The DOI matches its Crossref record; 115 of the 115 references it cites were found in a registry or an index.
Diagnosis, Epidemiology and Outcomes of Acute Kidney Injury
Abstract
Acute kidney injury is an increasingly common and potentially catastrophic complication in hospitalized patients. Early observational studies from the 1980s and 1990s established the general epidemiologic features of acute kidney injury: the incidence, prognostic significance, and predisposing medical and surgical conditions. Recent multicenter observational cohorts and administrative databases have enhanced our understanding of the overall disease burden of acute kidney injury and trends in its epidemiology. An increasing number of clinical studies focusing on specific types of acute kidney injury (e.g., in the setting of intravenous contrast, sepsis, and major surgery) have provided further details into this heterogeneous syndrome. Despite our sophisticated understanding of the epidemiology and pathobiology of acute kidney injury, current prevention strategies are inadequate and current treatment options outside of renal replacement therapy are nonexistent. This failure to innovate may be due in part to a diagnostic approach that has stagnated for decades and continues to rely on markers of glomerular filtration (blood urea nitrogen and creatinine) that are neither sensitive nor specific. There has been increasing interest in the identification and validation of novel biomarkers of acute kidney injury that may permit earlier and more accurate diagnosis. This review summarizes the major epidemiologic studies of acute kidney injury and efforts to modernize the approach to its diagnosis.
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Cites
Uchino, S. (2005) · JAMA · doi:10.1001/jama.294.7.813 · Cited by 4,176
Acute Kidney Injury, Mortality, Length of Stay, and Costs in Hospitalized Patients
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The natural history of the systemic inflammatory response syndrome (SIRS). A prospective study
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Mehran, R., Aymong, E. D., Nikolsky, E., Lasic, Z., Iakovou, I., Fahy, M., Mintz, G. S., Lansky, A. J., Moses, J. W., Stone, G. W., et al. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.06.068 · Cited by 2,044
A Randomized Trial Comparing Conventional and Endovascular Repair of Abdominal Aortic Aneurysms
Prinssen, M., Verhoeven, E. L. G., Buth, J., Cuypers, P. W. M., van Sambeek, M. R. H. M., Balm, R., Buskens, E., Grobbee, D. E., & Blankensteijn, J. D. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa042002 · Cited by 2,020
Hospital-acquired renal insufficiency
Nash, K., Hafeez, A., & Hou, S. (2002) · American Journal of Kidney Diseases · doi:10.1053/ajkd.2002.32766 · Cited by 1,951
Kidney Injury Molecule-1 (KIM-1): A novel biomarker for human renal proximal tubule injury
Han, W. K., Bailly, V., Abichandani, R., Thadhani, R., & Bonventre, J. V. (2002) · Kidney International · doi:10.1046/j.1523-1755.2002.00433.x · Cited by 1,929
Mishra, J., Ma, Q., Prada, A., Mitsnefes, M., Zahedi, K., Yang, J., Barasch, J., & Devarajan, P. (2003) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000088027.54400.c6 · Cited by 1,749
Incidence and Prognostic Importance of Acute Renal Failure After Percutaneous Coronary Intervention
Rihal, C. S., Textor, S. C., Grill, D. E., Berger, P. B., Ting, H. H., Best, P. J., Singh, M., Bell, M. R., Barsness, G. W., Mathew, V., et al. (2002) · Circulation · doi:10.1161/01.cir.0000016043.87291.33 · Cited by 1,712
Cited by
Acute kidney injury episodes and chronic kidney disease risk in diabetes mellitus
Thakar, C. V., Christianson, A., Himmelfarb, J., & Leonard, A. C. (2011) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.01120211 · Cited by 485
Clinical features and outcomes of immune checkpoint inhibitor-associated AKI: a multicenter study
Cortazar, F. B., Kibbelaar, Z. A., Glezerman, I. G., Abudayyeh, A., Mamlouk, O., Motwani, S. S., Murakami, N., Herrmann, S. M., Manohar, S., Shirali, A. C., et al. (2020) · Journal of the American Society of Nephrology · doi:10.1681/asn.2019070676 · Cited by 407
James, M. T., Grams, M. E., Woodward, M., Elley, C. R., Green, J. A., Wheeler, D. C., de Jong, P., Gansevoort, R. T., Levey, A. S., Warnock, D. G., et al. (2015) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2015.02.338 · Cited by 309
Pathophysiological role of different tubular epithelial cell death modes in acute kidney injury
Sancho-Martínez, S. M., López-Novoa, J. M., & López-Hernández, F. J. (2015) · Clinical Kidney Journal · doi:10.1093/ckj/sfv069 · Cited by 130
Bradshaw, C., Zheng, Y., Silver, S. A., Chertow, G. M., Long, J., & Anand, S. (2018) · Journal of General Internal Medicine · doi:10.1007/s11606-018-4531-6 · Cited by 36
Self-citation
Metadata
- Authors
- Waikar, S. S., Liu, K. D., & Chertow, G. M.
- Venue
- Clinical Journal of the American Society of Nephrology
- Published
- 2008-05
- Volume
- 3
- Issue
- 3
- Pages
- 844-861
- ISSN
- 1555-9041 (ISSN-L)
- OpenAlex
- W2138461176
- Cited by
- 533
- References
- 115
- FWCI
- 16.32
- Type
- journal article
- Language
- en
- Open access
- closed
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- Waikar, S. S., Liu, K. D., & Chertow, G. M. (2008). Diagnosis, Epidemiology and Outcomes of Acute Kidney Injury. Clinical Journal of the American Society of Nephrology. https://doi.org/10.2215/cjn.05191107
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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