoside, phytochemicals, regional variation, malaria treatment
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