THE INVESTIGATION OF THE DEVELOPMENT OF A CREAM COMPOSITION WITH THE SAPROPEL EXTRACT
Open accessAbstract
Objective: The objective of this research was the development of cream with sapropel extract on the emulsifying base and the investigation of the possibility for cream samples to be in future applied in medicine, cosmetics, and veterinary.Methods: To carry out the research a set of methods (centrifugal, thermal, and potentiometric) to analyze colloidal and thermal stability and determine pH values of the tested samples were used. Organoleptic characteristics of the tested samples and possible signs of physical instability were studied. Rheological properties of the samples were determined on the rotating viscometer. The method of microscopic analysis was carried out to analyze the stability of the emulsion system.Results: The research outcomes revealed that all the prototype samples have thermal and colloid stability, neutral pH value, and consistency that depends on the content of the oil phase and the emulsifying mixture. The samples, containing 15% of Vaseline oil and 4% and 6% of emulsifier no. 1, have low viscosity indexes, and the sample with 10% of emulsifier has a rather dense consistency. The samples containing 20% of oil phase possess unsatisfactory organoleptic properties. Since the sample with 4% of emulsifier possessed low rates of viscosity and phase separation occurred during its storage.Microscopic studies have shown that the sample containing 6% of emulsifier no. 1 exhibits monodisperse and a uniform roundness of drops that indicates the stability of the system.Conclusion: The outcome of the research is the development of the composition of the cream with sapropel extract with the emulsifying base containing 15% of corn oil, 6% of emulsifier no. 1, and 1% of Cetostearyl alcohol and purified water.
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The stratum corneum's ability to shield the skin against some irritants, such as allergies, chemotherapeutics, or dermatitis, may not be sufficient.
“The stratum corneum's ability to shield the skin against some irritants, such as allergies, chemotherapeutics, or dermatitis, may not be sufficient [78].”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [78]
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References 6 · Cited by 13
- Authors
- Strus, O., Polovko, N., & Plaskonis, Y.
- Affiliations
- Danylo Halytsky Lviv National Medical University (UA)
- National University of Pharmacy (UA)
- Venue
- Asian Journal of Pharmaceutical and Clinical Research
- Publisher
- Innovare Academic Sciences Pvt Ltd
- Published
- 2018-07-07
- Volume
- 11
- Issue
- 7
- Pages
- 147
- ISSN
- 0974-2441 (ISSN-L)
- 2455-3891
- OpenAlex
- W2843245997
- Cited by
- 13
- References
- 6
- Citations by year
- 2025: 3 · 2024: 2 · 2023: 1 · 2022: 1 · 2021: 1 · 2020: 3 · 2019: 2
- FWCI
- 0.61
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by-nc
- Locations
- Asian Journal of Pharmaceutical and Clinical Research (publishedVersion, cc-by-nc)
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Surfactants and Colloidal Systems
- Health Sciences › Health Professions › Complementary and Manual Therapy › Therapeutic Uses of Natural Elements
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
- Keywords
- cream formulation, emulsion stability, thermal stability, colloidal stability, rheological properties, viscosity, cetostearyl alcohol, corn oil, vaseline oil, phase separation, cosmetic formulation
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