The DOI matches its Crossref record; 112 of the 112 references it cites were found in a registry or an index.
Neutrophil Gelatinase-Associated Lipocalin: A� Promising Biomarker for Human Acute Kidney Injury
Open accessAbstract
Acute kidney injury (AKI) is a common and serious condition, the diagnosis of which depends on serum creatinine measurements. Unfortunately, creatinine is a delayed and unreliable indicator of AKI. The lack of early biomarkers has crippled our ability to translate promising experimental therapies to human AKI. Fortunately, understanding the early stress response of the kidney to acute injuries has revealed a number of potential biomarkers. The discovery, translation and validation of neutrophil gelatinase-associated lipocalin, arguably the most promising novel AKI biomarker, are reviewed in this article. Neutrophil gelatinase-associated lipocalin is emerging as an excellent standalone troponin-like biomarker in the plasma and urine for the prediction of AKI, monitoring clinical trials in AKI and for the prognosis of AKI in several common clinical scenarios.
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3 retracted
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RetractedBoldt, J., Suttner, S., Brosch, C., Lehmann, A., Röhm, K. D., & Mengistu, A. (2009) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e3181b5a24b · Cited by 87
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Uchino, S. (2005) · JAMA · doi:10.1001/jama.294.7.813 · Cited by 4,176
Mishra, J., Dent, C., Tarabishi, R., Mitsnefes, M. M., Ma, Q., Kelly, C., Ruff, S. M., Zahedi, K., Shao, M., Bean, J., et al. (2005) · The Lancet · doi:10.1016/s0140-6736(05)74811-x · Cited by 2,394
Self-citationHospital-acquired renal insufficiency
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Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
Flo, T. H., Smith, K. D., Sato, S., Rodriguez, D. J., Holmes, M. A., Strong, R. K., Akira, S., & Aderem, A. (2004) · Nature · doi:10.1038/nature03104 · Cited by 1,877
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Self-citationGoetz, D. H., Holmes, M. A., Borregaard, N., Bluhm, M. E., Raymond, K. N., & Strong, R. K. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00708-6 · Cited by 1,355
Cited by
Reactive astrocytes secrete lcn2 to promote neuron death
Bi, F., Huang, C., Tong, J., Qiu, G., Huang, B., Wu, Q., Li, F., Xu, Z., Bowser, R., Xia, X.-G., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1218497110 · Cited by 371
Metadata
- Authors
- Devarajan, P.
- Venue
- Biomarkers in Medicine
- Publisher
- Informa UK Limited
- Published
- 2010-04
- Volume
- 4
- Issue
- 2
- Pages
- 265-280
- ISSN
- 1752-0363 (ISSN-L)
- 1752-0371
- OpenAlex
- W1968969423
- Cited by
- 332
- References
- 112
- FWCI
- 11.70
- Type
- journal article
- Language
- en
- Open access
- green
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- Devarajan, P. (2010). Neutrophil Gelatinase-Associated Lipocalin: A� Promising Biomarker for Human Acute Kidney Injury. Biomarkers in Medicine. https://doi.org/10.2217/bmm.10.12
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
