Update on afatinib-based combination regimens for the treatment of EGFR mutation-positive non-small-cell lung cancer
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afatinib • combination • EGFR • non-small
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The combination of afatinib with EGFR antibodies or bevacizumab has shown promise but some may be associated with considerable treatment-related toxicities.
“Other approaches include the combination of afatinib with EGFR antibodies or bevacizumab, which have shown promise but some may be associated with considerable treatment-related toxicities.”
From Afatinib for the treatment of <i>EGFR</i> mutation-positive NSCLC: A review of clinical findings (2020) · cites this paper as [105]
Cites
Park, K., Tan, E.-H., O'Byrne, K., Zhang, L., Boyer, M., Mok, T., Hirsh, V., Yang, J. C.-H., Lee, K. H., Lu, S., et al. (2016) · The Lancet Oncology · doi:10.1016/s1470-2045(16)30033-x · Cited by 1,183 · see citing works
Solca, F., Dahl, G., Zoephel, A., Bader, G., Sanderson, M., Klein, C., Kraemer, O., Himmelsbach, F., Haaksma, E., & Adolf, G. R. (2012) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.112.197756 · Cited by 865 · see citing works
Lee, J. Y., Sun, J.-M., Lim, S. H., Kim, H. S., Yoo, K. H., Jung, K. S., Song, H.-N., Ku, B. M., Koh, J., Bae, Y.-H., et al. (2016) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-15-1653 · Cited by 36 · see citing works
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Afatinib for the treatment of <i>EGFR</i> mutation-positive NSCLC: A review of clinical findings
Harvey, R. D., Adams, V. R., Beardslee, T., & Medina, P. (2020) · Journal of Oncology Pharmacy Practice · doi:10.1177/1078155220931926 · Cited by 115 · see citing works
- Authors
- Bennouna, J.
- Affiliations
- Centre Hospitalier Universitaire de Nantes (FR)
- Corresponding author
- Bennouna, Jaafar
- ORCID
- Bennouna, Jaafar
- Venue
- Future Oncology
- Publisher
- Informa UK Limited
- Published
- 2017-06-28
- Volume
- 13
- Issue
- 21
- Pages
- 1829-1833
- ISSN
- 1479-6694 (ISSN-L)
- 1744-8301
- OpenAlex
- W2728181306
- Cited by
- 7
- References
- 3
- Citations by year
- 2023: 1 · 2020: 2 · 2019: 2 · 2018: 1 · 2017: 1
- FWCI
- 1.36
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Future Oncology (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Funders
- Boehringer Ingelheim
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Lung Cancer Treatments and Mutations
- Health Sciences › Medicine › Oncology › HER2/EGFR in Cancer Research
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Lung Cancer Diagnosis and Treatment
- Keywords
- afatinib, EGFR mutation, non-small cell lung cancer, combination therapy, tyrosine kinase inhibitors
- MeSH terms
- Afatinib, Antineoplastic Combined Chemotherapy Protocols, Carcinoma, Non-Small-Cell Lung, Clinical Trials as Topic, Humans, Lung Neoplasms, Mutation, Quinazolines, Signal Transduction, Treatment Outcome, Protein Kinase Inhibitors, Molecular Targeted Therapy, ErbB Receptors
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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