Clinical Significance of the Cytochrome P450 2C19 Genetic Polymorphism
Desta, Zeruesenay, Zhao, Xiaojiong, Shin, Jae-Gook, Flockhart, David A.·2002·Clinical Pharmacokinetics
Cites (358)
Items 201–358 of 358
- Efficacy of triple therapy with rabeprazole for Helicobacter pylori infection and CYP2C19 genetic polymorphismK Hokari, Toshiro Sugiyama, Mototsugu Kato et al. · 2001 · Alimentary Pharmacology & Therapeutics
- Genetic polymorphism of (S)‐mephenytoin 4′‐hydroxylation in populations of African descentXie, Kim, Stein, Wilkinson, Wood · 1999 · British Journal of Clinical Pharmacology
- Effects of felbamate on the pharmacokinetics of phenobarbitalPascale Reidenberg, Paul Glue, Christopher R. Banfield et al. · 1995 · Clinical Pharmacology & Therapeutics
- Meta-analysis of phenotype and genotype of NAT2 deficiency in Chinese populationsHong‐Guang Xie, Zhenhua Xu, Dongsheng Ouyang · 1997 · Pharmacogenetics
- High frequencies of CYP2C19 mutations and poor metabolism of proguanil in VanuatuAkira Kaneko, Osamu Kaneko, George K. Taleo, Anders Björkman, Takatoshi Kobayakawa · 1997 · The Lancet
- Fluvoxamine inhibits the CYP2C19-catalyzed bioactivation of chloroguanide*U. Jeppesen, Birgitte Buur Rasmussen, Kim Brøsen · 1997 · Clinical Pharmacology & Therapeutics
- Lack of low Km diazepam N-demethylase in livers of poor metabolizers for S-mephenytoin 4'-hydroxylationToshio Yasumori, Qinghua Li, Yasushi Yamazoe · 1994 · Pharmacogenetics
- Diazepam metabolism in native Chinese poor and extensive hydroxylators of S-mephenytoin: Interethnic differences in comparison with white subjectsYuan Zhang, Jesús Reviriego, Ya‐Qing Lou · 1990 · Clinical Pharmacology & Therapeutics
- Plasma levels of the enantiomers of thioridazine, thioridazine 2-sulfoxide, thioridazine 2-sulfone, and thioridazine 5-sulfoxide in poor and extensive metabolizers of dextromethorphan and mephenytoin*Chin B. Eap, Theodor W. Guentert, Martina Schäublin-Loidl · 1996 · Clinical Pharmacology & Therapeutics
- Extent of Urinary Excretion of p-Hydroxyphenytoin in Healthy Subjects Given PhenytoinRONALD G. DICKINSON, Wayne D Hooper, Marc C. Patterson · 1985 · Therapeutic Drug Monitoring
- Polymorphism in hydroxylation of mephenytoin and hexobarbital stereoisomers in relation to hepatic P-450 human-2Toshio Yasumori, Norie Murayama, Yasushi Yamazoe · 1990 · Clinical Pharmacology & Therapeutics
- Chloroguanide metabolism in relation to the efficacy in malaria prophylaxis and the S-mephenytoin oxidation in Tanzanians*Erik Skjelbo, Theonest K. Mutabingwa, Ib Christian Bygbjerg · 1996 · Clinical Pharmacology & Therapeutics
- Role of cytochrome P450 in estradiol metabolism in vitro.Zeneng Cheng, Yan Shu, Zhaoqian Liu, Liansheng Wang, Dongsheng Ouyang, Hong-Hao Zhou · 2001 · PubMed
- Polymorphic drug metabolism.Mary V. Relling · 1989 · PubMed
- Sufficient effect of 1-week omeprazole and amoxicillin dual treatment for Helicobacter pylori eradication in cytochrome P450 2C19 poor metabolizers.Nobuo Aoyama, Yusuke Tanigawara, Tomoko Kita · 1999 · PubMed
- The induction effect of rifampicin on activity of mephenytoin 4′‐hydroxylase related to M1 mutation of CYP2C19 and gene doseHua‐Jun Feng, Song‐Lin Huang, Wei Wang, Hong‐Hao Zhou · 1998 · British Journal of Clinical Pharmacology
- Phenotypic-genotypic analysis of CYP2C19 in the Jewish Israeli populationSigal Sviri, Shoshi Shpizen, E LEITERSDORF · 1999 · Clinical Pharmacology & Therapeutics
- Genotypes for the cytochrome P450 enzymes CYP2D6 and CYP2C19 in human longevityLise Bathum, Karen Andersen‐Ranberg, Jesper L. Boldsen · 1998 · European Journal of Clinical Pharmacology
- Cytochrome P450 EnzymesAnne Tamborski Harvey, Sheldon Preskorn · 1996 · Journal of Clinical Psychopharmacology
- CYP2D6 and CYP2C19 genotypes in an elderly Swedish populationHiroshi Yamada, Marja‐Liisa Dahl, L. Lannfelt · 1998 · European Journal of Clinical Pharmacology
- Pharmacokinetics of [14C]Omeprazole in Patients with Liver CirrhosisTommy Andersson, Rolf Olsson, Carl Gunnar Regårdh · 1993 · Clinical Pharmacokinetics
- Stereoselective metabolism and disposition of the enantiomers of mephenytoin during chronic oral administration of the racemic drug in man.Adrian Kupfer, Paul V Desmond, S. Schenker · 1982 · Journal of Pharmacology and Experimental Therapeutics
- Differences between white subjects and Chinese subjects in the in vivo inhibition of cytochrome P450s 2C19, 2D6, and 3A by omeprazole*Yoseph Caraco, Grant R. Wilkinson, Alastair J. J. Wood · 1996 · Clinical Pharmacology & Therapeutics
- Determination of CYP2C19 phenotype in black Americans with omeprazole: Correlation with genotype*Jacqueline S. Marinac, John Dikran Balian, John W. Foxworth · 1996 · Clinical Pharmacology & Therapeutics
- Selective Serotonin Reuptake Inhibitors and Tricyclic Antidepressants in CombinationDavid M. Taylor · 1995 · The British Journal of Psychiatry
- Warfarin‐Fluoxetine and Diazepam‐Fluoxetine InteractionLarry A. Dent, Marv W. Orrock · 1997 · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy
- In vitro characterization of the inhibition profile of loratadine, desloratadine, and 3-OH-desloratadine for five human cytochrome P-450 enzymes.Mary E. Barecki, Christopher N. Casciano, William W. Johnson · 2001 · PubMed
- Seizures and myoclonus associated with antidepressant treatment: assessment of potential risk factors, including CYP2D6 and CYP2C19 polymorphisms, and treatment with CYP2D6 inhibitorsOlav Spigset, Karin Hedenmalm, M L Dahl · 1997 · Acta Psychiatrica Scandinavica
- Relationship of In Vitro Data on Drug Metabolism to In Vivo Pharmacokinetics and Drug InteractionsJürgen Schmider, David J. Greenblatt, Lisa Lvon Moltke · 1996 · Journal of Clinical Psychopharmacology
- Effect of the CYP2C19 oxidation polymorphism on fluoxetine metabolism in Chinese healthy subjectsZhaoqian Liu, Zeneng Cheng, Song‐Lin Huang · 2001 · British Journal of Clinical Pharmacology
- Flunitrazepam metabolism by cytochrome P450S 2C19 and 3A4.Tansel Kilicarslan, Robert L. Haining, Allan E. Rettie · 2001 · PubMed
- Pharmacokinetics of various single intravenous and oral doses of omeprazoleTB Andersson, Christer Cederberg, C. G. Reg�rdh, I. Sk�nberg · 1990 · European Journal of Clinical Pharmacology
- Interaction studies with moclobemideRobert Zimmer, Ronald Gieschke, R. Fischbach · 1990 · Acta Psychiatrica Scandinavica
- Scleroderma is associated with differences in individual routes of drug metabolism: A study with dapsone, debrisoquin, and mephenytoinDavid G. May, Carol M. Black, Nancy J. Olsen, Mary Ellen Csuka, Simpson Bobo Tanner, Lisa Bellino, James A Porter, Grant R. Wilkinson, Robert A. Branch · 1990 · Clinical Pharmacology & Therapeutics
- Steady State Plasma Levels of the Enantiomers of Trimipramine and of Its Metabolites in CYP2D6-, CYP2C19- and CYP3A4/5-Phenotyped PatientsChin B. Eap, Stefan Bender, Markus Gastpar · 2000 · Therapeutic Drug Monitoring
- Relationship between proguanil metabolic ratio and CYP2C19 genotype in a Caucasian populationJanelle M. Hoskins, Gillian M. Shenfield, Annette S. Gross · 1998 · British Journal of Clinical Pharmacology
- Lack of drug interaction between omeprazole, lansoprazole, pantoprazole and theophyllineKarin Dilger, Zhichang Zheng, Ulrich E. Klotz · 1999 · British Journal of Clinical Pharmacology
- Lack of pharmacokinetic interaction of pantoprazole with diazepam in manRoland Gugler, M. HARTMANN, J. RUDI · 1996 · British Journal of Clinical Pharmacology
- Effect of Omeprazole on the Metabolism of CilostazolAjit Suri, Steven L. Bramer · 1999 · Clinical Pharmacokinetics
- The Role of CYP2C19 in the Metabolism of (+/–) Bufuralol, the Prototypic Substrate of CYP2D6Dayna C. Mankowski · 1999 · Drug Metabolism and Disposition
- Effects of genetic defects in the CYP2C19 gene on the N‐demethylation of imipramine, and clinical outcome of imipramine therapyShigeru Morinobu, Takeshi Tanaka, Shinobu Kawakatsu, Shiro Totsuka, Eriko Koyama, KAN CHIBA, Takashi Ishizaki, Takahiro Kubota · 1997 · Psychiatry and Clinical Neurosciences
- Formation of meprobamate from carisoprodol is catalysed byCYP2C19P Dal??n, Gunnar Alván, Monique Wakelkamp · 1996 · Pharmacogenetics
- Fluvoxamine inhibits the CYP2C19-catalysed metabolism of proguanil in vitroBirgitte Buur Rasmussen, Torben Leo Nielsen, Kim Brøsen · 1998 · European Journal of Clinical Pharmacology
- Cimetidine interaction with imipramine and nortriptylineStephan A. Henauer, Leo E. Hollister · 1984 · Clinical Pharmacology & Therapeutics
- Genetic polymorphism of S-mephenytoin 4??-hydroxylation in African-AmericansTimi I. Edeki, Joyce A. Goldstein, Sonia M. F. de Morais · 1996 · Pharmacogenetics
- Ticlopidine decreases the in vivo activity of CYP2C19 as measured by omeprazole metabolismTomonori Tateishi, Toshio Kumai, Minoru Watanabe · 1999 · British Journal of Clinical Pharmacology
- Population Pharmacokinetics of Phenytoin in Japanese Patients with Epilepsy: Analysis with a Dose-Dependent Clearance Model.Atsuko ODANI, Yukiya Hashimoto, 和伸 高柳 · 1996 · Biological and Pharmaceutical Bulletin
- Pharmacokinetic Drug Interactions with Phenytoin (Part II)Roger L. Nation, Allan M. Evans, Robert W. Milne · 1990 · Clinical Pharmacokinetics
- Interaction between phenytoin and imipramine.Emilio Perucca, A. Richens · 1977 · British Journal of Clinical Pharmacology
- A Study of the Interaction Between Omeprazole and Phenytoin in Epileptic PatientsTommy Andersson, Per-Olof Lagerström, Peter Unge · 1990 · Therapeutic Drug Monitoring
- Canadian Native Indians exhibit unique CYP2A6 and CYP2C19 mutant allele frequencies*Maciej P. Nowak, Edward M. Sellers, Rachel Fynvola Tyndale · 1998 · Clinical Pharmacology & Therapeutics
- Intrinsic Efficacy of Proguanil against Falciparum and Vivax Malaria Independent of the Metabolite CycloguanilAkira Kaneko, Yngve Bergqvist, Miho Takechi, Morris Kalkoa, Osamu Kaneko, Takatoshi Kobayakawa, Takashi Ishizaki, Anders Björkman · 1999 · The Journal of Infectious Diseases
- Cobalamin deficiency with megaloblastic anaemia in one patient under long‐term omeprazole therapyAbdelouahab Bellou, Isabelle Aimone‐Gastin, Jean-Dominique de Korwin, Jean–Pierre Bronowicki, Anne Moneret-Vautrin, J. P. Nicolas, Marc‐André Bigard, Jean‐Louis Guéant · 1996 · Journal of Internal Medicine
- Genetic polymorphism of debrisoquine (CYP2D6) and proguanil (CYP2C19) in South Pacific Polynesian populationsSompon Wanwimolruk, S. Bhawan, Peter F. Coville, S. C. W. Chalcroft · 1998 · European Journal of Clinical Pharmacology
- Human CYP2C-mediated stereoselective phenytoin hydroxylation in Japanese: difference in chiral preference of CYP2C9 and CYP2C19Toshio Yasumori, Laishun Chen, Qinghua Li · 1999 · Biochemical Pharmacology
- Steady-State Plasma Concentrations of Imipramine and Desipramine in Relation to S-Mephenytoin 4'-Hydroxylation Status in Japanese Depressive PatientsEriko Koyama, Takeshi Tanaka, Kan Chiba · 1996 · Journal of Clinical Psychopharmacology
- Evidence for the effect of gender on activity of (S)-mephenytoin 4???-hydroxylase (CYP2C19) in a Chinese populationZhenhua Xu, Song‐Lin Huang, Zhousheng Xiao · 1997 · Pharmacogenetics
- Metabolic disposition of imipramine in oriental subjects: relation to metoprolol alpha-hydroxylation and S-mephenytoin 4'-hydroxylation phenotypes.Eriko Koyama, Dong‐Ryul Sohn, S. G. Shin · 1994 · Journal of Pharmacology and Experimental Therapeutics
- Mephenytoin and sparteine pharmacogenetics in Canadian CaucasiansT. Inaba, M Jurima, Masayuki Nakano · 1984 · Clinical Pharmacology & Therapeutics
- Are the orally administered proton pump inhibitors equivalent? A comparison of lansoprazole, omeprazole, pantoprazole, and rabeprazoleAlan B.R. Thomson · 2000 · Current Gastroenterology Reports
- Stereoselective disposition of hexobarbital and its metabolitesAdedayo B. Adedoyin, C. Prakash, D. O??Shea · 1994 · Pharmacogenetics
- Cure of refractory duodenal ulcer and infection caused by Helicobacter pylori by high doses of omeprazole and amoxicillin in a homozygous CYP2C19 extensive metabolizer patientTakahisa Furuta · 2000 · Clinical Pharmacology & Therapeutics
- The role of S‐mephenytoin hydroxylase (CYP2C19) in the metabolism of the antimalarial biguanides.JD Wright, Nuala Ann Helsby, Stephen Andrew Ward · 1995 · British Journal of Clinical Pharmacology
- Genotype analysis of the CYP2C19 gene in the Japanese populationYutaka Tsuneoka, Kouji Fukushima, Yoshinori Matsuo · 1996 · Life Sciences
- Effect of CYP2C19 polymorphism on serum levels of vitamin B12 in patients on long‐term omeprazole treatmentSAGAR, JANCZEWSKA, �. Ljungdahl, Bertilsson, SEENSALU · 1999 · Alimentary Pharmacology & Therapeutics
- Fatality Associated With Combined Fluoxetine-Amitriptyline TherapyBryan Baker · 1997 · JAMA
- Proguanil metabolism is determined by the mephenytoin oxidation polymorphism in Vietnamese living in Denmark.Kim Brøsen, Erik Skjelbo, Helga Flachs · 1993 · British Journal of Clinical Pharmacology
- RNA molecules containing exons originating from different members of the cytochrome P450 2C gene subfamily (CYP2C) in human epidermis and liverPeter G. Zaphiropoulos · 1999 · Nucleic Acids Research
- Elevation of steady-state diazepam levels by cimetidineUlrich E. Klotz, Ingrid W. Reimann · 1981 · Clinical Pharmacology & Therapeutics
- Omeprazole and CYP2C19 polymorphism: effects of long‐term treatment on gastrin, pepsinogen I, and chromogranin A in patients with acid related disordersM. Sagar, Leif Bertilsson, Mats Stridsberg, A. Kjellin, Sven Mårdh, Rein Seensalu · 2000 · Alimentary Pharmacology & Therapeutics
- Family studies of mephenytoin hydroxylation deficiency.T. Inaba, M Jurima, WERNER KALOW · 1986 · PubMed
- The Role of CYP2C in the In Vitro Bioactivation of the Contraceptive Steroid DesogestrelDaniela M. Gentile, Carole Verhoeven, Tsutomu Shimada · 1998 · Journal of Pharmacology and Experimental Therapeutics
- Diazepam–omeprazole inhibition interaction: an in vitro investigation using human liver microsomesKatayoun Zomorodi, J. Brian Houston · 1996 · British Journal of Clinical Pharmacology
- Why are diazepam metabolism and polymorphic S-mephenytoin hydroxylation associated with each other in white and Korean populations but not in Chinese populations?Leif Bertilsson, WERNER KALOW · 1993 · Clinical Pharmacology & Therapeutics
- Flunitrazepam oxidative metabolism in human liver microsomes: involvement of CYP2C19 and CYP3A4Janet K. Coller, Andrew Alexander Somogyi, Felix Bochner · 1999 · Xenobiotica
- Pharmacokinetic Fluvoxamine - Clomipramine Interaction with Favorable Therapeutic Consequences in Therapy-resistant Depressive PatientPhilippe Conus, Guido Bondolfi, Chin B. Eap · 1996 · Pharmacopsychiatry
- Effect of ketoconazole on the pharmacokinetics of imipramine and desipramine in healthy subjectsEdoardo Spina, Angela Avenoso, Giuseppe Maurizio Campo · 1997 · British Journal of Clinical Pharmacology
- S-mephenytoin 4-hydroxylation in older AmericansBruce G. Pollock, J M Perel, Margaret A. Kirshner · 1991 · European Journal of Clinical Pharmacology
- Age‐dependent stereoselective increase in the oral clearance of hexobarbitone isomers caused by rifampicin.DA Smith, MH Chandler, Steven I. Shedlofsky · 1991 · British Journal of Clinical Pharmacology
- The elimination of diazepam in Chinese subjects is dependent on the mephenytoin oxidation phenotypeJIE WAN, HUI XIA, Nan He · 1996 · British Journal of Clinical Pharmacology
- The importance of substrate concentration in determining cytochromes P450 therapeutically relevant in vivoRyuichi Kato, Yasushi Yamazoe · 1994 · Pharmacogenetics
- Phenocopies of poor metabolizers of omeprazole caused by liver disease and drug treatment.Karl Ludwig Rost, Jürgen Brockmöller, Friederike Esdorn · 1995 · PubMed
- The elimination of diazepam in Chinese subjects is dependent on the mephenytoin oxidation phenotypeJIE WAN, HUI XIA, Nan He · 1996 · British Journal of Clinical Pharmacology
- Stereoselective 4′‐hydroxylation of phenytoin: relationship to (S)‐mephenytoin polymorphism in JapaneseIchiro Ieiri, Kohsuke Mamiya, Akinori Urae et al. · 1997 · British Journal of Clinical Pharmacology
- CYP2C19 genotyping and associated mephenytoin hydroxylation polymorphism in a Canadian Inuit populationMallé Jurima‐Romet, Joyce A. Goldstein, Michael J. LeBelle · 1996 · Pharmacogenetics
- Possible association between poor metabolism of mephenytoin and hepatotoxicity caused by Atrium®, a fixed combination preparation containing phenobarbital, febarbamate and difebarbamateYves Horsmans, Dominique Lannes, Dominique Pessayre, Dominique G. Larrey · 1994 · Journal of Hepatology
- Stereoselectivity of differential routes of drug metabolism: the fate of the enantiomers of [14C]mephenytoin in the dog.Adrian Kupfer, Johannes Bircher · 1979 · Journal of Pharmacology and Experimental Therapeutics
- Stereospecific analysis of omeprazole supports artemisinin as a potent inducer of CYP2C19Kazuo Mihara, Ulrika S.H. Svensson, Gunnel Tybring · 1999 · Fundamental and Clinical Pharmacology
- Effect of Sertraline on the Pharmacokinetics and Protein Binding of Diazepam in Healthy VolunteersMark Gardner, Barbara A. Baris, Keith D. Wilner, Sheldon Preskorn · 1997 · Clinical Pharmacokinetics
- Genetic polymorphism of the hepatic cytochrome P450 2C19 in North Indian subjects*Jatinder Kaur Lamba, Radha Krishan Dhiman, Krishan Kumar Kohli · 1998 · Clinical Pharmacology & Therapeutics
- Mephenytoin and sparteine oxidation: genetic polymorphisms in Denmark.A Drohse, Lise Bathum, Kim Brøsen · 1989 · British Journal of Clinical Pharmacology
- The steady-state pharmacokinetics of phenytoin (Dilantin) and topiramate (Topamax) in epileptic patients on monotherapy and during combination therapyL.G. Gisclon · 1994 · Epilepsia
- Pharmacokinetic Optimisation of the Treatment of PsychosisA. E. Balant-Gorgia, Luc P. Balant, A. Andreoli · 1993 · Clinical Pharmacokinetics
- Genotype analysis of the CYP2C19 gene in HCV-seropositive patients with cirrhosis and hepatocellular carcinomaTommy Chau, Shigeto MURAKAMI, Bumpei Kawai · 2000 · Life Sciences
- CYP2D6 and CYP2C19 genotypes of patients with terodiline cardiotoxicity identified through the yellow card systemGary A. Ford, Susan M. Wood, Ann K. Daly · 2000 · British Journal of Clinical Pharmacology
- Dapsone N-acetylation, metoprolol α-hydroxylation, and S-mephenytoin 4-hydroxylation polymorphisms in an Indonesian population: A cocktail and extended phenotyping assessment trialRianto Setiabudy, Meizoh Kusaka, Kan Chiba · 1994 · Clinical Pharmacology & Therapeutics
- Stereoselective metabolism and pharmacogenetic control of 5-phenyl-5-ethylhydantoin (nirvanol) in humans.Adrian Kupfer, Rashmi V. Patwardhan, Stephen Andrew Ward · 1984 · Journal of Pharmacology and Experimental Therapeutics
- Genetic polymorphism of S-mephenytoin 4'-hydroxylation.H I Daniel, Edeki Ti · 1996 · PubMed
- Four-week treatment with omeprazole increases the metabolism of caffeine.J.‐B. Nousbaum, Francois Berthou, D Carlhant · 1994 · PubMed
- Mephenytoin hydroxylation in the Cuna Amerindians of Panama.T. Inaba, LF Jorge, TD Arias · 1988 · British Journal of Clinical Pharmacology
- Pharmacogenetic characteristics of the eosinophilia-myalgia syndromeDavid Alastair Flockhart, Daniel Joseph Clauw, Elaine T. Buchert, Jan Hewett, Raymond L. Woosley · 1994 · Clinical Pharmacology & Therapeutics
- Allele frequency of CYP2C19 in a Portuguese populationJorge Lira Ruas, Maria Celeste Lechner · 1997 · Pharmacogenetics
- Phenocopies of poor metabolizers of omeprazole caused by liver disease and drug treatmentKarl Ludwig Rost, Jürgen Brockmöller, Friederike Esdorn · 1995 · Journal of Hepatology
- Imipramine demethylation in vivo: Impact of CYP1A2, CYP2C19, and CYP3A4*Hanne Madsen, Birgitte Buur Rasmussen, Kim Brøsen · 1997 · Clinical Pharmacology & Therapeutics
- P-Hydroxylation of Phenobarbital: Relationship to (s)-Mephenytoin Hydroxylation (CYP2C19) PolymorphismAtsuko Hadama, Ichiro Ieiri, Toshihiro Morita et al. · 2001 · Therapeutic Drug Monitoring
- Evaluation of a Potential Enantioselective Interaction Between Ticlopidine and Warfarin in Chronically Anticoagulated PatientsBarry E. Gidal, Christine A. Sorkness, Kelly A. McGill · 1995 · Therapeutic Drug Monitoring
- Potential Pharmacokinetic Interaction between Felbamate and PhenobarbitalBarry E. Gidal, Mary L. Zupanc · 1994 · Annals of Pharmacotherapy
- Concurrent use of more than one major psychotropic drug (polypsychopharmacy) in out‐patients—a prescription database study.J.-U. Rosholm, Jesper Hallas, LF Gram · 1994 · British Journal of Clinical Pharmacology
- The genetic defect of mephenytoin hydroxylationWERNER KALOW · 1986 · Xenobiotica
- Effects of ketoconazole on the polymorphic 4‐hydroxylations of S‐ mephenytoin and debrisoquine.JO Atiba, Terrence F. Blaschke, G R Wilkinson · 1989 · British Journal of Clinical Pharmacology
- Pharmacokinetic and pharmacodynamic interactions between fluoxetine and moclobemide in the investigation of development of the “serotonin syndrome”*Jasper Dingemanse, Andreas Wallnöfer, Ronald Gieschke · 1998 · Clinical Pharmacology & Therapeutics
- Proguanil polymorphism does not affect the antimalarial activity of proguanil combined with atovaquone in vitroMichael D. Edstein, Anthony E. T. Yeo, Dennis E. Kyle · 1996 · Transactions of the Royal Society of Tropical Medicine and Hygiene
- The N-demethylation of imipramine correlates with the oxidation of S-mephenytoin (S/R-ratio). A population study.Erik Skjelbo, L. F. Gram, Kim Brøsen · 1993 · PubMed
- Cimetidine interaction with amitriptylineStephen H. Curry, C. Lindsay DeVane, M. Michael Wolfe · 1985 · European Journal of Clinical Pharmacology
- Biliary excretion of intravenous [14C] omeprazole in humansTore Lind, Tommy Andersson, Inger Skånberg · 1987 · Clinical Pharmacology & Therapeutics
- Debrisoquine and mephenytoin oxidation in Sinhalese: a population study.K Weerasuriya, RL Jayakody, CA Smith · 1994 · British Journal of Clinical Pharmacology
- Role of CYP2C19 in stereoselective hydroxylation of mephobarbital by human liver microsomes.Kaoru Kobayashi, Mari Kogo, Masayoshi Tani · 2001 · PubMed
- Elevation of plasma phenytoin by viloxazine in epileptic patients: a clinically significant drug interaction.F Pisani, A. Fazio, Catalina Julia Artesi · 1992 · Journal of Neurology Neurosurgery & Psychiatry
- Cimetidine alters the disposition kinetics of the monoamine oxidase-A inhibitor moclobemideMarie‐Paule Schoerlin, Michael Mayersohn, B. Hoevels · 1991 · Clinical Pharmacology & Therapeutics
- Acute Phenytoin Toxicity Followed by Seizure Breakthrough From a Ticlopidine-Phenytoin InteractionMichael Privitera, Timothy E. Welty · 1996 · Archives of Neurology
- The relationship between phenytoin pharmacokinetics and the CYP2C19 genotype in Japanese epileptic patients.Masao Watanabe, K Iwahashi, Toshiaki Kugoh · 1998 · PubMed
- Effect of omeprazole on the pharmacokinetics of sustained-release carbamazepine in healthy male volunteersR.K. Dixit, Chawla, A.B., Narinder Kumar · 2001 · Methods and Findings in Experimental and Clinical Pharmacology
- CYP2C19 genotypes and omeprazole metabolism after single and repeated dosing when combined with clarithromycinQian Zhou, Isamu Yamamoto, Tsuyoshi Fukuda · 1999 · European Journal of Clinical Pharmacology
- Frequency of S-mephenytoin hydroxylation deficiency in 373 spanish subjects compared to other Caucasian populationsJesús Reviriego, Leif Bertilsson, Juan Antonio Carrillo · 1993 · European Journal of Clinical Pharmacology
- Diazepam-Cimetidine Drug InteractionRichard L. Ruffalo, John F. Thompson, Jack L. Segal · 1981 · Southern Medical Journal
- Theophylline pharmacokinetics are not altered by lansoprazole in CYP2C19 poor metabolizersJung Min Ko, In‐Jin Jang, J SHIN · 1999 · Clinical Pharmacology & Therapeutics
- Ticlopidine inhibits phenytoin clearanceS DONAHUE, D FLOCKHART, D ABERNETHY · 1999 · Clinical Pharmacology & Therapeutics
- No Interaction of Diazepam on Amitriptyline Disposition in Depressed PatientsKoichi Otani, Conny Nordin · 1987 · Therapeutic Drug Monitoring
- Theophylline steady state pharmacokinetics is not altered by omeprazoleAnne Marie Taburet, Jean Genève, Muriel Bocquentin · 1992 · European Journal of Clinical Pharmacology
- Sparteine and mephenytoin oxidation: Genetic polymorphisms in East and West GreenlandKnud Clasen, Laila Madsen, Kim Brøsen · 1991 · Clinical Pharmacology & Therapeutics
- Debrisoquine and S -mephenytoin hydroxylation polymorphisms in a Russian population living in EstoniaToomas Marandi, Marja‐Liisa Dahl, Lembit Rägo · 1997 · European Journal of Clinical Pharmacology
- Mephenytoin disposition and serum bile acids as indices of hepatic function in chronic viral hepatitis*Patricia A. Arns, Adedayo B. Adedoyin, A DIBISCEGLIE · 1997 · Clinical Pharmacology & Therapeutics
- Comparison of chloroguanide and mephenytoin for the in vivo assessment of genetically determined CYP2C19 activity in humans*Chohreh Partovian, Évelyne Jacqz-Aigrain, A Keundjian · 1995 · Clinical Pharmacology & Therapeutics
- Proton pump inhibitory therapy: then and now.Wolfgang Schepp · 1997 · PubMed
- Induction of imipramine metabolism following barbiturate administration [proceedings]DS Hewick, RG Sparks, IH Stevenson · 1977 · British Journal of Clinical Pharmacology
- Influence of corticosteroid on hexobarbital and tolbutamide dispositionDouwe D. Breimer, Walter Zilly, Erik Arne Richter · 1978 · Clinical Pharmacology & Therapeutics
- Relationship between mephenytoin oxidation polymorphism and phenytoin, methylphenytoin and phenobarbitone hydroxylation assessed in a phenotyped panel of healthy subjects.J.H.M. Schellens, JH van der Wart, Douwe D. Breimer · 1990 · British Journal of Clinical Pharmacology
- Debrisoquin and S‐Mephenytoin Hydroxylation Phenotypes and CYP2D6 Genotypes in an Estonian PopulationToomas Marandi, Marja‐Liisa Dahl, Raul Allan Kiivet · 1996 · Pharmacology & Toxicology
- Lung cancer risk in relation to mephenytoin hydroxylation activitySimone Benhamou, Christine Bouchardy, Pierre Dayer · 1997 · Pharmacogenetics
- S‐mephenytoin, sparteine and debrisoquine oxidation: genetic polymorphisms in a Turkish population.NE Basci, Kim Brøsen, Atilla Bozkurt · 1994 · British Journal of Clinical Pharmacology
- The hydroxylation of omeprazole correlates with S -mephenytoin and proguanil metabolismSelim Kortunay, N. E. Başcı, Atilla Bozkurt · 1997 · European Journal of Clinical Pharmacology
- Polymorphisms in oxidative drug metabolism: relationship to food preference.M R Britto, HE McKean, GG Bruckner · 1991 · British Journal of Clinical Pharmacology
- Frequency of impaired mephenytoin 4′‐hydroxylation in an Indian population [letter]BS Doshi, Kulkarni Rd, Chauhan Bl · 1990 · British Journal of Clinical Pharmacology
- S-Mephenytoin hydroxylation phenotypes in a Jordanian population*Hakam F. Hadidi, Yacoub M. Irshaid, Raymond L. Woosley · 1995 · Clinical Pharmacology & Therapeutics
- Cimetidine-Imipramine Interaction: Case Report and CommentsPeter A. Shapiro · 1984 · American Journal of Psychiatry
- Imipramine metabolism in relation to the sparteine oxidation polymorphism - a family studyHanne Madsen, T S Hansen, Kim Brøsen · 1996 · Pharmacogenetics
- Selective and Potent Inhibition of Human CYP2C19 Activity by a Conformationally Targeted Antipeptide AntibodyTimothy Schulz-Utermoehl, Richard J. Mountfield, Kjeld Madsen · 2000 · Drug Metabolism and Disposition
- Diazepam Treatment Does Not Influence the Debrisoquine or Mephenytoin Hydroxylation Phenotyping TestsEduardo Spina, Anna Lucia Buemi, DREmilio Sanz · 1989 · Therapeutic Drug Monitoring
- Fluoxetine—Imipramine InteractionIracema Leroi, Magdalena A Walentynowicz · 1996 · The Canadian Journal of Psychiatry
- Dose dependent induction of CYP1A2 activity by omeprazole (Antra).Rost Kl, H. Brösicke, Matthias Scheffler · 1992 · PubMed
- Possible Interaction Between Imipramine and ButalbitalKevin W. Garey, Guy W. Amsden, Celeste A. Johns · 1997 · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy
- Cimetidine-imipramine interaction: case report and comments1984 · American Journal of Psychiatry
- Hepatic cytochrome P450 CYP2C activity in psoriasis: studies using proguanil as a probe compound: Investigative reportsNuala Ann Helsby · 1998 · Acta Dermato Venereologica
- Genotype analysis of the CYP2C19 gene in HCV-seropositive patients with cirrhosis and hepatocellular carcinoma建雄 鄒 · 2001 · Medical Entomology and Zoology
- Effects of omeprazole and cimetidine on the urinary metabolic ratio of proguanil in healthy volunteersAndrew Alexander Somogyi, HELEN A. REINHARD, Felix Bochner · 1996 · European Journal of Clinical Pharmacology
- Blue-chip technologyDavid Alastair Flockhart, David John Webb · 1998 · The Lancet
- No correlation between side-chain of propranolol oxidation and S-mephenytoin 4'-hydroxylase activity.Hong‐Guang Xie, Zhenhua Xu, Song‐Lin Huang · 1997 · PubMed
- The Relationship between CYP2Cl9 Genotype and Phenytoin Pharmacokinetics in Japanese Epileptic Patients.Masao Watanabe, Kazuhiko Iwahashi, Toshiaki Kugoh · 1996 · てんかん研究