Bone Mineral Density Assessment Using Spectral Topograms From a Clinical Photon-Counting Detector CT System: A Phantom Evaluation
Abstract
Bone mineral density assessments in a spine phantom had lower errors by spectral topograms from a clinical photon-counting detector CT scanner than by a DXA system. Bone mineral density assessments by PCD CT also had high reproducibility.
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A previous experimental study with spectral localizer radiographs from PCD-CT using the European Spine Phantom showed that spectral localizer radiographs were more accurate than DXA at higher bone density.
“A previous experimental study with spectral localizer radiographs from PCD-CT using the established European Spine Phantom21 showed that spectral localizer radiographs were more accurate that DXA at higher bone density.13”
From In Vivo Bone Mineral Density Assessment With Spectral Localizer Radiographs From Photon-Counting Detector CT (2025) · cites this paper as [13]
Two phantom studies using a clinically approved PCD-CT scanner confirmed these initial observations and showed accurate results in regard to aBMD quantification as compared with phantom specifications and with the clinical reference standard DXA.
“More recently, 2 phantom studies using a clinically approved PCD-CT scanner confirmed these initial observations and showed accurate results in regard to aBMD quantification as compared with phantom specifications and with the clinical reference standard DXA.12,13”
From In Vivo Bone Mineral Density Assessment With Spectral Localizer Radiographs From Photon-Counting Detector CT (2025) · cites this paper as [13]
Cited by
Sorted by citations
Moser, L. J., Klambauer, K., Diaz Machicado, M. C., Frey, D., Mergen, V., Eberhard, M., Nowak, T., Schmidt, B., Flohr, T., Distler, O., et al. (2025) · Investigative Radiology · doi:10.1097/rli.0000000000001159 · Cited by 8 · see citing works
Self-citation
- Authors
- Moser, L. J., Pitteloud, J., Mergen, V., Frey, D., Nowak, T., Distler, O., Eberhard, M., & Alkadhi, H.
- Affiliations
- University Hospital Zurich (CH)
- Siemens Healthineers (Germany) (DE)
- ORCID
- Venue
- American Journal of Roentgenology
- Publisher
- American Roentgen Ray Society
- Published
- 2024-02
- Volume
- 222
- Issue
- 2
- Pages
- e2330347-e2330347
- ISSN
- 0002-9580 (ISSN-L)
- 0361-803X
- 1546-3141
- OpenAlex
- W4388491191
- Cited by
- 5
- References
- 0
- Citations by year
- 2025: 2 · 2024: 3
- FWCI
- 0.39
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Roentgenology (publishedVersion)
- PubMed (publishedVersion)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Advanced X-ray and CT Imaging
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Physical Sciences › Engineering › Biomedical Engineering › Medical Imaging and Analysis
- Keywords
- bone mineral density, photon-counting CT, spine phantom, dual-energy X-ray absorptiometry comparison, measurement reproducibility, bone densitometry
- MeSH terms
- Humans, Tomography, X-Ray Computed, Bone Density, Photons, Phantoms, Imaging
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