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Cited by 22Phytochemicals and Antioxidant ActivitiesMedicinal Plant ResearchAgricultural and Biological Research

The DOI matches its Crossref record; 10 of the 12 references it cites were found in a registry or an index.

ANTIOXIDANT ACTIVITY OF COMBINATION BANANA PEEL (MUSA PARADISIACA) AND WATERMELON RIND (CITRULLUS VULGARIS) EXTRACT IN LOTION DOSAGE FORM

Open access
Alamsyah, Natalia, Djamil, Ratna, Rahmat, Deni·2016·Asian Journal of Pharmaceutical and Clinical Research

Abstract

ABSTRACTObjective: Test the antioxidant activity of banana peel extract, watermelon rind extract, and combinations, also in lotion dosage form.Methods: The antioxidant activity of each extract and their combinations were tested with 2,2-diphenyl-1-picrylhydrazil method and formulated intoa lotion dosage forms. Evaluation of the lotion dosage forms, including organoleptic, homogeneity, pH, viscosity and rheology, microbiology, acutedermal irritation test, as well as the antioxidant activity test.Results: Antioxidant activity test on the extract showed inhibitory concentration 50% (IC50) values of banana peel is 64.03 part per million (ppm)and watermelon rind extract of 300.12 ppm. Combination of banana peel and watermelon rind extract with three different concentrations, IC50:IC50,inhibitory concentration at 75% (IC75):inhibitory concentration at 25% (IC25), IC25:IC75 resulted the best antioxidant activity is a combination of bananapeel, and watermelon rind extract IC75:IC25 with IC50 value of 177.56 ppm. The antioxidant activity test in lotion dosage form showed IC50 values oflotion base is 853.16 ppm, lotion banana peel extract is 472.50 ppm, lotion watermelon rind extract is 496.71 ppm, and the combination of bananapeel and watermelon rind extract are 300.04 ppm.Conclusion: Lotion dosage form formula that meets the requirements of quality, efficacy, and safety with the best antioxidant activity is lotion dosageform combination of banana peel and watermelon rind extract formula (IC75:IC25).Keywords: Antioxidant activity, Banana peel (Musa paradisiaca), Watermelon rind (Citrullus vulgaris), Combination of banana peel and watermelonrind extract, Lotion of antioxidant.

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Crossref · 10.22159/ajpcr.2016.v9s3.14926

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Cites

Research works printed but not linked: 7

  1. Mandal S, Yadav S, Nema RK. Antioxidants: A review. J Chem Pharm Res 2009;1(1):102-4.
  2. Someya S, Yoshiki Y, Okubo K. Antioxidant compounds from banana. Food Chem 2002;79(3):351-4.
  3. Ismayanti I, Bahri S, Nurhaeni N. The study of phenolics content and antioxidant activities of watermelon rind juice (Citrullus lanatus). Online J Nat Sci 2013;2(2):36-45.
  4. Blois MS. Antioxidant determination by the use of stable free radicals. Nature 1958;181:1199-2000.
  5. Hodisan T, Juncan AM. Analysis of Some Antioxidants Used in Cosmetics by Chromatographic Methods [Thesis]. Romania: Faculty of Chemistry and Chemical Engineering University Cluj-Napoca; 2011. p. 10-1.
  6. Khatua S, Roy T, Acharya K. Antioxidant and free radical scavenging capacity of phenolic extract from Russula laurocerasi. Asian J Pharm Clin Res 2013;6(4):156-60.
  7. Mitsui T. New Cosmetic Science. Amsterdam: Elsevier; 1997. p. 327-31.

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Metadata

Authors
Alamsyah, N., Djamil, R., & Rahmat, D.
Affiliations
Pancasila University (ID)
Venue
Asian Journal of Pharmaceutical and Clinical Research
Published
2016-12-01
Volume
9
Issue
9
Pages
300
ISSN
  • 0974-2441 (ISSN-L)
  • 2455-3891
OpenAlex
W2558031388
Cited by
22
References
12
Citations by year
2026: 1 · 2025: 4 · 2024: 1 · 2023: 7 · 2022: 4 · 2021: 4 · 2020: 1
FWCI
0.00
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
Asian Journal of Pharmaceutical and Clinical Research (publishedVersion, cc-by-nc)
Topics
  • Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural and Biological Research
Keywords
antioxidant activity, banana peel extract, Musa paradisiaca, Citrullus vulgaris, topical formulation, IC50, skin irritation

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