The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Calcium Channel Blockers: Differences Between Subclasses
Abstract
Calcium channel blockers (CCBs) share a common mechanism of action. However, the manner in which they exert their pharmacological effects is different between subclasses. Dihydropyridine (DHP) CCBs tend to be more potent vasodilators than non-dihydropyridine (non-DHP) agents, whereas the latter have more marked negative inotropic effects. Both subclasses have a similar capacity to lower BP; however, non-DHPs appear to offer potential advantages in the management of patients with chronic kidney disease and diabetic nephropathy. Representatives of both classes are now available in fixed-dose combinations containing an ACE inhibitor, the benefits of which include effective 24-hour BP control, a reduced incidence of adverse effects, and improved adherence.
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ACE inhibitors, ARBs and dihydropyridine calcium channel blockers cause vasodilation and reduce arterial blood pressure by reducing total peripheral resistance.
“ACEis and ARBs, as well as CCB-DHP cause vasodilation and, thus, a reduction in arterial blood pressure by reducing total peripheral resistance (36, 37).”
From Discontinuation of afterload-reducing drugs decreases left ventricular outflow tract obstruction in hypertrophic obstructive cardiomyopathy (2024) · cites this paper as [37]
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The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group (2002) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.288.23.2981 · Cited by 5,664
Drug-induced atrioventricular block: prognosis after discontinuation of the culprit drug
Zeltser, D., Justo, D., Halkin, A., Rosso, R., Ish-Shalom, M., Hochenberg, M., & Viskin, S. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.03.057 · Cited by 147
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Derda, A. A., Abelmann, M., Sonnenschein, K., Sieweke, J.-T., Bavendiek, U., Bauersachs, J., Thum, T., & Berliner, D. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1403422 · Cited by 6
Metadata
- Authors
- Frishman, W. H.
- Venue
- American Journal of Cardiovascular Drugs
- Published
- 2007
- Volume
- 7
- Issue
- Suppl 1
- Pages
- 17???23
- ISSN
- 1175-3277
- Cited by
- 52
- References
- 2
- Language
- en
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