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The Wide Pharmacological Versatility of Semicarbazones, Thiosemicarbazones and Their Metal Complexes
Abstract
The more significant bioactivities of a variety of semicarbazones (anti-protozoa, anticonvulsant) and thiosemicarbazones (antibacterial, antifungal, antitumoral, antiviral) and their metal complexes are reviewed together with proposed mechanisms of action and structure-activity relationships. Clinical or potential pharmacological applications of these versatile compounds are discussed. Keywords: Semicarbazones, thiosemicarbazones, biological activity, pharmacological applications, bioactive metal complexes, mechanisms of action
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Cited by
Nepali, K., Sharma, S., Sharma, M., Bedi, P. M. S., & Dhar, K. L. (2014) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2014.03.018 · Cited by 435
Degola, F., Morcia, C., Bisceglie, F., Mussi, F., Tumino, G., Ghizzoni, R., Pelosi, G., Terzi, V., Buschini, A., Restivo, F. M., et al. (2015) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2015.02.009 · Cited by 46
Javid, J., Aziz-ur-Rehman, Iqbal, J., Ahmed, I., Bhatti, N., Kuznetsov, A., Zafar, F., Ayub, M. A., Mohammed, O. A., Al-Mijalli, S. H., et al. (2026) · Scientific Reports · doi:10.1038/s41598-026-35499-1 · Cited by 1
Metadata
- Venue
- Mini-Reviews in Medicinal Chemistry
- Publisher
- Bentham Science Publishers Ltd.
- Published
- 2004-01-01
- Volume
- 4
- Issue
- 1
- Pages
- 31-39
- ISSN
- 1389-5575 (ISSN-L)
- OpenAlex
- W1486288260
- Cited by
- 777
- References
- 0
- FWCI
- 7.79
- Type
- journal article
- Language
- en
- Open access
- closed
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