Cited by 351Medical Imaging Techniques and ApplicationsBreast Lesions and CarcinomasCancer Diagnosis and Treatment

The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.

FDG PET Evaluation of Mucinous Neoplasms: Correlation of FDG Uptake with Histopathologic Features

Berger, Kevin L., Nicholson, Siobhan A., Dehdashti, Farrokh, Siegel, Barry A.·2000·American Journal of Roentgenology

Open this paper in CoChat — free account

Abstract

Objective Our goal was to assess the sensitivity of positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) for the detection of mucinous carcinoma and to determine the histologic features of these tumors that may affect lesion detectability. Materials and methods A retrospective review of all patients with mucinous carcinoma who had undergone FDG PET at our institution from 1995 through 1998 identified 25 patients with new or recurrent mucinous carcinoma at the time of PET. In 22 of these patients, tissue specimens available from either core biopsy or surgical resection allowed detailed histologic analysis. Results FDG PET revealed mucinous carcinoma in only 13 (59%) of 22 patients, resulting in an unusually high percentage (41%) of false-negative results. Two histologic features were found to be predictive of FDG PET results: tumor cellularity (p = 0.011) and the amount of mucin within the tumor mass (p = 0.009). There was a positive correlation between tumor FDG uptake and cellularity but a negative correlation with the amount of mucin. Conclusion FDG PET is limited in the evaluation of mucinous tumors, particularly in hypocellular lesions with abundant mucin.

Integrity signals

Registry

Crossref · 10.2214/ajr.174.4.1741005

Cites

25 of 25 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cancer: Principles and Practice of Oncology.
(1991) · Annals of Internal Medicine · doi:10.7326/0003-4819-114-9-819_4 · Cited by 8,524
Oncological applications of positron emission tomography with fluorine-18 fluorodeoxyglucose
Rigo, P., Paulus, P., Kaschten, B., Hustinx, R., Bury, T., Jerusalem, G., Benoit, T., & Foidart-Willems, J. (1996) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/bf01249629 · Cited by 496
Histological Typing of Breast Tumors
Azzopardi, J. G., Chepick, O. F., Wh, H., Jafarey, N. A., Llombard-Bosch, A., Ozzello, L., Rilke, F. O., Sasano, N., Sobin, L. H., Sommers, S. C., et al. (1982) · Tumori Journal · doi:10.1177/030089168206800301 · Cited by 444
Lymph node staging in non-small-cell lung cancer with FDG-PET scan: a prospective study on 690 lymph node stations from 68 patients.
Vansteenkiste, J., Stroobants, S. G., Leyn, P. R. D., Dupont, P. J., Bogaert, J. G., Maes, A., Deneffe, G. J., KL, N., Verschakelen, J., Lerut, A., et al. (1998) · Journal of Clinical Oncology · doi:10.1200/jco.1998.16.6.2142 · Cited by 408
Evaluation of breast masses and axillary lymph nodes with [F-18] 2-deoxy-2-fluoro-D-glucose PET.
Adler, L. P., Crowe, J. P., Al-Kaisi, N. K., & Sunshine, J. L. (1993) · Radiology · doi:10.1148/radiology.187.3.8497624 · Cited by 372
Does FDG uptake measure proliferative activity of human cancer cells? In vitro comparison with DNA flow cytometry and tritiated thymidine uptake.
Higashi, K., Clavo, A. C., & Wahl, R. L. (1993) · PubMed · Cited by 311
Staging of esophageal cancer with 18F-fluorodeoxyglucose positron emission tomography.
Flanagan, F. L., Dehdashti, F., Siegel, B. A., Trask, D. D., Sundaresan, S. R., Patterson, G. A., & Cooper, J. D. (1997) · American Journal of Roentgenology · doi:10.2214/ajr.168.2.9016218 · Cited by 310
Self-citation
Risk of malignancy in thyroid incidentalomas identified by fluorodeoxyglucose-positron emission tomography
Cohen, M. S., Arslan, N., Dehdashti, F., Doherty, G. M., Lairmore, T. C., Brunt, L. M., & Moley, J. F. (2001) · Surgery · doi:10.1067/msy.2001.118265 · Cited by 306
Self-citation
Staging recurrent metastatic colorectal carcinoma with PET.
Delbeke, D., Vitola, J. V., Sandler, M. P., Arildsen, R. C., Powers, T., Wright, J. K., Chapman, W. C., & Pinson, C. W. (1997) · PubMed · Cited by 292
Detection of recurrent and metastatic colorectal cancer: Comparison of positron emission tomography and computed tomography
Ogunbiyi, O. A., Flanagan, F. L., Dehdashti, F., Siegel, B. A., Trask, D. D., Birnbaum, E. H., Fleshman, J. W., Read, T. E., Philpott, G. W., & Kodner, I. J. (1997) · Annals of Surgical Oncology · doi:10.1007/bf02303744 · Cited by 268
Self-citation

Show all 25 references

Research works printed but not linked: 1

Rosai J. Special techniques in surgical pathology. In: Rosai J, ed. Ackerman's surgical pathology , 8th ed. St. Louis: Mosby-Year Book, 1996: 31-62

Sorted by citations

Items 301–351 of 351

Correspondence: Diagnostic accuracy of 18F-FDG PET/CT in characterizing ovarian lesions
Tuncel, M. (2007) · Nuclear Medicine Communications · doi:10.1097/mnm.0b013e3282f12698
PET and TNM: evolution or revolution?
Cheow, H., Mikhaeel, N. G., & O'Doherty, M. J. (2006) · Nuclear Medicine Communications · doi:10.1097/01.mnm.0000199472.23654.bd
Tomographie par émission de positons en cancérologie digestive
Montravers, F., & Talbot, J. (2012) · EMC - Radiologie et imagerie médicale - Abdominale - Digestive · doi:10.1016/s1879-8527(12)55045-8
Positronenemissionstomographie zur Diagnostik von Gallenblasen- und Gallenwegkarzinomen
Kluge, R. (2004) · Visceral Medicine · doi:10.1159/000083010
False-Negative 18F-FDG PET Results in Lymph Node Metastasis of A Patient with Follicular Thyroid Carcinoma: A Case Report and Literature Review
Sun, S., & Kao, C. (2001) · 核子醫學雜誌 · doi:10.6332/anms.1403.018
Mucinous Cancers: Ovary
Ledermann, J. A., & Raja, F. A. (2010) · Springer eBooks · doi:10.1007/978-3-642-13492-0_5
[Our observations on hearing, equilibrium and vision disorders as well as factors predisposing to these disorders following streptomycin treatment].
Miszke, A. (1973) · PubMed
Chapter 24 – The Colon and Rectum
Janjan, N. A., Delclos, M. E., Crane, C. H., Krishnan, S., & Das, P. (2010)
Usefulness of $^{18}F$-FDG Uptake Value Assay in the Differential Diagnosis of the Colorectal Polyp: Case Report
Bahk, Y.-W., & Kang, Y.-M. (2007) · Nuclear Medicine and Molecular Imaging
Imaging in gynecology
Freeman, S. J., & Sala, E. (2015) · Cambridge University Press eBooks · doi:10.1017/cbo9781139628938.016
Whole-body MR-DWIBS vs. ( 18 F)-FDG-PET/CT in the study of malignant tumors: a retrospective study Whole-body RM-DWIBS vs. 18 F-FDG-PET/TC nelle neoplasie maligne: studio retrospettivo di confronto
Cafagna, D., Rubini, G., Iuele, F., Maggialetti, N., Notaristefano, A., Pinto, D., Asabella, A. N., Palmiotti, G., Lasciarrea, M., & Maggialetti, A. (2012)
Feasibility of F-18-FDG PET/CT Scan for in Abdomino-pelvic Regions -The 2nd Chapter-
Suga, K. (2008) · Yamaguchi Medical Journal · doi:10.2342/ymj.57.171
Staging of Colorectal Cancer
Mehta, P., & Colletti, P. M. (2014)
Uso da tomografia por emissão de pósitrons/ressonância magnética (PET/RM) para o estadiamento de pacientes portadores de câncer retal
Queiroz, M. A. (2020) · doi:10.11606/t.5.2020.tde-25062021-111748
PET/CT imaging in colorectal carcinoma
Boktor, R. R., Lee, S. T., & Scott, A. M. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-822960-6.00033-8
Molecular imaging using positron emission tomography in gastrointestinal malignancy
Pakzad, F. (2010) · UCL Discovery (University College London)
Oncology: Hepatic cancer
Ho, C. L., & Chen, S. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822960-6.00109-5
Uncommon Tumors of the Gastrointestinal Tract in Children
Pappo, A. S., & Furman, W. L. (2017) · doi:10.1002/9781119196235.ch74
Pancreas
(2006) · Springer eBooks · doi:10.1007/1-84628-169-5_9
Colorectal Cancer
Tan, C. H., Morris, V. K., Das, P., Rodrı́guez-Bigas, M. A., & Iyer, R. B. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-69538-1.00018-5
Colorectal Cancer
Granov, A., Tiutin, L., & Schwarz, T. (2011) · Springer eBooks · doi:10.1007/978-3-642-21120-1_8
Oncology—Digestive Tract
(2005) · Springer eBooks · doi:10.1007/1-84628-100-8_8
Colorectal Carcinoma
Delbeke, D., Komori, T., & Martin, W. H. (2002) · Springer eBooks · doi:10.1007/978-0-387-22453-4_10
Case 32: Mucinous Colonic Adenocarcinoma
Wong, C. Y. O., & Wu, D. (2022) · Springer eBooks · doi:10.1007/978-3-031-09737-9_32
Case 10: Metabolic Phenotype in Lung Metastasis from Colon Cancer
Wong, C. Y. O., & Wu, D. (2022) · Springer eBooks · doi:10.1007/978-3-031-09737-9_10
Review on Diagnosis and Management of Colorectal Carcinoma
Donkol, A., AlSomali, R. A., Alshammari, A. M., AlKhamis, H. A., Alharbi, L. K., AlHazmi, A. A., Daiel, A. A. M., Mohzari, D. A. M., Hejres, A. J., AlRefaei, N. A., et al. (2022) · Clinical Cancer Investigation Journal · doi:10.51847/dxsj8lrq5w
PET-CT/MR Imaging in Head and Neck Cancer: Physiologic Variations, Pitfalls, and Directed Applications
Loevner, L. A. (2023) · Springer eBooks · doi:10.1007/978-3-031-10909-6_48
Contribution of 18F-FDG PET/MR Imaging in Detection of Peritoneal Carcinomatosis in Patients with Ovarian CancerPreprint
Baltacıoğlu, M. H., Soydal, Ç., Araz, M., Öz, D. K., Taşkın, S., Kucuk, N. O., Erden, G. A., & Elhan, A. H. (2023) · Research Square · doi:10.21203/rs.3.rs-3256773/v1
Approach to Lung Nodules
Vedachalam, S., Tanner, N. T., & Sears, C. R. (2023) · Respiratory medicine · doi:10.1007/978-3-031-38412-7_4
Analysis of discordant PET and CT findings in 18F-FDG PET-CT scans in the management of oncology patients
Sunny, S., Oommen, R., Hephzibah, J., Shanthly, N., Mathew, D., & Eapen, A. (2023) · Indian Journal of Cancer · doi:10.4103/ijc.ijc_1202_20
A 45-Year-Old Woman With a Persistent Cavitary Consolidation
Jain, A., Hara, N., Keller, M., Han, L., & Epelbaum, O. (2024) · CHEST Pulmonary · doi:10.1016/j.chpulm.2024.100104
Primary mucinous carcinoma of the scalp
Greef, A. D., Landen, L., Fierens, H., & Baeck, M. (2024) · BMJ Case Reports · doi:10.1136/bcr-2024-260991
Mucinous rectal adenocarcinoma recurrence: A case report and literature review
Sood, R., Badjatia, T., & Bhargava, P. (2025) · Radiology Case Reports · doi:10.1016/j.radcr.2025.01.046
Maximum Surgical Resection Followed by Radiation Therapy for the Management of Mucinous Adenocarcinoma of the Prostate
Patel, K. R., & Hall, W. A. (2025) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2024.11.007
Diagnostic du cancer pulmonaire en imagerie : pièges à connaître
Dobre, M., Fawaz, S., Caramella, C., & de Margerie‐Mellon, C. (2025) · Journal d imagerie diagnostique et interventionnelle · doi:10.1016/j.jidi.2025.02.002
In Vivo Interrogation of Cell-Penetrating Peptide Function: Accumulation in Tumors and the Potential as a Specific PET Probe
Si, Z., Tian, L., Zhou, H., Lin, J., & Zhou, J. (2025) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.5c00128
Exenteración pélvica: ¿cuál es el papel del radiólogo?
Salgado-Parente, A., Campo, L. G., Campos, A. V., Pérez, J. C. G., Beltrán, M. M., & Lachén, E. C. (2025) · Radiología · doi:10.1016/j.rx.2025.501690
Cavitary Lung Disease
Hasan, A. (2025) · Springer eBooks · doi:10.1007/978-981-96-7810-5_32
PET/CT in Hepatobiliary Pancreatic Tumours
Shaikh, S. (2025) · Springer eBooks · doi:10.1007/978-981-95-1699-5_18
Gastric mucinous adenocarcinoma presenting with chronic cough, bronchovascular bundle thickening, and multiple pulmonary nodules: a case report
Huang, H., Chen, F., Huang, H., Su, X., & Duan, M. (2026) · Frontiers in Oncology · doi:10.3389/fonc.2026.1713925
Radiomics’ Role in Predicting Distant Metastases, Recurrence and Survival Outcome in Rectal Cancer: A Systematic Review
Mohammed, H. M. A., Mohamed, H., Fofana, M., Jawaid, S., Hersi, M., Alwani, O., Nair, R., & Sagar, J. (2026) · Cancers · doi:10.3390/cancers18091440
Pelvic exenteration: The radiologist’s role
Salgado-Parente, A., González-Campo, L., Campos, A. V., Pérez, J. C. G., Beltrán, M. M., & Lachén, E. C. (2026) · Radiología (English Edition) · doi:10.1016/j.rxeng.2026.501690
Accuracy of PET/CT for the Detection of Synchronous Malignant Lesions in Patients With Endoscopically Obstructive Colorectal Cancer
Kulle, C. B., Yıldırım, M. I., Bozkurt, H. A., Işık, E. G., Büyük, M., Berker, N. K., Özgür, İ., Bulut, M. T., Keskin, M., & Bayraktar, A. (2026) · Surgical Laparoscopy Endoscopy & Percutaneous Techniques · doi:10.1097/sle.0000000000001484
The role of 18F-FDG PET/CT in the clinical evaluation of hepatoid adenocarcinoma
Lin, L., Wang, W., Yan, J., Zhang, Y., Yang, S., Wen, X., Zhao, K., Zhang, J., & Su, X. (2026) · Abdominal Radiology · doi:10.1007/s00261-026-05651-6
Surgical Management of Colorectal Cancer Peritoneal Metastases: Current Indications, Controversies, and Future Directions
McCullers, M. R., & Aquina, C. T. (2026) · Digestive Surgery · doi:10.1159/000552611
Applications of [18F]fluorodeoxyglucose PET Imaging in Colorectal Cancer.
Chandekar, K., Karna, R., & Damle, N. (2026) · PET Clinics · doi:10.1016/j.cpet.2026.06.008
The Potential Role of 99mTc-FAPI SPECT/CT in the Staging of Mucinous Appendiceal Adenocarcinoma
Borujerdi, N. R., Rabani, F., Tanha, A. S., Zare, S., & Aghaee, A. (2026) · Clinical Nuclear Medicine · doi:10.1097/rlu.0000000000006513
Fluorodeoxyglucose Metabolic Phenotypes Across Molecular Subgroups of Primary Colorectal Cancer: A Retrospective Three-Group Analysis
Morita, R., Norikane, T., Yamamoto, Y., Manabe, Y., Murao, M., Obata, T., Mitamura, K., Okuyama, H., & Nishiyama, Y. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15187113
Comparison of metabolic variables in FDG PET/CT in rectal cancer patients who achieved a complete or incomplete response following neoadjuvant chemoradiotherapy.
Amaral, K. M. D., Siqueira, R. M., Arab, N. A., Etchebehere, E., de Lima, M. D. C. L., Santos, A. D. O., Ramos, C. D., de Souza, T. F. D., Brunetto, S., de Souza, E. M., et al. (2026) · Annals of Nuclear Medicine · doi:10.1007/s12149-026-02285-y
Diagnostic value of fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography in staging histological subtypes of invasive bladder cancer
Lijnen, R. A. G., Ringia, J. B., Claps, F., Vogel, W. V., Boellaard, T. N., van Rhijn, B. W., Braat, A. J. A. T., & Mertens, L. S. (2026) · Tijdschrift voor Urologie · doi:10.1007/s13629-026-00514-7
Integrated PET-CT and PET-MR: Pitfalls and Applications in Head and Neck Squamous Cell Carcinoma
Loevner, L. A. (2012) · Springer eBooks · doi:10.1007/978-88-470-2628-5_34

Authors: Berger, K. L., Nicholson, S. A., Dehdashti, F., & Siegel, B. A.
Affiliations: Washington University in St. Louis (US)
ORCID: Dehdashti, Farrokh
Siegel, Barry A.
Venue: American Journal of Roentgenology
Publisher: American Roentgen Ray Society
Published: 2000-04
Volume: 174
Issue: 4
Pages: 1005-1008
ISSN: 0002-9580 (ISSN-L)
0361-803X
1546-3141
DOI: 10.2214/ajr.174.4.1741005
OpenAlex: W1748631556
Cited by: 351
References: 25
Citations by year: 2026: 14 · 2025: 13 · 2024: 10 · 2023: 12 · 2022: 16 · 2021: 13 · 2020: 15 · 2019: 22 · 2018: 9 · 2017: 8 · 2016: 12 · 2015: 12 · 2014: 16 · 2013: 16 · 2012: 24
FWCI: 6.91
Type: journal article
Language: en
Open access: closed
Locations: American Journal of Roentgenology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Medical Imaging Techniques and Applications
Health Sciences › Medicine › Pathology and Forensic Medicine › Breast Lesions and Carcinomas
Health Sciences › Medicine › Oncology › Cancer Diagnosis and Treatment
Keywords: FDG-PET, mucinous carcinoma, 18F-fluorodeoxyglucose, tumor cellularity, false-negative results
MeSH terms: Adult, Aged, Adenocarcinoma, Mucinous, Female, Humans, Male, Middle Aged, Retrospective Studies, Sensitivity and Specificity, Tomography, Emission-Computed, Radiopharmaceuticals, Fluorodeoxyglucose F18

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

FDG PET Evaluation of Mucinous Neoplasms: Correlation of FDG Uptake with Histopathologic Features

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks